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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">194</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2016-6-1-13-27</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DIAGNOSIS AND TREATMENT OF HEAD AND NECK TUMORS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ ГОЛОВЫ И ШЕИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Esthesioneuroblastoma: clinical course, long-term results of treatment</article-title><trans-title-group xml:lang="ru"><trans-title>Эстезионейробластома (клиническое течение, отдаленные результаты лечения)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tabolinovskaya</surname><given-names>T. D.</given-names></name><name xml:lang="ru"><surname>Таболиновская</surname><given-names>Т. Д.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>9163847739@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Mudunov</surname><given-names>A. M.</given-names></name><name xml:lang="ru"><surname>Мудунов</surname><given-names>А. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Alieva</surname><given-names>S. B.</given-names></name><name xml:lang="ru"><surname>Алиева</surname><given-names>С. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Orel</surname><given-names>N. F.</given-names></name><name xml:lang="ru"><surname>Орел</surname><given-names>Н. Ф.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Komarova</surname><given-names>L. E.</given-names></name><name xml:lang="ru"><surname>Комарова</surname><given-names>Л. Е.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Oganyan</surname><given-names>E. R.</given-names></name><name xml:lang="ru"><surname>Оганян</surname><given-names>Е. Р.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pustynskiy</surname><given-names>I. N.</given-names></name><name xml:lang="ru"><surname>Пустынский</surname><given-names>И. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Khasanov</surname><given-names>R. A.</given-names></name><name xml:lang="ru"><surname>Хасанов</surname><given-names>Р. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Aketova</surname><given-names>T. A.</given-names></name><name xml:lang="ru"><surname>Акетова</surname><given-names>Т. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Pirogova</surname><given-names>N. A.</given-names></name><name xml:lang="ru"><surname>Пирогова</surname><given-names>Н. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Department for Coordination and Introduction of Experience in Diagnosing and Treating Malignancies, Section for Surgery of Head and Neck Tumors, Section of Radiology, Department for Chemotherapy of Malignancies, N.N. Blokhin Russian Cancer Research Center at the Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">Отделение координации и внедрения опыта по диагностике и лечению злокачественных новообразований, отдел хирургии опухолей головы и шеи, отдел радиологии, отделение химиотерапии злокачественных опухолей ФГБУ «Российский онкологический научный центр им. Н.Н. Блохина» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">24 Kashirskoe Shosse, Moscow, 115478, Russia</institution></aff><aff><institution xml:lang="ru">Россия, 115478, Москва, Каширское шоссе, 24</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2016-03-30" publication-format="electronic"><day>30</day><month>03</month><year>2016</year></pub-date><volume>6</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>13</fpage><lpage>27</lpage><history><date date-type="received" iso-8601-date="2016-03-30"><day>30</day><month>03</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-03-30"><day>30</day><month>03</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2016, Tabolinovskaya T.D., Mudunov A.M., Alieva S.B., Orel N.F., Komarova L.E., Oganyan E.R., Pustynskiy I.N., Khasanov R.A., Aketova T.A., Pirogova N.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2016, Таболиновская Т.Д., Мудунов А.М., Алиева С.Б., Орел Н.Ф., Комарова Л.Е., Оганян Е.Р., Пустынский И.Н., Хасанов Р.А., Акетова Т.А., Пирогова Н.А.</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="en">Tabolinovskaya T.D., Mudunov A.M., Alieva S.B., Orel N.F., Komarova L.E., Oganyan E.R., Pustynskiy I.N., Khasanov R.A., Aketova T.A., Pirogova N.A.</copyright-holder><copyright-holder xml:lang="ru">Таболиновская Т.Д., Мудунов А.М., Алиева С.Б., Орел Н.Ф., Комарова Л.Е., Оганян Е.Р., Пустынский И.Н., Хасанов Р.А., Акетова Т.А., Пирогова Н.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/194">https://ogsh.abvpress.ru/jour/article/view/194</self-uri><abstract xml:lang="en"><p><italic>This rare tumor from a group of neuroendocrine neoplasms was studied. The material for the study was the data of 78 patients with esthesioneuroblastoma who had been treated and followed up at the N.N. Blokhin Russian Cancer Research Center in the period 1965 to 2014. Information on hospital statistics, clinical features, methods, and treatment results were presented. The possibilities of using the TNM classification for the nasal cavity, ethmoidal sinuses, and nasopharynx were assessed to determine the anatomic extent of primary tumor. The findings contribute to the solution of problems in the diagnosis and treatment of esthesioneuroblastoma at the present stage. </italic></p></abstract><trans-abstract xml:lang="ru"><p><italic>Проведено изучение редкой опухоли из группы новообразований нейроэндокринной природы. Материалом для исследования послужили данные о 78 больных эстезионейробластомой, которые лечились и наблюдались в РОНЦ им. Н.Н. Блохина в период с 1965 по 2014 г. Представлены сведения госпитальной статистики, особенности клинического течения, методы и результаты лечения. Дана оценка возможности применения TNM-классификации для полости носа, решетчатой пазухи и носоглотки при определении анатомической распространенности первичной опухоли. Полученные данные способствуют решению проблем диагностики и лечения эстезионейробластомы на современном уровне. </italic></p></trans-abstract><kwd-group xml:lang="en"><kwd>esthesioneuroblastoma</kwd><kwd>nasal cavity</kwd><kwd>ethmoidal labyrinth</kwd><kwd>nasopharynx</kwd><kwd>clinical presentation</kwd><kwd>treatment</kwd><kwd>efficiency</kwd><kwd>life expectancy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>эстезионейробластома</kwd><kwd>полость носа</kwd><kwd>решетчатый лабиринт</kwd><kwd>носоглотка</kwd><kwd>клиника</kwd><kwd>лечение</kwd><kwd>эффективность</kwd><kwd>продолжительность жизни</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Гарюк Г.И., Загоруева Л.Л., Шевченко А.М., Почуева Т.В. Эстезионейробластома полости носа и околоносовых пазух. Вестник оториноларингологии 1992;(4):26–7. [Garyuk G.I., Zagorueva L.L., Shevchenko А.М., Pochuevа Т.V. 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