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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1029</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2024-14-4-86-90</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Laryngeal chondrosarcoma (clinical case)</article-title><trans-title-group xml:lang="ru"><trans-title>Хондросаркома гортани (клинический случай)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Trubin</surname><given-names>D. V.</given-names></name><name xml:lang="ru"><surname>Трубин</surname><given-names>Д. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Dmitry Vasilyevich Trubin</p><p>Bld. 5, 6 Zalesskogo St., Novosibirsk 630047</p><p>1 Pirogova St., Novosibirsk 630090</p></bio><bio xml:lang="ru"><p>Дмитрий Васильевич Трубин</p><p>630047 Новосибирск, ул. Залесского, 6, корп. 5</p><p>630090 Новосибирск, ул. Пирогова, 1</p></bio><email>doktortrubin@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kretova</surname><given-names>K. A.</given-names></name><name xml:lang="ru"><surname>Кретова</surname><given-names>К. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>1 Pirogova St., Novosibirsk 630090</p></bio><bio xml:lang="ru"><p>630090 Новосибирск, ул. Пирогова, 1</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Morozov</surname><given-names>D. V.</given-names></name><name xml:lang="ru"><surname>Морозов</surname><given-names>Д. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Bld. 5, 6 Zalesskogo St., Novosibirsk 630047</p></bio><bio xml:lang="ru"><p>630047 Новосибирск, ул. Залесского, 6, корп. 5</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shevchenko</surname><given-names>S. P.</given-names></name><name xml:lang="ru"><surname>Шевченко</surname><given-names>С. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Bld. 5, 6 Zalesskogo St., Novosibirsk 630047</p><p>1 Pirogova St., Novosibirsk 630090</p></bio><bio xml:lang="ru"><p>630047 Новосибирск, ул. Залесского, 6, корп. 5</p><p>630090 Новосибирск, ул. Пирогова, 1</p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">City Clinical Hospital No. 1</institution></aff><aff><institution xml:lang="ru">ГБУЗ НСО «Городская клиническая больница №1»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Novosibirsk National Research State University</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО «Новосибирский национальный исследовательский государственный университет»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2024-12-27" publication-format="electronic"><day>27</day><month>12</month><year>2024</year></pub-date><volume>14</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>86</fpage><lpage>90</lpage><history><date date-type="received" iso-8601-date="2025-01-17"><day>17</day><month>01</month><year>2025</year></date><date date-type="accepted" iso-8601-date="2025-01-17"><day>17</day><month>01</month><year>2025</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Trubin D.V., Kretova K.A., Morozov D.V., Shevchenko S.P.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Трубин Д.В., Кретова К.А., Морозов Д.В., Шевченко С.П.</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Trubin D.V., Kretova K.A., Morozov D.V., Shevchenko S.P.</copyright-holder><copyright-holder xml:lang="ru">Трубин Д.В., Кретова К.А., Морозов Д.В., Шевченко С.П.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/1029">https://ogsh.abvpress.ru/jour/article/view/1029</self-uri><abstract xml:lang="en"><p>Laryngeal chondrosarcoma is a rare malignant tumor that originates from cartilage tissue. The incidence of this pathology varies from 1 to 12 %. Only isolated clinical cases of laryngeal chondrosarcoma and observations of small groups of patients with this disease are described  since statistical data on such rare types of tumors are often unavailable. Survival in this pathology may vary depending on various factors  such as the stage of the disease  the size of the tumor  the presence of metastases  the general condition of the patient and the effectiveness of treatment. Since laryngeal chondrosarcoma is a rare disease  there is relatively little scientific data on prognosis and survival. The article presents a clinical case of diagnosis of treatment and primary chondrosarcoma of the larynx.</p></abstract><trans-abstract xml:lang="ru"><p>Хондросаркома гортани – редкая злокачественный опухоль, которая происходит из хрящевой ткани. Частота встречаемости этой патологии варьирует от 1 до 12 %. Описаны лишь отдельные клинические случаи хондросаркомы гортани и наблюдения за малыми группами пациентов с этими новообразованиями, поскольку статистические данные по таким редким типам опухолей зачастую недоступны. Выживаемость при этой патологии может варьировать в зависимости от различных факторов, таких как стадия заболевания, размер опухоли, наличие метастазов, общее состояние больного и эффективность лечения. Поскольку хондросаркома гортани является редким заболеванием, научных данных о прогнозе и выживаемости относительно мало.</p><p>В статье представлен клинический случай диагностики и лечения первичной хондросаркомы гортани.</p></trans-abstract><kwd-group xml:lang="en"><kwd>chondrosarcoma</kwd><kwd>larynx</kwd><kwd>rare malignant tumor</kwd><kwd>laryngectomy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>хондросаркома</kwd><kwd>гортань</kwd><kwd>редкая злокачественная опухоль</kwd><kwd>ларингэктомия</kwd></kwd-group><funding-group><funding-statement xml:lang="en">The authors express their gratitude for scientific advice to MD, Professor S.V. Sidorov and MD, Professor I.G. Sergeeva.</funding-statement><funding-statement xml:lang="ru">Авторы выражают благодарность за научное консультирование д.м.н., проф. С.В. Сидорову и д.м.н., проф. И.Г. Сергеевой.</funding-statement></funding-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Nizhelskoy D.A., Moshurov I.P., Antonenkov Yu.E. Modern epidemiological aspects and medical and social factors of malignant neoplasms of the larynx (review article). Sovremennye problemy zdravoohraneniya i medicinskoj statistiki = Current Problems of Health Care and Medical statistics2023;1:622–42. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Нижельской Д.А., Мошуров И.П., Антоненков Ю.Е. Современные эпидемиологические аспекты и медико-социальные факторы злокачественных новообразований гортани (обзорная статья). Современные проблемы здравоохранения и медицинской статистики 2023;1:622–42. DOI: 10.24412/2312-2935-2023-1-622-642</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Makhonin A.A., Vladimirova T.Yu., Gabrielyan A.G. et al. Case report of chondrosarcoma of the larynx. Rossiiskaya otorinolaringologiya 2020;19(6):87–93. (In Russ.). DOI: 10.18692/1810-4800-2020-6-87-93</mixed-citation><mixed-citation xml:lang="ru">Махонин А.А., Владимирова Т.Ю., Габриелян А.Г и др. Хондросаркома гортани. Российская оториноларингология 2020;19(6):87–93.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><mixed-citation>Thompson L.D.R., Gannon F.H. Chondrosarcoma of the larynx: a clinicopathologic study of 111 cases with a review of the literature. Am J Surg Pathol 2002;26(7):836–51. DOI: 10.1097/00000478-200207000-00002</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Coca-Pelaz A., Rodrigo J.P., Triantafyllou A. et al. Chondrosarcomas of the head and neck. Eur Arch Otorhinolaryngol 2014;271(10):2601–9. DOI: 10.1007/s00405-013-2807-3</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>De Jong R.J.B., van Lent S., Hogendoorn P.C.W. Chondroma and chondrosarcoma of the larynx Curr Opin Otolaryngol Head Neck Surg 2004;12(2):98–105.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Adeola J.O., Patel J.S., Povolotskiy R. et al. Clinicopathologic characteristics of laryngeal chondrosarcoma: an analysis of the National Cancer Database. Auris Nasus Larynx 2021;48(5):956–62. DOI: 10.1016/j.anl.2021.02.014</mixed-citation></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">Abdurakhmоnov O.B., Khudаerov M.S., Khatamov Sh.N. Chondrosarcoma of larynx (case report). Uzbek Journal of Case Reports 2023;3(1):12–6. (In Russ.). DOI: 10.55620/ujcr.3.1.2023.2</mixed-citation><mixed-citation xml:lang="ru">Абдурахмонов О.Б., Худаёров М.С., Хатамов Ш.Н. Хондрасаркома гортани (случай из практики). Uzbek Journal of Case Reports 2023;3(1):12–6. DOI: 10.55620/ujcr.3.1.2023.2</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><mixed-citation>Chin O.Y., Dubal P.M., Sheikh A.B. et al. Laryngeal chondrosarcoma: a systematic review of 592 cases. Laryngoscope 2017;127(2):430–9. DOI: 10.1002/lary.26068</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Dailiana T., Nomikos P., Kapranos N. et al. Chondrosarcoma of the larynx: treatment with radiotherapy. Skeletal Radiol 2002;31:547–9. DOI: 10.1007/s00256-002-0527-7</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Galletti B., Costanzo D., Gazia F., Galletti F. et al. High-grade chondrosarcoma of the larynx: treatment and management. BMJ Case Rep 2019;12(9):e230918. DOI: 10.1136/bcr-2019-230918</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Schleich M., Laccourreye L., Marianowski R. et al. Treatment strategy in laryngeal chondrosarcoma: a multicenter study of 43 cases. Eur Arch Otorhinolaryngol 2024;281:883–90. DOI: 10.1007/s00405-023-08248-7</mixed-citation></ref></ref-list></back></article>
