Head and Neck TumorsHead and Neck TumorsОпухоли головы и шеи2222-14682411-4634Publishing House ABV Press17010.17650/2222-1468-2015-5-3-39-44ORIGINAL REPORTSОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯThe role of endocrine factors in diagnostics of thyroid cancer by sonoelastographyРоль эндокринных показателей при диагностике рака щитовидной железы путем ультразвуковой компрессионной эластографииVasilyevD. A.ВасильевД. А.
Russian Federation
dvasilyev@hotmail.comKostrominaE. V.КостроминаЕ. В.
Russian Federation
RadzhabovaZ. A.РаджабоваЗ. А.
Russian Federation
KrasilnikovaL. A.КрасильниковаЛ. А.
Russian Federation
RakitinaD. A.РакитинаД. А.
Russian Federation
GurinA. V.ГуринА. В.
Russian Federation
NazhmudinovR. A.НажмудиновР. А.
Russian Federation
DunaevskiyI. V.ДунаевскийИ. В.
Russian Federation
BersteinL. M.БерштейнЛ. М.
Russian Federation
Department of Urologic Oncology, N. N. Petrov Research Institute of Oncology, Ministry of Health of RussiaФГБУ «Научно-исследовательский институт онкологии им. Н. Н. Петрова» Минздрава России68 Leningradskaya St., Pesochnyi Settlement, Saint Petersburg, 197758, RussiaРоссия, 197758, Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68241120155339442411201524112015Copyright ©; 2015, Vasilyev D.A., Kostromina E.V., Radzhabova Z.A., Krasilnikova L.A., Rakitina D.A., Gurin A.V., Nazhmudinov R.A., Dunaevskiy I.V., Berstein L.M.Copyright ©; 2015, Васильев Д.А., Костромина Е.В., Раджабова З.А., Красильникова Л.А., Ракитина Д.А., Гурин А.В., Нажмудинов Р.А., Дунаевский И.В., Берштейн Л.М.2015Vasilyev D.A., Kostromina E.V., Radzhabova Z.A., Krasilnikova L.A., Rakitina D.A., Gurin A.V., Nazhmudinov R.A., Dunaevskiy I.V., Berstein L.M.Васильев Д.А., Костромина Е.В., Раджабова З.А., Красильникова Л.А., Ракитина Д.А., Гурин А.В., Нажмудинов Р.А., Дунаевский И.В., Берштейн Л.М.https://creativecommons.org/licenses/by/4.0https://ogsh.abvpress.ru/jour/article/view/170

The role of real-time elastography or sonoelastography has been widely discussed recently. However, there are practically no publications which showed the influence of endocrine status in the process for improving of diagnostic value of this method; this issue was the aim of our study. 128 patients (31 – benign adenomas and 97 – thyroid cancer: 13 – follicular and 84 – papillary) were evaluated prospectively. Mean age was 48.3 ± 15.9 years. It was confirmed that the blue colour or 4–5 elastotype of sonoelastography was mainly discovered in thyroid cancer vs adenoma (73.2 % vs 25.8 %, χ2 = 18.96, р = 0.0001). Parameters of the sensitivity, specificity and accuracy were equal 90.7 %, 54.8 % and 82.0 % for sonoelastography, and 95.9 %, 45.2 % and 83.6 % for fine-needle aspiration biopsy, respectively. The combination of sonoelastography with fine-needle aspiration biopsy or with body mass index, presurgical glucose or thyroid-stimulating hormone level increased specificity of sonoelastography by 65.0 %, 70.0 %, 64.7 % and 63.2 %, respectively. Thus, sonoelastography had the same diagnostic accuracy as fine-needle aspiration biopsy in predicting of thyroid cancer. The specificity of sonoelastography could be increased by combination with fine-needle aspiration biopsy as well as thyroid-stimulating hormone or glucose level and body mass index value.

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