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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1002</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2024-14-3-30-40</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DIAGNOSIS AND TREATMENT OF HEAD AND NECK TUMORS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ ГОЛОВЫ И ШЕИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Medium-term oncological outcome endoscopic surgery malignant tumors of the nasal cavity and paranasal sinuses</article-title><trans-title-group xml:lang="ru"><trans-title>Среднесрочные онкологические результаты эндоскопических вмешательств при злокачественных опухолях полости носа и придаточных пазух</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bolotin</surname><given-names>M. V.</given-names></name><name xml:lang="ru"><surname>Болотин</surname><given-names>М. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow 115522</p></bio><bio xml:lang="ru"><p>115552 Москва, Каширское шоссе, 24</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mudunov</surname><given-names>A. M.</given-names></name><name xml:lang="ru"><surname>Мудунов</surname><given-names>А. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>111 1st Uspenskoe Shosse, Lapino, Moscow Region 143081</p></bio><bio xml:lang="ru"><p>143081 Московская обл., д. Лапино, 1-е Успенское шоссе, 111</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Raportinova</surname><given-names>A. E.</given-names></name><name xml:lang="ru"><surname>Рапортинова</surname><given-names>А. Э.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>28 Orekhovy Boulevard, Moscow 115682</p></bio><bio xml:lang="ru"><p>115682 Москва, Ореховый бульвар, 28</p></bio><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Peshko</surname><given-names>D. A.</given-names></name><name xml:lang="ru"><surname>Пешко</surname><given-names>Д. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow 115522</p></bio><bio xml:lang="ru"><p>115552 Москва, Каширское шоссе, 24</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin National Medical Research Center of Oncology</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Clinical Hospital “Lapino” of the “Mother and Child” Group of companies</institution></aff><aff><institution xml:lang="ru">Клинический госпиталь «Лапино» группы компаний «Мать и дитя»</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Federal Scientific and Clinical Center for Specialized Types of Medical Care and Medical Technologies of the Federal Medical and Biological Agency of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Федеральный научно-клинический центр специализированных видов медицинской помощи и медицинский технологий Федерального медико-биологического агентства России»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-11-12" publication-format="electronic"><day>12</day><month>11</month><year>2024</year></pub-date><volume>14</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>30</fpage><lpage>40</lpage><history><date date-type="received" iso-8601-date="2024-11-12"><day>12</day><month>11</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-11-12"><day>12</day><month>11</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Bolotin M.V., Mudunov A.M., Raportinova A.E., Peshko D.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Болотин М.В., Мудунов А.М., Рапортинова А.Э., Пешко Д.А.</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Bolotin M.V., Mudunov A.M., Raportinova A.E., Peshko D.A.</copyright-holder><copyright-holder xml:lang="ru">Болотин М.В., Мудунов А.М., Рапортинова А.Э., Пешко Д.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/1002">https://ogsh.abvpress.ru/jour/article/view/1002</self-uri><abstract xml:lang="en"><p>Introduction. Transnasal endoscopic resection of sinonasal tumors is currently used in many clinics around the world. Short- and long-term oncological outcomes primarily depend on tumor histology. However, most currently existing studies are based on a small number of observations due to the rarity and heterogeneity of sinonasal malignancy.Aim. To evaluate short- and medium-term oncological outcomes of treatment of malignant sinonasal tumors. Materials and methods. The study is based on retrospective analysis of 95 patients who underwent endoscopic surgery for sinonasal malignancy between 2014 and 2023 at the N.N. Blokhin National medical Research Center of Oncology. Squamous cell carcinoma was diagnosed in 27 (28.4 %) patients, olfactory neuroblastoma in 13 (13.7 %), mucosal melanoma in 30 (31.6 %), adenocarcinoma in (6.3 %), adenoid cystic carcinoma in 7 (7.3 %), sarcomas in 12 (12.7 %). Results. In the study group, 2-years overall survival and recurrence-free survival were 81.3 and 61.4 % respectively, survival without local recurrence was 87.5 %. The outcomes significantly depended on tumor histology.Conclusion. Oncological outcomes of endoscopic resections of sinonasal tumors significantly depend on tumor histology, but in general they allow to achieve good local control. Small number of observations, variety of histological forms, and short follow-up periods do not allow to accurately evaluate the effectiveness of this approach for each tumor type. further research in large populations is needed to establish risk factors.</p></abstract><trans-abstract xml:lang="ru"><p>Введение. Трансназальные эндоскопические вмешательства в настоящее время активно используются в различных клиниках мира для лечения злокачественных опухолей синоназальной локализации. Непосредственные и отдаленные онкологические результаты лечения во многом зависят от гистологического строения опухоли. Однако в связи с редкостью и морфологическим разнообразием данной патологии большинство существующих в настоящее время исследований основаны на небольшом количестве наблюдений, разнородных по гистологическому строению групп новообразований.Цель исследования – оценить непосредственные и среднесрочные онкологические результаты лечения злокачественных опухолей полости носа и придаточных пазух.Материалы и методы. за период с 2014 по 2023 г. в Национальном медицинском исследовательском центре онкологии им. Н.Н. блохина 95 пациентам выполнены эндоскопические резекции. у 27 (28,4 %) больных был плоскоклеточный рак, у 13 (13,7 %) – эстейзионейробластома, у 30 (31,6 %) – меланома, у 6 (6,3 %) – аденокарцинома, у 7 (7,3 %) – аденокистозный рак, у 12 (12,7 %) – саркомы.Результаты. Общая и безрецидивная 2-летняя выживаемость пациентов, включенных в наше исследование, составила 81,3 и 64,1 % соответственно, выживаемость без местного рецидива – 87,5 %. Результаты существенно варьируют в зависимости от гистологического строения опухоли.Заключение. Онкологические результаты трансназальных эндоскопических вмешательств зависят от гистологического строения опухоли, но в целом позволяют получить хороший локальный контроль. Небольшое число наблюдений, разнообразие морфологических форм опухолей и малые сроки наблюдений не позволяют четко определить эффективность данного метода при каждом типе опухоли. Требуются дальнейшие исследования на больших популяциях. </p></trans-abstract><kwd-group xml:lang="en"><kwd>nasal cavity</kwd><kwd>malignant tumor</kwd><kwd>transnasal intervention</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>полость носа</kwd><kwd>злокачественная опухоль</kwd><kwd>трансназальное вмешательство</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Goffart Y., Jorissen M., Daele J. et al. 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