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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">217</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2016-6-3-22-32</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DIAGNOSIS AND TREATMENT OF HEAD AND NECK TUMORS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ ГОЛОВЫ И ШЕИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Basic principles of managing radiation and drug induced mucositis and dermatitis for oropharyngeal squamouscell carcinoma</article-title><trans-title-group xml:lang="ru"><trans-title>Основные принципы ведения пациентов с мукозитом и дерматитом при лучевом лечении с лекарственной модификацией больных плоскоклеточным раком орофарингеальной области</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gevorkov</surname><given-names>A. R.</given-names></name><name xml:lang="ru"><surname>Геворков</surname><given-names>А. Р.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinskiy Passage, Moscow, 125284</p></bio><bio xml:lang="ru"><p>125284, Москва, 2-й Боткинский проезд, 3</p></bio><email>torsurg@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Boykо</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Бойко</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinskiy Passage, Moscow, 125284</p></bio><bio xml:lang="ru"><p>125284, Москва, 2-й Боткинский проезд, 3</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bolotinа</surname><given-names>L. V.</given-names></name><name xml:lang="ru"><surname>Болотина</surname><given-names>Л. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinskiy Passage, Moscow, 125284</p></bio><bio xml:lang="ru"><p>125284, Москва, 2-й Боткинский проезд, 3</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shashkov</surname><given-names>S. V.</given-names></name><name xml:lang="ru"><surname>Шашков</surname><given-names>С. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinskiy Passage, Moscow, 125284</p></bio><bio xml:lang="ru"><p>125284, Москва, 2-й Боткинский проезд, 3</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">P.A. Herzen Moscow Oncology Research Institute – Branch of National Medical Radiology Research Center at the Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">Московский научно-исследовательский онкологический институт им. П.А. Герцена – филиал ФГБУ «Национальный медицинский исследовательский радиологический центр» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2016-10-21" publication-format="electronic"><day>21</day><month>10</month><year>2016</year></pub-date><volume>6</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>12</fpage><lpage>21</lpage><history><date date-type="received" iso-8601-date="2016-10-21"><day>21</day><month>10</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-10-21"><day>21</day><month>10</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2016, Gevorkov A.R., Boykо A.V., Bolotinа L.V., Shashkov S.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2016, Геворков А.Р., Бойко А.В., Болотина Л.В., Шашков С.В.</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="en">Gevorkov A.R., Boykо A.V., Bolotinа L.V., Shashkov S.V.</copyright-holder><copyright-holder xml:lang="ru">Геворков А.Р., Бойко А.В., Болотина Л.В., Шашков С.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/217">https://ogsh.abvpress.ru/jour/article/view/217</self-uri><abstract xml:lang="en"><p>The work illustrates main issues of the radial treatment acceptability with the modification of patients with the squamous cell carcinoma of the oropharyngeal area. The spectrum of side effects is given and key issues of the accompanying therapy are concerned. Separately are given approaches to the treatment of patients with radial mucositis and dermatitis. </p></abstract><trans-abstract xml:lang="ru"><p>В работе освещены основные вопросы переносимости лучевого лечения с модификацией пациентов с плоскоклеточным орофарингеальным раком. Представлен спектр побочных эффектов и затронуты ключевые вопросы терапии сопровождения. Отдельно изложены подходы к ведению больных с лучевым мукозитом и дерматитом. </p></trans-abstract><kwd-group xml:lang="en"><kwd>squamous cell carcinoma</kwd><kwd>head and neck tumors</kwd><kwd>radiotherapy</kwd><kwd>radition mucositis</kwd><kwd>radition dermatitis</kwd><kwd>chemoradiotherapy</kwd><kwd>target modification</kwd><kwd>Cetuximab</kwd><kwd>quality of life</kwd><kwd>supportive treatment</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>плоскоклеточный рак</kwd><kwd>опухоли головы и шеи</kwd><kwd>лучевая терапия</kwd><kwd>лучевой мукозит</kwd><kwd>лучевой дерматит</kwd><kwd>химиолучевая терапия</kwd><kwd>таргетная модификация</kwd><kwd>цетуксимаб</kwd><kwd>качество жизни</kwd><kwd>сопроводительная терапия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. The Global Burden of Cancer 2013. Global Burden of Disease Cancer Collaboration. 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