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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">185</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2015-5-4-53-57</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Locally advanced thyroid cancer: case report</article-title><trans-title-group xml:lang="ru"><trans-title>Местно-распространенный рак щитовидной железы. Случай из практики</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Azizyan</surname><given-names>R. I.</given-names></name><name xml:lang="ru"><surname>Азизян</surname><given-names>Р. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>23 Kashirskoe Shosse, Moscow, 115478</p></bio><bio xml:lang="ru"><p>115478, Москва, Каширское шоссе, 23</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Saprina</surname><given-names>O. A.</given-names></name><name xml:lang="ru"><surname>Саприна</surname><given-names>О. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>23 Kashirskoe Shosse, Moscow, 115478</p></bio><bio xml:lang="ru"><p>115478, Москва, Каширское шоссе, 23</p></bio><email>isabekian@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bekyashev</surname><given-names>A. Kh.</given-names></name><name xml:lang="ru"><surname>Бекяшев</surname><given-names>А. Х.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>23 Kashirskoe Shosse, Moscow, 115478</p></bio><bio xml:lang="ru"><p>115478, Москва, Каширское шоссе, 23</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Belov</surname><given-names>D. S.</given-names></name><name xml:lang="ru"><surname>Белов</surname><given-names>Д. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>23 Kashirskoe Shosse, Moscow, 115478</p></bio><bio xml:lang="ru"><p>115478, Москва, Каширское шоссе, 23</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gasparyan</surname><given-names>T. G.</given-names></name><name xml:lang="ru"><surname>Гаспарян</surname><given-names>Т. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>23 Kashirskoe Shosse, Moscow, 115478</p></bio><bio xml:lang="ru"><p>115478, Москва, Каширское шоссе, 23</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gorobets</surname><given-names>E. S.</given-names></name><name xml:lang="ru"><surname>Горобец</surname><given-names>Е. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>23 Kashirskoe Shosse, Moscow, 115478</p></bio><bio xml:lang="ru"><p>115478, Москва, Каширское шоссе, 23</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Balandin</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Баландин</surname><given-names>В. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>23 Kashirskoe Shosse, Moscow, 115478</p></bio><bio xml:lang="ru"><p>115478, Москва, Каширское шоссе, 23</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ungiadze</surname><given-names>G. V.</given-names></name><name xml:lang="ru"><surname>Унгиадзе</surname><given-names>Г. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>23 Kashirskoe Shosse, Moscow, 115478</p></bio><bio xml:lang="ru"><p>115478, Москва, Каширское шоссе, 23</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Dronova</surname><given-names>E. L.</given-names></name><name xml:lang="ru"><surname>Дронова</surname><given-names>Е. Л.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>23 Kashirskoe Shosse, Moscow, 115478</p></bio><bio xml:lang="ru"><p>115478, Москва, Каширское шоссе, 23</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Vasil’ev</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Васильев</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>23 Kashirskoe Shosse, Moscow, 115478</p></bio><bio xml:lang="ru"><p>115478, Москва, Каширское шоссе, 23</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Lomaya</surname><given-names>M. V.</given-names></name><name xml:lang="ru"><surname>Ломая</surname><given-names>М. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Build. 2, 8 Trubetskaya St., Moscow, 119991</p></bio><bio xml:lang="ru"><p>119991, Москва, ул. Трубецкая, 8, стр. 2</p></bio><xref ref-type="aff" rid="aff3"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin Russian Cancer Research Center at the Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «РОНЦ им. Н.Н. Блохина» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">N.N. Blokhin Russian Cancer Research Center at the Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru"></institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">I.M. Sechenov First Moscow State Medical University at the Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО «Первый МГМУ им. И.М. Сеченова» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2015-12-30" publication-format="electronic"><day>30</day><month>12</month><year>2015</year></pub-date><volume>5</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>53</fpage><lpage>57</lpage><history><date date-type="received" iso-8601-date="2016-01-16"><day>16</day><month>01</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-01-16"><day>16</day><month>01</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2015, Azizyan R.I., Saprina O.A., Bekyashev A.K., Belov D.S., Gasparyan T.G., Gorobets E.S., Balandin V.V., Ungiadze G.V., Dronova E.L., Vasil’ev A.V., Lomaya M.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2015, Азизян Р.И., Саприна О.А., Бекяшев А.Х., Белов Д.С., Гаспарян Т.Г., Горобец Е.С., Баландин В.В., Унгиадзе Г.В., Дронова Е.Л., Васильев А.В., Ломая М.В.</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="en">Azizyan R.I., Saprina O.A., Bekyashev A.K., Belov D.S., Gasparyan T.G., Gorobets E.S., Balandin V.V., Ungiadze G.V., Dronova E.L., Vasil’ev A.V., Lomaya M.V.</copyright-holder><copyright-holder xml:lang="ru">Азизян Р.И., Саприна О.А., Бекяшев А.Х., Белов Д.С., Гаспарян Т.Г., Горобец Е.С., Баландин В.В., Унгиадзе Г.В., Дронова Е.Л., Васильев А.В., Ломая М.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/185">https://ogsh.abvpress.ru/jour/article/view/185</self-uri><abstract xml:lang="en"><p>The paper gives the results of treatment in a female patient with locally advanced thyroid cancer with a tumor thrombus in the internal jugular vein with laryngeal or tracheal involvement, and a giant metastasis into the bone of the vault of the skull.</p></abstract><trans-abstract xml:lang="ru"><p>В статье представлены результаты лечения пациентки с местно-распространенным раком щитовидной железы с опухолевым тромбом внутренней яремной вены с поражением гортани, трахеи и с «гигантским» метастазом в кости свода черепа.</p></trans-abstract><kwd-group xml:lang="en"><kwd>locally advanced cancer</kwd><kwd>follicular cancer</kwd><kwd>laryngeal or tracheal involvement</kwd><kwd>tumor thrombus</kwd><kwd>distant metastases</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>местно-распространенный рак</kwd><kwd>фолликулярный рак</kwd><kwd>поражение гортани</kwd><kwd>поражение трахеи</kwd><kwd>опухолевый тромб</kwd><kwd>отдаленные метастазы</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. 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