Head and Neck TumorsHead and Neck TumorsОпухоли головы и шеи2222-14682411-4634Publishing House ABV Press23210.17650/2222-1468-2017-7-1-26-30DIAGNOSIS AND TREATMENT OF HEAD AND NECK TUMORSДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ ГОЛОВЫ И ШЕИRecurrence and local lymphogenic metastasis of conjunctival melanomaРецидивирование и локальное лимфогенное метастазирование меланомы конъюнктивыAndreychenkoA. M.АндрейченкоА. М.
Russian Federation

7 Mamonovskiy Lane, Moscow 123001, Russia

Россия, 123001 Москва, Мамоновский пер., 7

visus.ou@gmail.comMozhaevaT. A.МожаеваТ. А.
Russian Federation

2/1 Barrikadnaya St., Moscow 125993, Russia

Россия, 125993 Москва, ул. Баррикадная, 2/1

S.P. Botkin City Clinical Hospital Branch # 1 “Ophthalmology In-Patient Clinic”, Department of Healthcare of MoscowФилиал № 1 «Офтальмологический стационар» ГБУЗ «Городская клиническая больница им. С.П. Боткина Департамента здравоохранения г. Москвы»Russian Medical Academy of Continuous Professional Education at the Ministry of Health of RussiaФГБОУ ДПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России020420177126300204201702042017Copyright ©; 2017, Andreychenko A.M., Mozhaeva T.A.Copyright ©; 2017, Андрейченко А.М., Можаева Т.А.2017Andreychenko A.M., Mozhaeva T.A.Андрейченко А.М., Можаева Т.А.https://creativecommons.org/licenses/by/4.0https://ogsh.abvpress.ru/jour/article/view/232

Objective. Study of local lymphogenic metastasis (inside the conjunctiva) of conjunctival melanoma.

Introduction. Conjunctiva is a transparent mucous membrane with a large number of blood vessels. Normally, it contains melanocytes which explains possibility of development of pigmented tumors in the conjunctiva. Conjunctival melanoma is a rare tumor:it constitutes about 1–3 % of all malignant tumors of the ocular adnexa, and according to different authors its incidence rate is 0.02–0.08 for 100 thousand people. Melanoma is characterized by frequent recurrences and hematogenic and lymphogenic metastases.

Materials and methods. Fifteen (15) patients with conjunctival melanoma were included in the study. Tumor recurrence and/or tumor seeding were reasons for inclusion in the study. For graphic representation of tumor localization, we developed a diagram of the conjunctival surface which subsequently was improved using a diagram of lymphatic vessels of the bulbar conjunctiva. An interpretive map of the conjunctival surface produced this way was taking into account lymph node structure of the bulbar conjunctiva.

Results and discussion. Recurrence was observed only in 4 of 15 patients. Seedings were usually localized in neighboring or distant areas in respect to the primary lesion localization, which, supposedly, can be explained by the structure of conjunctival lymphatic system.

Conclusion. In one third of the cases (in 5 of 15 patients) primary tumors were localized near large lymphatic vessels. Moreover, in all cases seeding was observed near the same lymphatic collectors, but at a distance from the primary lesion localization. This confirms possibility of local metastasis through conjunctival lymphatic paths.

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