Head and Neck TumorsHead and Neck TumorsОпухоли головы и шеи2222-14682411-4634Publishing House ABV Press19510.17650/2222-1468-2016-6-1-28-32DIAGNOSIS AND TREATMENT OF HEAD AND NECK TUMORSДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ ГОЛОВЫ И ШЕИTransoral laser resections of oral cavity and oropharyngeal tumorsТрансоральные лазерные резекции опухолей полости рта и ротоглоткиBolotinM. V.БолотинМ. В.
Russian Federation
bolotin1980@mail.ruMudunovA. M.МудуновА. М.
Russian Federation
AzizyanR. I.АзизянР. И.
Russian Federation
SaprinaO. A.СапринаО. А.
Russian Federation
N.N. Blokhin Russian Cancer Research Center at the Ministry of Health of RussiaФГБУ «РОНЦ им. Н.Н. Блохина» Минздрава России23 Kashirskoe Shosse, Moscow, 115478, RussiaРоссия, 115478, Москва, Каширское шоссе, 23300320166128323003201630032016Copyright ©; 2016, Bolotin M.V., Mudunov A.M., Azizyan R.I., Saprina O.A.Copyright ©; 2016, Болотин М.В., Мудунов А.М., Азизян Р.И., Саприна О.А.2016Bolotin M.V., Mudunov A.M., Azizyan R.I., Saprina O.A.Болотин М.В., Мудунов А.М., Азизян Р.И., Саприна О.А.https://creativecommons.org/licenses/by/4.0https://ogsh.abvpress.ru/jour/article/view/195

The incidence of squamous cell carcinoma of the head and neck remains high and ranks tenth in the structure of overall cancer morbidity. Surgical radicality has remained one of the major determinants of the long-term results of treatment so far. In the period December 2014 to January 2016, our clinic performed surgical interventions as transoral laser oral cavity and oropharyngeal resections using carbon dioxide (CO2) laser in 34 patients. Tumors are most commonly located in the area of the tongue root and oropharynx in 16 (47.1 %) patients, tongue (its anterior two thirds) in 14 (41.2 %), and mouth floor in 4 (11.7 %). The average length of hospital stay after transoral laser resections was 10.14 days. A nasogastric tube was postoperatively placed in 6 (17.6 %) patients for 8 to 17 days. According to the results of planned histological examination, surgical interventions were microscopically radical in all cases. Transoral CO2 laser resections make possible to perform rather large radical surgical interventions with a satisfactory functional and cosmetic results, without deteriorating the long-term results of treatment. 

squamous cell carcinomaoral cavityoropharynxcarbon dioxide laserплоскоклеточный ракполость ртаротоглоткакарбондиоксидный лазер1. Bagan J.V., Scully C. Recent advances in Oral Oncology 2007: epidemiology, aetiopathogenesis, diagnosis and prognostication. Oral Oncol 2008;44(2):103–8.Bagan J.V., Scully C. Recent advances in Oral Oncology 2007: epidemiology, aetiopathogenesis, diagnosis and prognostication. Oral Oncol 2008;44(2):103–8.2. Warnakulasuriya S. Global epidemiology of oral and oropharyngeal cancer. Oral Oncol 2009;45(4–5): 309–16.Warnakulasuriya S. Global epidemiology of oral and oropharyngeal cancer. Oral Oncol 2009;45(4–5): 309–16.3. Werner J.A., Dunne A.A., Folz B.J., Lippert B.M. Transoral laser microsurgery in carcinomas of the oral cavity, pharynx, and larynx. Cancer Control 2002;9(5):379–86.Werner J.A., Dunne A.A., Folz B.J., Lippert B.M. Transoral laser microsurgery in carcinomas of the oral cavity, pharynx, and larynx. Cancer Control 2002;9(5):379–86.4. Strong M.S., Vaughan C.W., Healy G.B. et al. Transoral management of localized carcinoma of the oral cavity using the CO2 laser. Laryngoscope 1979;89(6 Pt 1):897–905.Strong M.S., Vaughan C.W., Healy G.B. et al. Transoral management of localized carcinoma of the oral cavity using the CO2 laser. Laryngoscope 1979;89(6 Pt 1):897–905.5. Steiner W., Ambrosch P. Endoscopic Laser Surgery of the Upper Aerodigestive Tract. Stuttgart: Thieme, 2000.Steiner W., Ambrosch P. Endoscopic Laser Surgery of the Upper Aerodigestive Tract. Stuttgart: Thieme, 2000.6. Steiner W. Therapy of hypopharyngeal carcinoma. Part V: Discussion of long-term results of transoral laser microsurgery of hypopharyngeal carcinoma. HNO 1994;42(3):157–65.Steiner W. Therapy of hypopharyngeal carcinoma. Part V: Discussion of long-term results of transoral laser microsurgery of hypopharyngeal carcinoma. HNO 1994;42(3):157–65.7. Wang C.P., Chang S.Y., Wu J.D., Tai S.K. Carbon dioxide laser microsurgery for tongue cancer: surgical techniques and longterm results. J Otolaryngol 2001;30(1):19–23.Wang C.P., Chang S.Y., Wu J.D., Tai S.K. Carbon dioxide laser microsurgery for tongue cancer: surgical techniques and longterm results. J Otolaryngol 2001;30(1):19–23.8. Jerjes W., Upile T., Hamdoon Z. et al. Prospective evaluation of outcome after transoral CO(2) laser resection of T1/T2 oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011;112(2):180–7.Jerjes W., Upile T., Hamdoon Z. et al. Prospective evaluation of outcome after transoral CO(2) laser resection of T1/T2 oral squamous cell carcinoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2011;112(2):180–7.9. Rossmann J.A., Brown R.S., Hays G.L., Lusk S.S. Carbon dioxide laser surgical therapy for the management of oral leukoplakia: a case report. Tex Dent J 1994;111(12): 17–9, 21.Rossmann J.A., Brown R.S., Hays G.L., Lusk S.S. Carbon dioxide laser surgical therapy for the management of oral leukoplakia: a case report. Tex Dent J 1994;111(12): 17–9, 21.10. Luomanen M. A comparative study of healing of laser and scalpel incision wounds in rat oral mucosa. Scand J Dent Res 1987;95(1):65–73.Luomanen M. A comparative study of healing of laser and scalpel incision wounds in rat oral mucosa. Scand J Dent Res 1987;95(1):65–73.11. D’Arcangelo C., Di Nardo Di Maio F., Prosperi G.D. et al. A preliminary study of healing of diode laser versus scalpel incisions in rat oral tissue: a comparison of clinical, histological, and immunohistochemical results. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103(6):764–73.D’Arcangelo C., Di Nardo Di Maio F., Prosperi G.D. et al. A preliminary study of healing of diode laser versus scalpel incisions in rat oral tissue: a comparison of clinical, histological, and immunohistochemical results. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2007;103(6):764–73.12. Camp A.A., Fundakowski C., Petruzzelli G.J., Emami B. Functional and oncologic results following transoral laser microsurgical excision of base of tongue carcinoma. Otolaryngol Head Neck Surg 2009;141(1):66–9.Camp A.A., Fundakowski C., Petruzzelli G.J., Emami B. Functional and oncologic results following transoral laser microsurgical excision of base of tongue carcinoma. Otolaryngol Head Neck Surg 2009;141(1):66–9.13. Rich J.T., Milov S., Lewis J.S. Jr et al. Transoral laser microsurgery (TLM) +/adjuvant therapy for advanced stage oropharyngeal cancer: outcomes and prognostic factors. Laryngoscope 2009;119(9):1709–19.Rich J.T., Milov S., Lewis J.S. Jr et al. Transoral laser microsurgery (TLM) +/adjuvant therapy for advanced stage oropharyngeal cancer: outcomes and prognostic factors. Laryngoscope 2009;119(9):1709–19.