Control of the radicality of brain tumor removal using intraoperative ultrasound imaging

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Abstract

Introduction. Achieving maximal radical resection is a critical factor influencing the prognosis of patients with brain tumors. Intraoperative ultrasound (IOUS) is a promising method for intraoperative control; however, its role in assessing resection radicality and intraoperative decision-making requires further study.

Aim. To evaluate the effectiveness of IOUS for monitoring the radical resection of primary and metastatic brain tumors.

Materials and methods. A prospective study included 58 patients who underwent surgery between January 2023 and September 2024. All patients underwent repeated IOUS in B-mode and with contrast enhancement after the main tumor volume removal to detect residual tumor tissue.

Results. Repeated IOUS identified residual tumor foci (minimum size up to 4 mm) in 17 (29.3 %) patients, leading to continued resection and achieving total or subtotal resection in 100 % of cases. The method provided visualization of tumor boundaries, differentiation from perifocal edema, and monitoring of intraoperative complications.

Conclusion. Intraoperative ultrasound is a highly informative, cost-effective, and safe method that significantly improves the radicality of neurosurgical interventions and can be recommended for widespread integration into clinical practice.

About the authors

Yu. Yu. Dyshchirov

P. A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia

Author for correspondence.
Email: dychshirov03@gmail.com
ORCID iD: 0009-0004-1976-7823
Russian Federation, 3 2nd Botkinsky Proezd, Moscow 125284

L. A. Mitina

P. A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia

Email: dychshirov03@gmail.com
ORCID iD: 0000-0002-3563-7293
Russian Federation, 3 2nd Botkinsky Proezd, Moscow 125284

A. M. Zaitsev

P. A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia

Email: dychshirov03@gmail.com
ORCID iD: 0000-0002-1905-9083
Russian Federation, 3 2nd Botkinsky Proezd, Moscow 125284

S. S. Stepanov

P. A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia

Email: dychshirov03@gmail.com
ORCID iD: 0000-0001-8804-2237
Russian Federation, 3 2nd Botkinsky Proezd, Moscow 125284

O. N. Kirsanova

P. A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia

Email: dychshirov03@gmail.com
ORCID iD: 0000-0003-0924-6245
Russian Federation, 3 2nd Botkinsky Proezd, Moscow 125284

O. V. Guts

P. A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia

Email: dychshirov03@gmail.com
ORCID iD: 0000-0001-5874-2208
Russian Federation, 3 2nd Botkinsky Proezd, Moscow 125284

M. S. Ruban

P. A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia

Email: dychshirov03@gmail.com
ORCID iD: 0000-0002-1016-2009
Russian Federation, 3 2nd Botkinsky Proezd, Moscow 125284

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Copyright (c) 2026 Dyshchirov Y.Y., Mitina L.A., Zaitsev A.M., Stepanov S.S., Kirsanova O.N., Guts O.V., Ruban M.S.

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