Head and Neck TumorsHead and Neck TumorsОпухоли головы и шеи2222-14682411-4634Publishing House ABV Press18410.17650/2222-1468-2015-5-4-48-52LITERATURE REVIEWОБЗОР ЛИТЕРАТУРЫClinical features of the head and neck mucosal melanoma. А reviewОсобенности клинического течения меланомы слизистых оболочек головы и шеи. Обзор литературыIgnatovaA. V.ИгнатоваА. В.
Russian Federation

2 / 1 Barrikadnaya St., Moscow, 125993

125993, Москва, ул. Баррикадная, 2 / 1

annasurge@gmail.comMudunovA. M.МудуновА. М.
Russian Federation

23 Kashirskoe Shosse, Moscow, 115478

115478, Москва, Каширское шоссе, 23

PodvyaznikovS. O.ПодвязниковС. О.
Russian Federation

2 / 1 Barrikadnaya St., Moscow, 125993

125993, Москва, ул. Баррикадная, 2 / 1

Department of Oncology, Russian Medical Academy of Post-Graduate Education at the Ministry of Health of RussiaКафедра онкологии ГБОУ ДПО «Российская медицинская академия последипломного образования» Минздрава РоссииN.N. Blokhin Russian Cancer Research Center, Ministry of Health of RussiaФГБУ «РОНЦ им. Н.Н. Блохина» Минздрава России301220155448521601201616012016Copyright ©; 2015, Ignatova A.V., Mudunov A.M., Podvyaznikov S.O.Copyright ©; 2015, Игнатова А.В., Мудунов А.М., Подвязников С.О.2015Ignatova A.V., Mudunov A.M., Podvyaznikov S.O.Игнатова А.В., Мудунов А.М., Подвязников С.О.https://creativecommons.org/licenses/by/4.0https://ogsh.abvpress.ru/jour/article/view/184

Melanoma is an aggressive and rare neoplasm of melanocytic origin. Mucosal melanomas of the head and neck account for 1 % of neoplasms, 0,2–8,0 4 % of all melanomas and over 50 % of all mucosal melanomas. To date, in Russian and foreign literature only few retrospective series and case reports have been reported on mucosal melanoma. Despite melanoma’s common histological origin, head and neck mucosal melanoma presentation has some specific features due to its anatomical localization and poor clinical outcomes compared with those of cutaneous melanomas. Mucosal melanoma has a high metastatic potential. Five-year overall survival does not exceed 30 %. Advances in understanding of the clinical presentation can be used for prediction of behaviour and prognosis of this disease. We considered and analised articles devoted to clinical features of head and neck mucosal melanoma according to its localization.

Меланома – злокачественная опухоль, развивающаяся из меланоцитов. Меланомы слизистых оболочек головы и шеи составляют 0,2–8,0 % всех меланом, 1 % всех новообразований головы и шеи, и более 50 % всех меланом слизистых оболочек. В отечественной и зарубежной литературе в основном встречаются описания лишь отдельных клинических случаев заболевания. Несмотря на единый гистогенез, меланомы слизистых оболочек головы и шеи имеют ряд особенностей в силу специфического анатомо-топографического расположения очага и характеризуются более неблагоприятным клиническим прогнозом по сравнению с кожными формами. При этом меланомы слизистых оболочек обладают высоким метастатическим потенциалом. Пятилетняя общая вы- живаемость не превышает 30 %. Понимание особенностей клинического течения меланомы слизистых оболочек головы и шеи необходимо для определения прогноза заболевания.

В данной статье выполнен анализ публикаций, посвященных описанию клинических проявлений заболевания и характерным особенностям клинического течения в зависимости от локализации опухоли.

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