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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">21</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2013-0-4-15-19</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОРНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">ROLE OF INTAOPERATIVE ULTRASOUND INVESTIGATION IN SURGICAL TREATMENT OF THYROID CARCINOMA (A REVIEW OF LITERATURE)</article-title><trans-title-group xml:lang="ru"><trans-title>РОЛЬ ИНТРАОПЕРАЦИОННОГО УЛЬТРАЗВУКОВОГО ИССЛЕДОВАНИЯ В ХИРУРГИЧЕСКОМ ЛЕЧЕНИИ РАКА ЩИТОВИДНОЙ ЖЕЛЕЗЫ (ОБЗОР ЛИТЕРАТУРЫ)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Alymov</surname><given-names>Yu. V.</given-names></name><name xml:lang="ru"><surname>Алымов</surname><given-names>Ю. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>allmedperevod@gmail.com</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sholokhov</surname><given-names>V. N.</given-names></name><name xml:lang="ru"><surname>Шолохов</surname><given-names>В. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Podvyaznikov</surname><given-names>S. O.</given-names></name><name xml:lang="ru"><surname>Подвязников</surname><given-names>С. О.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N. N. Blokhin  Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow</institution></aff><aff><institution xml:lang="ru">ФГБНУ «Российский онкологический научный центр им. Н.Н. Блохина» РАМН, Москва</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Russian Medical Academy of Postgraduate Education, Moscow</institution></aff><aff><institution xml:lang="ru">ГБОУ ДПО «Российская медицинская академия последипломного образования» Минздрава России, Москва</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2013</year></pub-date><volume>3</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>15</fpage><lpage>19</lpage><history><date date-type="received" iso-8601-date="2015-04-15"><day>15</day><month>04</month><year>2015</year></date><date date-type="accepted" iso-8601-date="2015-04-15"><day>15</day><month>04</month><year>2015</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, Alymov Y.V., Sholokhov V.N., Podvyaznikov S.O.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, Алымов Ю.В., Шолохов В.Н., Подвязников С.О.</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">Alymov Y.V., Sholokhov V.N., Podvyaznikov S.O.</copyright-holder><copyright-holder xml:lang="ru">Алымов Ю.В., Шолохов В.Н., Подвязников С.О.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/21">https://ogsh.abvpress.ru/jour/article/view/21</self-uri><abstract xml:lang="en"><p>Head and neck cancers, including thyroid carcinomas, are characterized by high risk of metastasizing in regional lymph nodes. Lymph nodes status determines treatment of thyroid cancer as well as disease prognosis. Excision of affected lymph nodes is associated with risk reduction of relapse and reduction of mortality. However surgical treatment can be associated with some difficulties. Due to technologic progress modern ultrasonographs offer the possibility to visualize minimal tumor nodes (5–10 mm), which are characterized with complexity of localization during surgical manipulation, particularly in patients with relapses, that previously passed treatment (surgery and/or radiation therapy). These lymph nodes can be missed during surgical treatment, which will lead to reduction of treatment efficacy. The paper details utility of intraoperative ultrasound investigation as a method of obtaining information about localization of nonpalpable tumor nodes, cancer extension, reduction the possibility of non-radical surgical treatment and unnecessary extension of surgical treatment in patients with thyroid cancers, characterized with regional lymph nodes involvement.</p></abstract><trans-abstract xml:lang="ru"><p/></trans-abstract><kwd-group xml:lang="en"><kwd>thyroid cancer</kwd><kwd>regional lymph nodes involvement</kwd><kwd>relapse</kwd><kwd>surgical treatment</kwd><kwd>intraoperative ultrasound investigation</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак щитовидной железы</kwd><kwd>поражение регионарных лимфатических узлов</kwd><kwd>рецидив</kwd><kwd>хирургическое лечение</kwd><kwd>интраоперационное ультразвуковое исследование</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Онкология. Справочник практического врача. Под ред. И.В. Поддубной. М.: МЕД-пресс-информ, 2009. С. 163.</mixed-citation><mixed-citation xml:lang="ru">Онкология. Справочник практического врача. Под ред. И.В. Поддубной. М.: МЕД-пресс-информ, 2009. С. 163.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">2. Пачес А.И. Опухоли головы и шеи. М.: Медицина, 1997.</mixed-citation><mixed-citation xml:lang="ru">Пачес А.И. Опухоли головы и шеи. М.: Медицина, 1997.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">3. Snow G.В., Patel P., Leemans C.R., Tiwari R. Management of cervical lymph nodes in patients with head and neck cancer. Eur Arch Otorhinolaryngol 1992;249(4):187–94.</mixed-citation><mixed-citation xml:lang="ru">Snow G.В., Patel P., Leemans C.R., Tiwari R. Management of cervical lymph nodes in patients with head and neck cancer. Eur Arch Otorhinolaryngol 1992;249(4):187–94.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">4. Cooper D.S., Doherty G.M., Haugen B.R. et al. Management guidelines for patients with thyroid nodules and differenti ated thyroid cancer. Thyroid 2006;16:109–42.</mixed-citation><mixed-citation xml:lang="ru">Cooper D.S., Doherty G.M., Haugen B.R. et al. Management guidelines for patients with thyroid nodules and differenti ated thyroid cancer. Thyroid 2006;16:109–42.</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">5. Kouvaraki M.A., Shapiro S.E., Fornage B.D. et al. Role of pre operative ultrasonography in the surgical management of patients with thyroid cancer. Surgery 2003;134:946–54; discussion 954–5.</mixed-citation><mixed-citation xml:lang="ru">Kouvaraki M.A., Shapiro S.E., Fornage B.D. et al. Role of pre operative ultrasonography in the surgical management of patients with thyroid cancer. Surgery 2003;134:946–54; discussion 954–5.</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">6. Stulak J.M., Grant C.S., Farley D.R. et al. Value of preopera tive ultrasonography in the surgical management of ini tial and reoperative papillary thyroid cancer. Arch Surg 2006;141:489–94; discussion 494–6.</mixed-citation><mixed-citation xml:lang="ru">Stulak J.M., Grant C.S., Farley D.R. et al. Value of preopera tive ultrasonography in the surgical management of ini tial and reoperative papillary thyroid cancer. Arch Surg 2006;141:489–94; discussion 494–6.</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">7. Аллахвердиева Г.Ф., Синюкова Г.Т., Шолохов В.Н., Романов И.С. Возможности комплексного ультразвукового исследования в диагностике метастатического поражения лимфатических узлов шеи. Ультразвуковая и функциональная диагностика 2005;1:18–22.</mixed-citation><mixed-citation xml:lang="ru">Аллахвердиева Г.Ф., Синюкова Г.Т., Шолохов В.Н., Романов И.С. Возможности комплексного ультразвукового исследования в диагностике метастатического поражения лимфатических узлов шеи. Ультразвуковая и функциональная диагностика 2005;1:18–22.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">8. Чиссов В.И., Трофимова Е.Ю. Ультразвуковое исследование лимфатических узлов в онкологии. Практическое руководство. М.: ООО «Фирма «Стром», 2003. С. 37, 66, 72, 73.</mixed-citation><mixed-citation xml:lang="ru">Чиссов В.И., Трофимова Е.Ю. Ультразвуковое исследование лимфатических узлов в онкологии. Практическое руководство. М.: ООО «Фирма «Стром», 2003. С. 37, 66, 72, 73.</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">9. Biggar M., Wong C., Law M., Bennett I.C. Intraoperative ultrasound-guided excision of cervical lymph nodes for recurrent differentiated thyroid cancer. World J Endoc Surg 2013;5(2):45–9.</mixed-citation><mixed-citation xml:lang="ru">Biggar M., Wong C., Law M., Bennett I.C. Intraoperative ultrasound-guided excision of cervical lymph nodes for recurrent differentiated thyroid cancer. World J Endoc Surg 2013;5(2):45–9.</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">10. Asteria C., Giovanardi A., Pizzocaro A. et al. US-elastography in the differential diagnosis of benign and malignant thyroid nodules. Thyroid 2008;18:523–31.</mixed-citation><mixed-citation xml:lang="ru">Asteria C., Giovanardi A., Pizzocaro A. et al. US-elastography in the differential diagnosis of benign and malignant thyroid nodules. Thyroid 2008;18:523–31.</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">11. Agcaoglu O., Aliyev S., Taskin E.H. et al. The Utility of Intraoperative Ultrasound in Modified Radical Neck Dissection: A Pilot Study. Surg Innov 2013 May 20.</mixed-citation><mixed-citation xml:lang="ru">Agcaoglu O., Aliyev S., Taskin E.H. et al. The Utility of Intraoperative Ultrasound in Modified Radical Neck Dissection: A Pilot Study. Surg Innov 2013 May 20.</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">12. Kang T.W., Shin J.H., Han B.K. et al. Preoperative ultrasound-guided tattooing localization of recurrences after thyroidectomy: safety and effectiveness. Ann Surg Oncol 2009 Jun;16(6):1655–9.</mixed-citation><mixed-citation xml:lang="ru">Kang T.W., Shin J.H., Han B.K. et al. Preoperative ultrasound-guided tattooing localization of recurrences after thyroidectomy: safety and effectiveness. Ann Surg Oncol 2009 Jun;16(6):1655–9.</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">13. Lucchini R., Puxeddu E., Calzolari F. et al. Recurrences of thyroid well differentiated cancer: ultrasonography-guided surgical treatment. Minerva Chir 2008 Aug;63(4):257–60.</mixed-citation><mixed-citation xml:lang="ru">Lucchini R., Puxeddu E., Calzolari F. et al. Recurrences of thyroid well differentiated cancer: ultrasonography-guided surgical treatment. Minerva Chir 2008 Aug;63(4):257–60.</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">14. O’Connell K., Yen T.W., Quiroz F. et al. The utility of routine preoperative cervical ultrasonography in patients undergoing thyroidectomy for differentiated thyroid cancer. Surgery 2013 Oct;154(4):697–701; discussion 701–3.</mixed-citation><mixed-citation xml:lang="ru">O’Connell K., Yen T.W., Quiroz F. et al. The utility of routine preoperative cervical ultrasonography in patients undergoing thyroidectomy for differentiated thyroid cancer. Surgery 2013 Oct;154(4):697–701; discussion 701–3.</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">15. Ryan W.R., Orloff L.A. Intraoperative tumor localization with surgeon-performed ultrasound-guided needle dye injection. Laryngoscope 2011 Aug;121(8):1651–5.</mixed-citation><mixed-citation xml:lang="ru">Ryan W.R., Orloff L.A. Intraoperative tumor localization with surgeon-performed ultrasound-guided needle dye injection. Laryngoscope 2011 Aug;121(8):1651–5.</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">16. Sippel R.S., Elaraj D.M., Poder L. et al. Localization of recurrent thyroid cancer using intraoperative ultrasound-guided dye injection. World J Surg 2009 Mar;33(3):434–9.</mixed-citation><mixed-citation xml:lang="ru">Sippel R.S., Elaraj D.M., Poder L. et al. Localization of recurrent thyroid cancer using intraoperative ultrasound-guided dye injection. World J Surg 2009 Mar;33(3):434–9.</mixed-citation></citation-alternatives></ref></ref-list></back></article>
