Head and Neck TumorsHead and Neck TumorsОпухоли головы и шеи2222-14682411-4634Publishing House ABV Press12010.17650/2222-1468-2015-1-27-35LITERATURE REVIEWОБЗОР ЛИТЕРАТУРЫTHE HISTORY OF STEREOTACTIC RADIOSURGERY DEVELOPMENT AND ITS ROLE IN THE TREATMENT OF BRAIN METASTASESИСТОРИЯ РАЗВИТИЯ СТЕРЕОТАКСИЧЕСКОЙ РАДИОХИРУРГИИ И ЕЕ РОЛЬ В ЛЕЧЕНИИ МЕТАСТАЗОВ В ГОЛОВНОЙ МОЗГEngelO. T.ЭнгелО. Т.
Russian Federation

Radiosurgery Clinic «Onkostop»; Bldg. 4, 23 Kashirskoye Shosse,Moscow, 115478,Russia

Контакты: Ольга Тиборовна Энгел oe@oncostop.me

Клиника лучевой хирургии «Онкостоп»; Россия, 115478, Москва, Каширское шоссе, 23, стр. 4

oe@oncostop.meNazarenkoA. V.НазаренкоА. В.
Russian Federation
oe@oncostop.meRadiosurgery Clinic «Onkostop», MoscowКлиника лучевой хирургии «Онкостоп», Москва150420155127351904201519042015Copyright ©; 2015, Engel O.T., Nazarenko A.V.Copyright ©; 2015, Энгел О.Т., Назаренко А.В.2015Engel O.T., Nazarenko A.V.Энгел О.Т., Назаренко А.В.https://creativecommons.org/licenses/by/4.0https://ogsh.abvpress.ru/jour/article/view/120

 

Metastases of primary tumors to the brain develop in 20–40 % of cancer patients. Historical information about the origin and development of the stereotactic radiosurgery method are shown, including GammaKnife and CyberKnife. The development of new centers of radiosurgery in the world makes the method more accessible for patients. The article examines the modern treatment algorithm for cerebral metastases and the place of stereotactic radiosurgery as a high-dose conformal ablative treatment of selected metastatic lesions in the management of these patients. It is shown that radiosurgery provides a high level of local control and survival, similar to surgical resection.

The results of trails with combination of the stereotactic radiosurgery and total brain radiation therapy in patients with solitary and multiple lesions are reported. It is shown that the radiosurgery allows to avoid total irradiation in case of solitary metastasis, and also in case of multiple lesions, without affecting the survival. That, probably, helps to preserve neurocognitive function and quality of life for patients with good performance status according to Karnofsky scale (index ³ 70). We also discuss the possibility of stereotactic irradiation of postoperative cavity. The concept of radiosurgery is not divided upon the treatment platform.

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