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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">218</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2016-6-3-22-26</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DIAGNOSIS AND TREATMENT OF HEAD AND NECK TUMORS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ ГОЛОВЫ И ШЕИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">The use of Kuraderm drug in the treatment of basal cell carcinoma of the head and neck</article-title><trans-title-group xml:lang="ru"><trans-title>Опыт применения препарата Курадерм в лечении базально-клеточного рака кожи головы и шеи</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Dobrokhotova</surname><given-names>V. Z.</given-names></name><name xml:lang="ru"><surname>Доброхотова</surname><given-names>В. З.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>8 Trubetskaya St., Moscow, 119991</p></bio><bio xml:lang="ru"><p>119991, Москва, ул. М. Трубецкая, 8</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Batsev</surname><given-names>A. F.</given-names></name><name xml:lang="ru"><surname>Бацев</surname><given-names>А. Ф.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow, 115478</p></bio><bio xml:lang="ru"><p>115478, Москва, Каширское шоссе, 24</p></bio><email>batsevhph@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Belysheva</surname><given-names>T. S.</given-names></name><name xml:lang="ru"><surname>Белышева</surname><given-names>Т. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow, 115478</p></bio><bio xml:lang="ru"><p>115478, Москва, Каширское шоссе, 24</p></bio><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Department of Urology of the Sechenov First Moscow State Medical University</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">N.N. Blokhin Russian Cancer Research Center, Ministry ofHealth of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Российский онкологический научный центр им. Н.Н. Блохина» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2016-10-21" publication-format="electronic"><day>21</day><month>10</month><year>2016</year></pub-date><volume>6</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>22</fpage><lpage>26</lpage><history><date date-type="received" iso-8601-date="2016-10-21"><day>21</day><month>10</month><year>2016</year></date><date date-type="accepted" iso-8601-date="2016-10-21"><day>21</day><month>10</month><year>2016</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2016, Dobrokhotova V.Z., Batsev A.F., Belysheva T.S.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2016, Доброхотова В.З., Бацев А.Ф., Белышева Т.С.</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="en">Dobrokhotova V.Z., Batsev A.F., Belysheva T.S.</copyright-holder><copyright-holder xml:lang="ru">Доброхотова В.З., Бацев А.Ф., Белышева Т.С.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/218">https://ogsh.abvpress.ru/jour/article/view/218</self-uri><abstract xml:lang="en"><p>Basal cell carcinoma is one of the most common malignancies. Despite a wide range of treatment options and relatively good prognosis of the disease, there may be restrictions on the use of standard methods of treatment because of elderly patients, their physical condition and characteristics of the tumor localization. We provide clinical examples of successful treatment of basal cell carcinoma of the head and neck with Kuraderm BEC5. This is a drug with anti-tumor activity for topical use made on the basis of glycoalkaloids of plants of nightshade family. </p></abstract><trans-abstract xml:lang="ru"><p>Базально-клеточный рак кожи является одним из наиболее часто встречающихся злокачественных новообразований. Несмотря на большой спектр лечебных возможностей и относительно благоприятный прогноз данного заболевания, могут возникать ограничения в применении стандартных методов лечения — из-за пожилого возраста пациентов, их соматического состояния и особенностей локализации опухоли. Приведены клинические примеры успешного лечения базально-клеточного рака головы и шеи препаратом с противоопухолевой активностью для наружного применения на основе гликоалкалоидов растений семейства пасленовых Курадерм BEC5. </p></trans-abstract><kwd-group xml:lang="en"><kwd>basal-cell carcinoma</kwd><kwd>carcinoma of the head and neck</kwd><kwd>Kuraderm</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>базально-клеточный рак кожи</kwd><kwd>рак кожи головы и шеи</kwd><kwd>Курадерм</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Злокачественные новообразования в России в 2013 году (заболеваемость и смертность). Под ред. А.Д. Каприна, В.В. Старинского, Г.В. Петровой. М., 2015. [Malignant neoplasms in Russia in 2013 (morbidity and mortality rate). By eds.: A.D. Kaprin, V.V. Starinskiy, G.V. Petrova. Мoscow, 2015. 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