Head and Neck TumorsHead and Neck TumorsОпухоли головы и шеи2222-14682411-4634Publishing House ABV Press110.17650/2222-1468-2012-0-1-9-13DIAGNOSIS AND TREATMENT OF HEAD AND NECK TUMORSДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ ГОЛОВЫ И ШЕИIMMEDIATE RESULTS OF CONFORMIC HDR BRACHYTHERAPY USING THE MULTISOURCE APPARATUS FOR ORAL MUCOSAL TUMORSНЕПОСРЕДСТВЕННЫЕ РЕЗУЛЬТАТЫ КОНФОРМНОЙ HDR-БРАХИТЕРАПИИ ОПУХОЛЕЙ СЛИЗИСТОЙ ОБОЛОЧКИ ПОЛОСТИ РТА НА АППАРАТЕ MULTISOURCELozhkovA. A.ЛожковА. А.
Russian Federation
VazheninA. V.ВаженинА. В.
Russian Federation
SharaburaT. M.ШарабураТ. М.
Russian Federation
tatyana1612@yandex.ruAladinA. S.АладинА. С.
Russian Federation
ZhumabayevaA. G.ЖумабаеваА. Г.
Russian Federation
TurbinaA. V.ТурбинаА. В.
Russian Federation
Mozerova,E. Ya.МозероваЕ. Я.
Russian Federation
DavydovaO. N.ДавыдоваО. Н.
Russian Federation
ГБУЗ «Челябинский окружной клинический онкологический диспансер» Минздрава России, ЧелябинскГБУЗ «Челябинский окружной клинический онкологический диспансер» Минздрава России14042012219131404201514042015Copyright ©; 2012, Lozhkov A.A., Vazhenin A.V., Sharabura T.M., Aladin A.S., Zhumabayeva A.G., Turbina A.V., Mozerova, E.Y., Davydova O.N.Copyright ©; 2012, Ложков А.А., Важенин А.В., Шарабура Т.М., Аладин А.С., Жумабаева А.Г., Турбина А.В., Мозерова Е.Я., Давыдова О.Н.2012Lozhkov A.A., Vazhenin A.V., Sharabura T.M., Aladin A.S., Zhumabayeva A.G., Turbina A.V., Mozerova, E.Y., Davydova O.N.Ложков А.А., Важенин А.В., Шарабура Т.М., Аладин А.С., Жумабаева А.Г., Турбина А.В., Мозерова Е.Я., Давыдова О.Н.https://creativecommons.org/licenses/by/4.0https://ogsh.abvpress.ru/jour/article/view/1

In February to August 2011, the Chelyabinsk District Clinical Oncology Dispensary performed combined radiotherapy using conformic HDR brachytherapy (BT) with daily dose fractionaton on a Multisource apparatus in 10 patients with squamous cell carcinoma of the oral mucosa. An algorithm for planning conformic BT was developed, by combining the data of multislice spiral computed tomography and magnetic resonance imaging, by using the inverse procedures for dose calculation, and by choosing the parameters of plan assessment. No complications or severe toxic reactions were noted. The immediate results of the treatment were studied. A complete effect was obtained in 4 patients with Stages I−II. There was process stabilization in 2 patients and continued tumor growth in 1 case. Recurrent tumor was diagnosed in 2 cases following 3 and 9 months. The enhanced efficiency of BT was associated with the increased accuracy of tumor imaging.

В период с февраля по август 2011 г. в ГЛПУ ЧОКОД 10 больным с плоскоклеточным раком слизистой оболочки полости рта проведено сочетанное лучевое лечение с использованием конформной брахитерапии (БТ) в режиме HDR с дневным дроблением дозы на аппарате Multisource. Разработан алгоритм планирования конформной БТ на основании совмещения данных мультиспиральной компьютерной томографии и магнитно-резонансной томографии, применения инверсных методик расчета дозы, выбора параметров оценки плана. Осложнений, тяжелых токсических реакций не отмечено. Изучены непосредственные результаты лечения. Полный эффект получен у 4 больных с I−II стадиями. Стабилизация процесса отмечена у 2 больных, продолженный рост опухоли — в 1 случае. Рецидив диагностирован в 2 случаях, через 3 и 9 мес. Повышение эффективности БТ связано с повышением точности визуализации опухоли.

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