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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">206</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2016-6-2-35-41</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DIAGNOSIS AND TREATMENT OF HEAD AND NECK TUMORS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ ГОЛОВЫ И ШЕИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Comprehensive approach in treatment of locally disseminated oropharyngeal cancer</article-title><trans-title-group xml:lang="ru"><trans-title>Комплексный подход в лечении местно-распространенного рака ротоглотки</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kropotov</surname><given-names>M. A.</given-names></name><name xml:lang="ru"><surname>Кропотов</surname><given-names>М. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow, 115478</p></bio><bio xml:lang="ru"><p>115478, Москва, Каширское шоссе, 24</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Yakovleva</surname><given-names>L. P.</given-names></name><name xml:lang="ru"><surname>Яковлева</surname><given-names>Л. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow, 115478</p></bio><bio xml:lang="ru"><p>115478, Москва, Каширское шоссе, 24</p></bio><email>lpopkova@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Dronova</surname><given-names>E. L.</given-names></name><name xml:lang="ru"><surname>Дронова</surname><given-names>Е. Л.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow, 115478</p></bio><bio xml:lang="ru"><p>115478, Москва, Каширское шоссе, 24</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Alieva</surname><given-names>S. B.</given-names></name><name xml:lang="ru"><surname>Алиева</surname><given-names>С. Б.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow, 115478</p></bio><bio xml:lang="ru"><p>115478, Москва, Каширское шоссе, 24</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Allakhverdieva</surname><given-names>G. F.</given-names></name><name xml:lang="ru"><surname>Аллахвердиева</surname><given-names>Г. Ф.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow, 115478</p></bio><bio xml:lang="ru"><p>115478, Москва, Каширское шоссе, 24</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin Russian Cancer Research Center at the Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Российский онкологический научный центр им. Н.Н. Блохина» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2016-06-23" publication-format="electronic"><day>23</day><month>06</month><year>2016</year></pub-date><volume>6</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>35</fpage><lpage>41</lpage><history><date date-type="received" iso-8601-date="2016-06-22"><day>22</day><month>06</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-06-22"><day>22</day><month>06</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2016, Kropotov M.A., Yakovleva L.P., Dronova E.L., Alieva S.B., Allakhverdieva G.F.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2016, Кропотов М.А., Яковлева Л.П., Дронова Е.Л., Алиева С.Б., Аллахвердиева Г.Ф.</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="en">Kropotov M.A., Yakovleva L.P., Dronova E.L., Alieva S.B., Allakhverdieva G.F.</copyright-holder><copyright-holder xml:lang="ru">Кропотов М.А., Яковлева Л.П., Дронова Е.Л., Алиева С.Б., Аллахвердиева Г.Ф.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/206">https://ogsh.abvpress.ru/jour/article/view/206</self-uri><abstract xml:lang="en"><p>The article contains information about current trends of treatment of the locally advanced oropharynx cancer. We analyzed the results of chemoradiation treatment, and surgery treatment of patients with rudimentary tumors after the chemoradiation therapy, taking into account the tumor margin, which gives capacity to perform an adequate operation with good oncological results.</p></abstract><trans-abstract xml:lang="ru"><p>В статье представлены основные современные методы комплексного лечения рака слизистой оболочки ротоглотки; проводится анализ результатов химиолучевого лечения местно-распространенных форм рака ротоглотки, выполнения трансоральных резекций ротоглотки и применения хирургического лечения по поводу остаточной опухоли после химиолучевого лечения первично нерезектабельных опухолей. В настоящей работе обсуждается вопрос возможности выполнения хирургического вмешательства после проведения химиолучевого лечения с учетом границ остаточной опухоли, которое позволяет проводить адекватное хирургическое вмешательство с хорошими онкологическими результатами.</p></trans-abstract><kwd-group xml:lang="en"><kwd>locally advanced oropharynx cancer</kwd><kwd>chemoradiation treatment</kwd><kwd>transoral surgery</kwd><kwd>rudimentary tumors</kwd><kwd>tumor margin</kwd><kwd>volume of surgery for residual tumors of the oropharynx</kwd><kwd>results of treatment of the oropharynx</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>местно-распространенный рак ротоглотки</kwd><kwd>химиолучевое лечение</kwd><kwd>трансоральная резекция ротоглотки</kwd><kwd>остаточная опухоль</kwd><kwd>границы резекции</kwd><kwd>объем операции при остаточной опухоли ротоглотки</kwd><kwd>результаты лечения ротоглотки</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. 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