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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">236</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2017-7-1-50-60</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DIAGNOSIS AND TREATMENT OF HEAD AND NECK TUMORS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ ГОЛОВЫ И ШЕИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Nutritional support as an obligatory component of accompanying therapy for head and neck tumors during radiotherapy and chemoradiotherapy</article-title><trans-title-group xml:lang="ru"><trans-title>Нутритивная поддержка как обязательный компонент терапии сопровождения при лучевом и химиолучевом лечении больных с опухолями головы и шеи</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Boyko</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Бойко</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Beam Therapy Modification</p><p>3 2nd Botkinskiy proezd, Moscow 125284, Russia</p></bio><bio xml:lang="ru"><p>Отделение лучевой терапии с модификацией</p><p>Россия, 125284 Москва, 2-й Боткинский пр-д, 3</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gevorkov</surname><given-names>A. R.</given-names></name><name xml:lang="ru"><surname>Геворков</surname><given-names>А. Р.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Beam Therapy Modification</p><p>3 2nd Botkinskiy proezd, Moscow 125284, Russia</p></bio><bio xml:lang="ru"><p>Отделение лучевой терапии с модификацией</p><p>Россия, 125284 Москва, 2-й Боткинский пр-д, 3</p></bio><email>dr.gevorkov@gmail.com</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Volkova</surname><given-names>E. E.</given-names></name><name xml:lang="ru"><surname>Волкова</surname><given-names>Е. Э.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>26th km of the Baltiya highway, Krasnogorsk Region, Moscow Region 143421, Russia</p></bio><bio xml:lang="ru"><p>Россия, 143421 МО, Красногорский район, 26-й км автодороги «Балтия», БЦ «Рига Лэнд», блок В</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Shashkov</surname><given-names>S. V.</given-names></name><name xml:lang="ru"><surname>Шашков</surname><given-names>С. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Beam Therapy Modification</p><p>3 2nd Botkinskiy proezd, Moscow 125284, Russia</p></bio><bio xml:lang="ru"><p>Отделение лучевой терапии с модификацией</p><p>Россия, 125284 Москва, 2-й Боткинский пр-д, 3</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">Московский научно-исследовательский онкологический институт им. П.А. Герцена – филиала ФГБУ «Национальный медицинский исследовательский радиологический центр» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Nutricia Advance, block V, Business Center “Riga-Land”</institution></aff><aff><institution xml:lang="ru">ООО «Нутриция Эдванс»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-04-02" publication-format="electronic"><day>02</day><month>04</month><year>2017</year></pub-date><volume>7</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>50</fpage><lpage>60</lpage><history><date date-type="received" iso-8601-date="2017-04-02"><day>02</day><month>04</month><year>2017</year></date><date date-type="accepted" iso-8601-date="2017-04-02"><day>02</day><month>04</month><year>2017</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Boyko A.V., Gevorkov A.R., Volkova E.E., Shashkov S.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, Бойко А.В., Геворков А.Р., Волкова Е.Э., Шашков С.В.</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Boyko A.V., Gevorkov A.R., Volkova E.E., Shashkov S.V.</copyright-holder><copyright-holder xml:lang="ru">Бойко А.В., Геворков А.Р., Волкова Е.Э., Шашков С.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/236">https://ogsh.abvpress.ru/jour/article/view/236</self-uri><abstract xml:lang="en"><p>The article considers supportive therapy in patients with head and neck tumors during radiotherapy and chemoradiotherapy. Special attention is given to nutritional support on every stage of patient care. The main methods of evaluation of nutritional status and risks are presented, as well as principles of clinical nutrition selection.</p></abstract><trans-abstract xml:lang="ru"><p>Публикация посвящена вопросам терапии сопровождения при лучевом и химиолучевом лечении больных с опухолями головы и шеи. Особое внимание уделено роли нутритивной поддержки на всех этапах ведения пациентов. Представлены основные методы оценки нутритивного статуса и рисков, а также принципы выбора вариантов лечебного питания.</p></trans-abstract><kwd-group xml:lang="en"><kwd>head and neck tumors</kwd><kwd>nutritional deficiency</kwd><kwd>chemoradiotherapy</kwd><kwd>supportive therapy</kwd><kwd>quality of life</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>опухоли головы и шеи</kwd><kwd>нутритивная недостаточность</kwd><kwd>химиолучевая терапия</kwd><kwd>терапия сопровождения</kwd><kwd>качество жизни больных</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Состояние онкологической помощи населению России в 2015 году. Под ред. А.Д. Каприна, В.В. Старинского, Г.В. Петровой. М.: МНИОИ им. П.А. Герцена – филиал ФГБУ «НМИРЦ» Минздрава России, 2016. [State of oncological care in Russia in 2015. Editors: A.D. Kaprin, V.V. Starinskiy, G.V. Petrova. Moscow: MNIOI imeni P.A. Hertzena – filial FGBU “NMIRC” Minzdrava Rossii, 2016. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Состояние онкологической помощи населению России в 2015 году. Под ред. А.Д. Каприна, В.В. Старинского, Г.В. Петровой. М.: МНИОИ им. П.А. Герцена – филиал ФГБУ «НМИРЦ» Минздрава России, 2016. [State of oncological care in Russia in 2015. Editors: A.D. Kaprin, V.V. Starinskiy, G.V. Petrova. Moscow: MNIOI imeni P.A. Hertzena – filial FGBU “NMIRC” Minzdrava Rossii, 2016. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">2. The Global Burden of Cancer 2015. Global Burden of Disease Cancer Collaboration. JAMA Oncol. Published online December 3, 2016. http://jamanetwork.com/journals/jamaoncology/article-abstract/2588797</mixed-citation><mixed-citation xml:lang="ru">The Global Burden of Cancer 2015. Global Burden of Disease Cancer Collaboration. JAMA Oncol. Published online December 3, 2016. http://jamanetwork.com/journals/jamaoncology/article-abstract/2588797</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">3. Radiation Oncology: An Evidence-Based Approach. Ed. by J.J. Lu, L.W. Brady. New York: Springer, 2008.</mixed-citation><mixed-citation xml:lang="ru">Radiation Oncology: An Evidence-Based Approach. Ed. by J.J. Lu, L.W. Brady. New York: Springer, 2008.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">4. Pignon J.P., le Maître A., Maillard E., Bourhis J. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients. Rad Oncol 2009:92;4–14. DOI: 10.1016/j.radonc.2009.04.014. PMID: 19446902.</mixed-citation><mixed-citation xml:lang="ru">Pignon J.P., le Maître A., Maillard E., Bourhis J. Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients. Rad Oncol 2009:92;4–14. DOI: 10.1016/j.radonc.2009.04.014. PMID: 19446902.</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">5. Handbook of Evidence-Based Radiation Oncology. By eds.: E.K. Hansen Roach III Mack. Springer, 2010.</mixed-citation><mixed-citation xml:lang="ru">Handbook of Evidence-Based Radiation Oncology. By eds.: E.K. Hansen Roach III Mack. Springer, 2010.</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">6. Adelstein D.J., Li Y., Adams G.L. et al. An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer. J Clin Oncol 2003;21(1):92–8. DOI: 10.1200/JCO.2003.01.008. PMID: 12506176.</mixed-citation><mixed-citation xml:lang="ru">Adelstein D.J., Li Y., Adams G.L. et al. An intergroup phase III comparison of standard radiation therapy and two schedules of concurrent chemoradiotherapy in patients with unresectable squamous cell head and neck cancer. J Clin Oncol 2003;21(1):92–8. DOI: 10.1200/JCO.2003.01.008. PMID: 12506176.</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">7. Pignon J.P., Bourhis J., Domenge C., Designé L. Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three metaanalyses of updated individual data. MACH-NC Collaborative Group. Meta- Analysis of Chemotherapy on Head and Neck Cancer. Lancet 2000;355(9208):949–55. PMID: 10768432.</mixed-citation><mixed-citation xml:lang="ru">Pignon J.P., Bourhis J., Domenge C., Designé L. Chemotherapy added to locoregional treatment for head and neck squamous-cell carcinoma: three metaanalyses of updated individual data. MACH-NC Collaborative Group. Meta- Analysis of Chemotherapy on Head and Neck Cancer. Lancet 2000;355(9208):949–55. PMID: 10768432.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">8. Bourhis J., Amand C., Pignon J.P. Update of MACH-NC (Meta-Analysis of Chemotherapy in Head &amp; Neck Cancer) database focused on concomitant chemoradiotherapy. J Clin Oncol, ASCO Annual Meeting Proceedings (Post-Meeting Edition) 2004;22:5505.</mixed-citation><mixed-citation xml:lang="ru">Bourhis J., Amand C., Pignon J.P. Update of MACH-NC (Meta-Analysis of Chemotherapy in Head &amp; Neck Cancer) database focused on concomitant chemoradiotherapy. J Clin Oncol, ASCO Annual Meeting Proceedings (Post-Meeting Edition) 2004;22:5505.</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">9. Calais G., Alfonsi M., Bardet E. et al. Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma. J Natl Cancer Inst 1999;91(24):2081–6. PMID: 10601378.</mixed-citation><mixed-citation xml:lang="ru">Calais G., Alfonsi M., Bardet E. et al. Randomized trial of radiation therapy versus concomitant chemotherapy and radiation therapy for advanced-stage oropharynx carcinoma. J Natl Cancer Inst 1999;91(24):2081–6. PMID: 10601378.</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">10. Brizel D.M., Albers M.E., Fisher S.R. et al. Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer. N Engl J Med 1998;338(25):1798–804.</mixed-citation><mixed-citation xml:lang="ru">Brizel D.M., Albers M.E., Fisher S.R. et al. Hyperfractionated irradiation with or without concurrent chemotherapy for locally advanced head and neck cancer. N Engl J Med 1998;338(25):1798–804.</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">11. Posner M.R., Hershock D., Le Lann L. et al. TAX 324: A phase III trial at TPF vs. PF induction chemotherapy followed chemoradiotherapy in locally advanced SCCHN. Paper presented at American Society of Clinical Oncology (ASCO) annual meeting, Atlanta GA, 2006.</mixed-citation><mixed-citation xml:lang="ru">Posner M.R., Hershock D., Le Lann L. et al. TAX 324: A phase III trial at TPF vs. PF induction chemotherapy followed chemoradiotherapy in locally advanced SCCHN. Paper presented at American Society of Clinical Oncology (ASCO) annual meeting, Atlanta GA, 2006.</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">12. Scully С., Epstein J., Sonis S. Oral mucositis: a challenging complication of radiotherapy, chemotherapy and radiochemotherapy. Part 2: diagnosis and management of mucositis. Head Neck 2004;26(1):77–84. DOI: 10.1002/hed.10326. PMID: 14724910.</mixed-citation><mixed-citation xml:lang="ru">Scully С., Epstein J., Sonis S. Oral mucositis: a challenging complication of radiotherapy, chemotherapy and radiochemotherapy. Part 2: diagnosis and management of mucositis. Head Neck 2004;26(1):77–84. DOI: 10.1002/hed.10326. PMID: 14724910.</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">13. Argiris A., Brockstein B.E., Haraf D.J. et al. Competing causes of death and second primary tumors in patients with locoregionally advanced head and neck cancer treated with chemoradiotherapy. Clin Cancer Res 2004;10:1956–62. DOI: 10.1158/1078-0432.CCR-03- 1077. PMID: 15041712.</mixed-citation><mixed-citation xml:lang="ru">Argiris A., Brockstein B.E., Haraf D.J. et al. Competing causes of death and second primary tumors in patients with locoregionally advanced head and neck cancer treated with chemoradiotherapy. Clin Cancer Res 2004;10:1956–62. DOI: 10.1158/1078-0432.CCR-03- 1077. PMID: 15041712.</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">14. Epstein J.B., Thariat J., Bensadoun R.J. et al. Oral complications of cancer and cancer therapy: from cancer treatment to survivorship. CA Cancer J Clin 2012;62(6):400–22. DOI: 10.3322/caac.21157. PMID: 22972543.</mixed-citation><mixed-citation xml:lang="ru">Epstein J.B., Thariat J., Bensadoun R.J. et al. Oral complications of cancer and cancer therapy: from cancer treatment to survivorship. CA Cancer J Clin 2012;62(6):400–22. DOI: 10.3322/caac.21157. PMID: 22972543.</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">15. Kang H.S., Roh J.L., Lee S. et al. Noncancer-related health events and mortality in head and neck cancer patients after definitive radiotherapy: a prospective study. Medicine (Baltimore) 2016;95(19):e3403. DOI: 10.1097/MD.0000000000003403.</mixed-citation><mixed-citation xml:lang="ru">Kang H.S., Roh J.L., Lee S. et al. Noncancer-related health events and mortality in head and neck cancer patients after definitive radiotherapy: a prospective study. Medicine (Baltimore) 2016;95(19):e3403. DOI: 10.1097/MD.0000000000003403.</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">16. Bensinger W., Schubert M., Ang K.K. et al. NCCN Task Force Report. prevention and management of mucositis in cancer care. J Natl Compr Canc Netw 2008;6(Suppl 1):1– 21;quiz S22–4. PMID: 18289497.</mixed-citation><mixed-citation xml:lang="ru">Bensinger W., Schubert M., Ang K.K. et al. NCCN Task Force Report. prevention and management of mucositis in cancer care. J Natl Compr Canc Netw 2008;6(Suppl 1):1– 21;quiz S22–4. PMID: 18289497.</mixed-citation></citation-alternatives></ref><ref id="B17"><label>17.</label><citation-alternatives><mixed-citation xml:lang="en">17. Rosenthal D.I., Trotti A. Strategies for managing radiation-induced mucositis in head and neck cancer. Semin Radiat Oncol 2009;19:29–34. DOI: 10.1016/j.semradonc.2008.09.006. PMID: 19028343.</mixed-citation><mixed-citation xml:lang="ru">Rosenthal D.I., Trotti A. Strategies for managing radiation-induced mucositis in head and neck cancer. Semin Radiat Oncol 2009;19:29–34. DOI: 10.1016/j.semradonc.2008.09.006. PMID: 19028343.</mixed-citation></citation-alternatives></ref><ref id="B18"><label>18.</label><citation-alternatives><mixed-citation xml:lang="en">18. Trotti A., Bellm L.A., Epstein J.B. et al. Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy: A systematic literature review. Radiother Oncol 2003;66:253–62. DOI: 10.1016/S0167-8140(02)00404-8. PMID: 12742264.</mixed-citation><mixed-citation xml:lang="ru">Trotti A., Bellm L.A., Epstein J.B. et al. Mucositis incidence, severity and associated outcomes in patients with head and neck cancer receiving radiotherapy with or without chemotherapy: A systematic literature review. Radiother Oncol 2003;66:253–62. DOI: 10.1016/S0167-8140(02)00404-8. PMID: 12742264.</mixed-citation></citation-alternatives></ref><ref id="B19"><label>19.</label><citation-alternatives><mixed-citation xml:lang="en">19. Campos M.I., Campos C.N., Aarestrup F.M., Aarestrup B.J. Oral mucositis in cancer treatment: natural history, prevention and treatment. Mol Clin Oncol 2014;2,337–40. DOI: 10.3892/mco.2014.253 PMID: 24772297.</mixed-citation><mixed-citation xml:lang="ru">Campos M.I., Campos C.N., Aarestrup F.M., Aarestrup B.J. Oral mucositis in cancer treatment: natural history, prevention and treatment. Mol Clin Oncol 2014;2,337–40. DOI: 10.3892/mco.2014.253 PMID: 24772297.</mixed-citation></citation-alternatives></ref><ref id="B20"><label>20.</label><citation-alternatives><mixed-citation xml:lang="en">20. Zhu G., Lin J., Kim S. et al. Asian expert recommendation on management of skin and mucosal effects of radiation, with or without the addition of cetuximab or chemotherapy, in treatment of head and neck squamous cell carcinoma. BMC Cancer 2016;16:42. DOI: 10.1186/s12885-016-2073-z. PMID: PMC4730602.</mixed-citation><mixed-citation xml:lang="ru">Zhu G., Lin J., Kim S. et al. Asian expert recommendation on management of skin and mucosal effects of radiation, with or without the addition of cetuximab or chemotherapy, in treatment of head and neck squamous cell carcinoma. BMC Cancer 2016;16:42. DOI: 10.1186/s12885-016-2073-z. PMID: PMC4730602.</mixed-citation></citation-alternatives></ref><ref id="B21"><label>21.</label><citation-alternatives><mixed-citation xml:lang="en">21. NCCN Guidelines. Version 2.2016. Available at: www.nccn.org/professionals/physician_gls/pdf/head-and-neck.pdf.</mixed-citation><mixed-citation xml:lang="ru">NCCN Guidelines. Version 2.2016. Available at: www.nccn.org/professionals/physician_gls/pdf/head-and-neck.pdf.</mixed-citation></citation-alternatives></ref><ref id="B22"><label>22.</label><citation-alternatives><mixed-citation xml:lang="en">22. Vera-Llonch M., Oster G., Hagiwara M., Sonis S. Oral mucositis in patients undergoing radiation treatment for head and neck carcinoma. Cancer 2006;106:329–36. DOI: 10.1002/cncr.21622. PMID: 16342066.</mixed-citation><mixed-citation xml:lang="ru">Vera-Llonch M., Oster G., Hagiwara M., Sonis S. Oral mucositis in patients undergoing radiation treatment for head and neck carcinoma. Cancer 2006;106:329–36. DOI: 10.1002/cncr.21622. PMID: 16342066.</mixed-citation></citation-alternatives></ref><ref id="B23"><label>23.</label><citation-alternatives><mixed-citation xml:lang="en">23. Mortensen H.R., Overgaard J., Jensen K. et al. Factors associated with acute and late dysphagia in the DAHANCA 6 &amp; 7 randomized trial with accelerated radiotherapy for head and neck cancer. Acta Oncol 2013;52:1535–42. DOI: 10.3109/0284186X.2013.824609. PMID: 24047339.</mixed-citation><mixed-citation xml:lang="ru">Mortensen H.R., Overgaard J., Jensen K. et al. Factors associated with acute and late dysphagia in the DAHANCA 6 &amp; 7 randomized trial with accelerated radiotherapy for head and neck cancer. Acta Oncol 2013;52:1535–42. DOI: 10.3109/0284186X.2013.824609. PMID: 24047339.</mixed-citation></citation-alternatives></ref><ref id="B24"><label>24.</label><citation-alternatives><mixed-citation xml:lang="en">24. Barrera R. Nutritional support in cancer patients. J Parenter Enteral Nutr 2002;26(5):63– 71. DOI: 10.1177/014860710202600516. PMID: 12216725.</mixed-citation><mixed-citation xml:lang="ru">Barrera R. Nutritional support in cancer patients. J Parenter Enteral Nutr 2002;26(5):63– 71. DOI: 10.1177/014860710202600516. PMID: 12216725.</mixed-citation></citation-alternatives></ref><ref id="B25"><label>25.</label><citation-alternatives><mixed-citation xml:lang="en">25. Bloch A. Nutrition support in cancer. Semin Oncol Nurs 2000;16(2):122–7. DOI: 10.1053/on.2000.5555.</mixed-citation><mixed-citation xml:lang="ru">Bloch A. Nutrition support in cancer. Semin Oncol Nurs 2000;16(2):122–7. DOI: 10.1053/on.2000.5555.</mixed-citation></citation-alternatives></ref><ref id="B26"><label>26.</label><citation-alternatives><mixed-citation xml:lang="en">26. Bozzetti F., Gavazzi C., Miceli R. Perioperative total parenteral nutrition in malnourished, gastrointestinal cancer patients: a randomized, clinical trial. J Parenter Enteral Nutr 2000;24(1):7–14. DOI: 10.1177/014860710002400107. PMID: 10638466.</mixed-citation><mixed-citation xml:lang="ru">Bozzetti F., Gavazzi C., Miceli R. Perioperative total parenteral nutrition in malnourished, gastrointestinal cancer patients: a randomized, clinical trial. J Parenter Enteral Nutr 2000;24(1):7–14. DOI: 10.1177/014860710002400107. PMID: 10638466.</mixed-citation></citation-alternatives></ref><ref id="B27"><label>27.</label><citation-alternatives><mixed-citation xml:lang="en">27. Bozzetti F. Nutrition and gastrointestinal cancer. Curr Opin Clin Nutr Metab Care 2001;4(6):541–6. DOI: 10.1097/00075197-200111000-00014. PMID: 11706291.</mixed-citation><mixed-citation xml:lang="ru">Bozzetti F. Nutrition and gastrointestinal cancer. Curr Opin Clin Nutr Metab Care 2001;4(6):541–6. DOI: 10.1097/00075197-200111000-00014. PMID: 11706291.</mixed-citation></citation-alternatives></ref><ref id="B28"><label>28.</label><citation-alternatives><mixed-citation xml:lang="en">28. Langius J.A., Doornaert P., Spreeuwenberg M.D. et al. Radiotherapy on the neck nodes predicts severe weight loss in patients with early stage laryngeal cancer. Radiother Oncol 2010;97(1):80–5. DOI: 10.1016/j.radonc.2010.02.017. PMID: 20223540.</mixed-citation><mixed-citation xml:lang="ru">Langius J.A., Doornaert P., Spreeuwenberg M.D. et al. Radiotherapy on the neck nodes predicts severe weight loss in patients with early stage laryngeal cancer. Radiother Oncol 2010;97(1):80–5. DOI: 10.1016/j.radonc.2010.02.017. PMID: 20223540.</mixed-citation></citation-alternatives></ref><ref id="B29"><label>29.</label><citation-alternatives><mixed-citation xml:lang="en">29. Matthews T.W., Lampe H.B., Dragosz K. Nutritional status in head and neck cancer patients. J Otolaryngol 1995;24(2):87–91. PMID: 7602677.</mixed-citation><mixed-citation xml:lang="ru">Matthews T.W., Lampe H.B., Dragosz K. Nutritional status in head and neck cancer patients. J Otolaryngol 1995;24(2):87–91. PMID: 7602677.</mixed-citation></citation-alternatives></ref><ref id="B30"><label>30.</label><citation-alternatives><mixed-citation xml:lang="en">30. Unsal D., Mentes B., Akmansu M. et al. Evaluation of nutritional status in cancer patients receiving radiotherapy: a prospective study. Am J Clin Oncol 2006;29(2):183–8. DOI: 10.1097/01.coc.0000198745.94757.ee. PMID: 16601440.</mixed-citation><mixed-citation xml:lang="ru">Unsal D., Mentes B., Akmansu M. et al. Evaluation of nutritional status in cancer patients receiving radiotherapy: a prospective study. Am J Clin Oncol 2006;29(2):183–8. DOI: 10.1097/01.coc.0000198745.94757.ee. PMID: 16601440.</mixed-citation></citation-alternatives></ref><ref id="B31"><label>31.</label><citation-alternatives><mixed-citation xml:lang="en">31. Meyer F., Fortin A., Wang C.S. et al. Predictors of severe acute and late toxicities in patients with localized head-and-neck cancer treated with radiation therapy. Int J Radiat Oncol Biol Phys 2012;82(4):1454–62. DOI: 10.1016/j.ijrobp.2011.04.022. PMID: 21640495.</mixed-citation><mixed-citation xml:lang="ru">Meyer F., Fortin A., Wang C.S. et al. Predictors of severe acute and late toxicities in patients with localized head-and-neck cancer treated with radiation therapy. Int J Radiat Oncol Biol Phys 2012;82(4):1454–62. DOI: 10.1016/j.ijrobp.2011.04.022. PMID: 21640495.</mixed-citation></citation-alternatives></ref><ref id="B32"><label>32.</label><citation-alternatives><mixed-citation xml:lang="en">32. Capuano G., Grosso A., Gentile P.C. et al. Influence of weight loss on outcomes in patients with head and neck cancer undergoing concomitant chemoradiotherapy. Head Neck 2008;30(4):503–8. DOI: 10.1002/hed.20737. PMID: 18098310.</mixed-citation><mixed-citation xml:lang="ru">Capuano G., Grosso A., Gentile P.C. et al. Influence of weight loss on outcomes in patients with head and neck cancer undergoing concomitant chemoradiotherapy. Head Neck 2008;30(4):503–8. DOI: 10.1002/hed.20737. PMID: 18098310.</mixed-citation></citation-alternatives></ref><ref id="B33"><label>33.</label><citation-alternatives><mixed-citation xml:lang="en">33. Langius J.A., van Dijk A.M., Doornaert P. et al. More than 10 % weight loss in head and neck cancer patients during radiotherapy is independently associated with deterioration in quality of life. Nutr Cancer 2013;65(1):76–83. DOI: 10.1080/01635581.2013.741749. PMID: 23368916.</mixed-citation><mixed-citation xml:lang="ru">Langius J.A., van Dijk A.M., Doornaert P. et al. More than 10 % weight loss in head and neck cancer patients during radiotherapy is independently associated with deterioration in quality of life. Nutr Cancer 2013;65(1):76–83. DOI: 10.1080/01635581.2013.741749. PMID: 23368916.</mixed-citation></citation-alternatives></ref><ref id="B34"><label>34.</label><citation-alternatives><mixed-citation xml:lang="en">34. Mourad W.F., Hu K.S., Puckett L. et al. Five-year outcomes of squamous cell carcinoma of the tonsil treated with radiotherapy. Am J Clin Oncol 2014;37:57–62. DOI: 10.1097/COC.0b013e31826b9920. PMID: 23357967.</mixed-citation><mixed-citation xml:lang="ru">Mourad W.F., Hu K.S., Puckett L. et al. Five-year outcomes of squamous cell carcinoma of the tonsil treated with radiotherapy. Am J Clin Oncol 2014;37:57–62. DOI: 10.1097/COC.0b013e31826b9920. PMID: 23357967.</mixed-citation></citation-alternatives></ref><ref id="B35"><label>35.</label><citation-alternatives><mixed-citation xml:lang="en">35. Prevost V., Joubert C., Heutte N., Babin E. Assessment of nutritional status and quality of life in patients treated for head and neck cancer. Eur Ann Otorhinolaryngol Head Neck Dis 2014;131:112–20. DOI: 10.1016/j.anorl.2013.06.007. PMID: 24657191.</mixed-citation><mixed-citation xml:lang="ru">Prevost V., Joubert C., Heutte N., Babin E. Assessment of nutritional status and quality of life in patients treated for head and neck cancer. Eur Ann Otorhinolaryngol Head Neck Dis 2014;131:112–20. DOI: 10.1016/j.anorl.2013.06.007. PMID: 24657191.</mixed-citation></citation-alternatives></ref><ref id="B36"><label>36.</label><citation-alternatives><mixed-citation xml:lang="en">36. Горбунова В.А., Бредер В.В. Качество жизни онкологических больных. Материалы IV ежегодной Российской онкологической конференции, 21–23 ноября 2000 г., Москва. С. 125. Доступно по: http://www.rosoncoweb.ru/library/congress/ru/04/43.php. [Gorbunova V.A., Breder V.V. Quality of life of oncological patients. Proceedings of the IV Annual Russian Oncological Conference, November 21–23, 2000, Moscow. P. 125. Available at: http://www.rosoncoweb.ru/library/congress/ru/04/43.php. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Горбунова В.А., Бредер В.В. Качество жизни онкологических больных. Материалы IV ежегодной Российской онкологической конференции, 21–23 ноября 2000 г., Москва. С. 125. Доступно по: http://www.rosoncoweb.ru/library/congress/ru/04/43.php. [Gorbunova V.A., Breder V.V. Quality of life of oncological patients. Proceedings of the IV Annual Russian Oncological Conference, November 21–23, 2000, Moscow. P. 125. Available at: http://www.rosoncoweb.ru/library/congress/ru/04/43.php. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B37"><label>37.</label><citation-alternatives><mixed-citation xml:lang="en">37. Kumari A.C., Shanmughakumar S., Balasubramaniam P. Assessment of quality of life in head and neck cancer patients with enteral tube feeding. J Cancer Res Therapeutic 2012;8:176.</mixed-citation><mixed-citation xml:lang="ru">Kumari A.C., Shanmughakumar S., Balasubramaniam P. Assessment of quality of life in head and neck cancer patients with enteral tube feeding. J Cancer Res Therapeutic 2012;8:176.</mixed-citation></citation-alternatives></ref><ref id="B38"><label>38.</label><citation-alternatives><mixed-citation xml:lang="en">38. Husaini H., Lazarus C., Hu K. et al. EORTC QOL rating, performance status, and oral outcomes in head-and-neck cancer patients treated with chemoradiation therapy. Int J Radiat Oncol Biol Phys 2013;87:441–2.</mixed-citation><mixed-citation xml:lang="ru">Husaini H., Lazarus C., Hu K. et al. EORTC QOL rating, performance status, and oral outcomes in head-and-neck cancer patients treated with chemoradiation therapy. Int J Radiat Oncol Biol Phys 2013;87:441–2.</mixed-citation></citation-alternatives></ref><ref id="B39"><label>39.</label><citation-alternatives><mixed-citation xml:lang="en">39. Практические рекомендации RUSSCO по нутритивной поддержке онкологических больных, 2016 г. Доступно по: www.rosoncoweb.ru/standarts/RUSSCO/2016/40.pdf. [RUSSCO practical guidelines on nutritional support in oncological patients, 2016. Available at: www.rosoncoweb.ru/standarts/RUSSCO/2016/40.pdf. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Практические рекомендации RUSSCO по нутритивной поддержке онкологических больных, 2016 г. Доступно по: www.rosoncoweb.ru/standarts/RUSSCO/2016/40.pdf. [RUSSCO practical guidelines on nutritional support in oncological patients, 2016. Available at: www.rosoncoweb.ru/standarts/RUSSCO/2016/40.pdf. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B40"><label>40.</label><citation-alternatives><mixed-citation xml:lang="en">40. Обухова О.А., Курмуков И.А., Кашия Ш.Р. Питательная поддержка в онкологии. Онкогинекология 2014;1:34–45. www.osors.com/oncogynecology/JurText/j2014_1/01_14_C34.pdf. [Obukhova O.A., Kurmukov I.A., Kashiya Sh.R. Nutritional support in oncology. Onkoginekologiya = Oncogynecology 2014;1:34–45. Available at: www.osors.com/oncogynecology/JurText/j2014_1/01_14_C34.pdf (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Обухова О.А., Курмуков И.А., Кашия Ш.Р. Питательная поддержка в онкологии. Онкогинекология 2014;1:34–45. www.osors.com/oncogynecology/JurText/j2014_1/01_14_C34.pdf. [Obukhova O.A., Kurmukov I.A., Kashiya Sh.R. Nutritional support in oncology. Onkoginekologiya = Oncogynecology 2014;1:34–45. Available at: www.osors.com/oncogynecology/JurText/j2014_1/01_14_C34.pdf (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B41"><label>41.</label><citation-alternatives><mixed-citation xml:lang="en">41. ESPEN Guidelines for Nutrition Screening 2002 Clin Nutr 2003;22(4):415–21.</mixed-citation><mixed-citation xml:lang="ru">ESPEN Guidelines for Nutrition Screening 2002 Clin Nutr 2003;22(4):415–21.</mixed-citation></citation-alternatives></ref><ref id="B42"><label>42.</label><citation-alternatives><mixed-citation xml:lang="en">42. Duguet A., Bachmann P., Lallemand Y. Summary report of the standards, options and recommendations for malnutrition and nutritional assessment in patients with cancer. Br J Cancer 2003;89(1):92–7. DOI: 10.1038/sj.bjc.6601089. PMID: PMC2753013.</mixed-citation><mixed-citation xml:lang="ru">Duguet A., Bachmann P., Lallemand Y. Summary report of the standards, options and recommendations for malnutrition and nutritional assessment in patients with cancer. Br J Cancer 2003;89(1):92–7. DOI: 10.1038/sj.bjc.6601089. PMID: PMC2753013.</mixed-citation></citation-alternatives></ref><ref id="B43"><label>43.</label><citation-alternatives><mixed-citation xml:lang="en">43. Heys S.D., Schofield A. C., Wahle K.W., Garcia-Caballero M. Nutrition and the surgical patient: triumphs and challenges. Surgeon 2005;3(3):139–44. PMID: 16075997.</mixed-citation><mixed-citation xml:lang="ru">Heys S.D., Schofield A. C., Wahle K.W., Garcia-Caballero M. Nutrition and the surgical patient: triumphs and challenges. Surgeon 2005;3(3):139–44. PMID: 16075997.</mixed-citation></citation-alternatives></ref><ref id="B44"><label>44.</label><citation-alternatives><mixed-citation xml:lang="en">44. Снеговой А.В., Сельчук В.Ю., Салтанов А.И. Нутрикомп АДН Браун Файбер у больных раком желудка с послеоперационными осложнениями. Вестник интенсивной терапии 2003;2:86–7. [Snegovoy A.V., Selchuk V.Yu., Saltanov A.I. Nutricomp ADN Brown Fibre in patients with stomach cancer and postoperative complications. Vestnik intensivnoy terapii = Intensive Care Herald 2003;2:86–7. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Снеговой А.В., Сельчук В.Ю., Салтанов А.И. Нутрикомп АДН Браун Файбер у больных раком желудка с послеоперационными осложнениями. Вестник интенсивной терапии 2003;2:86–7. [Snegovoy A.V., Selchuk V.Yu., Saltanov A.I. Nutricomp ADN Brown Fibre in patients with stomach cancer and postoperative complications. Vestnik intensivnoy terapii = Intensive Care Herald 2003;2:86–7. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B45"><label>45.</label><citation-alternatives><mixed-citation xml:lang="en">45. Снеговой А.В., Лейдерман И.Н., Салтанов А.И., Стрельчук В.Ю. Основные принципы и технологии клинического питания в онкологии: Методическое руководство для врачей. М., 2006. [Snegovoy A.V., Leyderman I.N., Saltanov A.I., Strelchuk V.Yu. Main principles and technologies of clinical nutrition in oncology: Guidelines for doctors. Moscow: 2006. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Снеговой А.В., Лейдерман И.Н., Салтанов А.И., Стрельчук В.Ю. Основные принципы и технологии клинического питания в онкологии: Методическое руководство для врачей. М., 2006. [Snegovoy A.V., Leyderman I.N., Saltanov A.I., Strelchuk V.Yu. Main principles and technologies of clinical nutrition in oncology: Guidelines for doctors. Moscow: 2006. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B46"><label>46.</label><citation-alternatives><mixed-citation xml:lang="en">46. Sánchez Alvarez C., Nuñez Ruiz R., Morán García V. Nutritional support in the patient with GI malignancy. Nutr Hosp 2005;20(2):38–40.</mixed-citation><mixed-citation xml:lang="ru">Sánchez Alvarez C., Nuñez Ruiz R., Morán García V. Nutritional support in the patient with GI malignancy. Nutr Hosp 2005;20(2):38–40.</mixed-citation></citation-alternatives></ref><ref id="B47"><label>47.</label><citation-alternatives><mixed-citation xml:lang="en">47. Луфт В.М., Луфт А.В. Нутриционная поддержка онкологических больных: возможности и противоречия. Вестник интенсивной терапии 2008;2:43–50. [Luft V.M., Luft A.V. Nutritional support of oncological patients: Possibilities and challenges. Vestnik intensivnoy terapii = Intensive Care Herald 2008;2:43–50. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Луфт В.М., Луфт А.В. Нутриционная поддержка онкологических больных: возможности и противоречия. Вестник интенсивной терапии 2008;2:43–50. [Luft V.M., Luft A.V. Nutritional support of oncological patients: Possibilities and challenges. Vestnik intensivnoy terapii = Intensive Care Herald 2008;2:43–50. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B48"><label>48.</label><citation-alternatives><mixed-citation xml:lang="en">48. Лучевая терапия злокачественных опухолей. Рук-во для врачей. Под ред. Е.С. Киселевой. М.: Медицина, 1996. Beam therapy of malignant tumors. Guidelines for doctors. Ed. E.S. Kiselyova. Moscow: Meditsina, 1996. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Лучевая терапия злокачественных опухолей. Рук-во для врачей. Под ред. Е.С. Киселевой. М.: Медицина, 1996. Beam therapy of malignant tumors. Guidelines for doctors. Ed. E.S. Kiselyova. Moscow: Meditsina, 1996. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B49"><label>49.</label><citation-alternatives><mixed-citation xml:lang="en">49. Ярмоненко С.П., Коноплянников А.Г., Вайнсон А.А. Клиническая радиобиология. М.: Медицина, 1992. [Yarmonenko S.P., Konoplyannikov A.G., Vaynson A.A. Clinical radiobiology. Moscow: Meditsina, 1992. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Ярмоненко С.П., Коноплянников А.Г., Вайнсон А.А. Клиническая радиобиология. М.: Медицина, 1992. [Yarmonenko S.P., Konoplyannikov A.G., Vaynson A.A. Clinical radiobiology. Moscow: Meditsina, 1992. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B50"><label>50.</label><citation-alternatives><mixed-citation xml:lang="en">50. Roopashri G., Jayanthi K. Radiotherapy and chemotherapy induced oral mucositis – prevention and current therapeutic modalities. IJDA 2010;2:174–9.</mixed-citation><mixed-citation xml:lang="ru">Roopashri G., Jayanthi K. Radiotherapy and chemotherapy induced oral mucositis – prevention and current therapeutic modalities. IJDA 2010;2:174–9.</mixed-citation></citation-alternatives></ref><ref id="B51"><label>51.</label><citation-alternatives><mixed-citation xml:lang="en">51. Гладилина И.А., Шабанов М.А. Лучевое и химиолучевое лечение распространенного рака ротоглотки. Тверь: Губернская медицина, 2001. [Gladilina I.A., Shabanov M.A. Beam therapy and chemoradiotherapy of advanced oropharyngeal cancer. Tver: Gubernskaya meditsina, 2001. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Гладилина И.А., Шабанов М.А. Лучевое и химиолучевое лечение распространенного рака ротоглотки. Тверь: Губернская медицина, 2001. [Gladilina I.A., Shabanov M.A. Beam therapy and chemoradiotherapy of advanced oropharyngeal cancer. Tver: Gubernskaya meditsina, 2001. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B52"><label>52.</label><citation-alternatives><mixed-citation xml:lang="en">52. Алиева С.Б., Ткачев С.И., Любаев В.Л. и др. Химиолучевая терапия местнораспространенного рака головы и шеи III–IV стадии. Вестник РОНЦ им. Н.Н. Блохина РАМН 2007;18(2): 39–42. [Alieva S.B., Tkachev S.I., Lubaev V.L. et al. Chemoradiotherapy of stage III–IV locally advanced head and neck cancer. Vestnik RONC im. Blokhina = Journal of N.N. Blokhin Russian Cancer Research Center RAMS 2007;18(2):39–42. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Алиева С.Б., Ткачев С.И., Любаев В.Л. и др. Химиолучевая терапия местнораспространенного рака головы и шеи III–IV стадии. Вестник РОНЦ им. Н.Н. Блохина РАМН 2007;18(2): 39–42. [Alieva S.B., Tkachev S.I., Lubaev V.L. et al. Chemoradiotherapy of stage III–IV locally advanced head and neck cancer. Vestnik RONC im. Blokhina = Journal of N.N. Blokhin Russian Cancer Research Center RAMS 2007;18(2):39–42. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B53"><label>53.</label><citation-alternatives><mixed-citation xml:lang="en">53. Сопроводительная терапия в онкологии. Практическое руководство. Под ред. С.Ю. Мооркрафта, Д.Л.Ю. Ли, Д. Каннингэма; пер. с англ.; Под ред. А.Д. Каприна. М.: Гэотар, 2016. [Clinical problems in oncology: A practical guide to management. Eds. S.Y. Moorkraft, D.L.Y. Lee, D.D. Cunningham; Translation from English. Ed. A.D. Kaprin. Moscow: Geotar, 2016. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Сопроводительная терапия в онкологии. Практическое руководство. Под ред. С.Ю. Мооркрафта, Д.Л.Ю. Ли, Д. Каннингэма; пер. с англ.; Под ред. А.Д. Каприна. М.: Гэотар, 2016. [Clinical problems in oncology: A practical guide to management. Eds. S.Y. Moorkraft, D.L.Y. Lee, D.D. Cunningham; Translation from English. Ed. A.D. Kaprin. Moscow: Geotar, 2016. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B54"><label>54.</label><citation-alternatives><mixed-citation xml:lang="en">54. Brady O., Donnelly M., Horgan A., Maher M. Post-radiotherapy side effects for head and neck cancer – the patient’s perspective. Proceedings of the Nutrition Society. Harrogate; p. E283.</mixed-citation><mixed-citation xml:lang="ru">Brady O., Donnelly M., Horgan A., Maher M. Post-radiotherapy side effects for head and neck cancer – the patient’s perspective. Proceedings of the Nutrition Society. Harrogate; p. E283.</mixed-citation></citation-alternatives></ref><ref id="B55"><label>55.</label><citation-alternatives><mixed-citation xml:lang="en">55. Galloway T., Amdur R. Management and prevention of complications during initial treatment of head and neck cancer. In: Posner M., Brockstein B., Brizel D., Deschler D. (eds). UpToDate, Waltham, MA, 2014.</mixed-citation><mixed-citation xml:lang="ru">Galloway T., Amdur R. Management and prevention of complications during initial treatment of head and neck cancer. In: Posner M., Brockstein B., Brizel D., Deschler D. (eds). UpToDate, Waltham, MA, 2014.</mixed-citation></citation-alternatives></ref><ref id="B56"><label>56.</label><citation-alternatives><mixed-citation xml:lang="en">56. Langius J.A., Zandbergen M.C., Van Tulder M.W. et al. Effect of nutritional interventions on nutritional status of patients with head and neck cancer receiving (chemo)radiotherapy: A systematic review. Clin Nutr 2013;32:671–8. DOI: 10.1016/j.clnu.2013.06.012. PMID: 23845384.</mixed-citation><mixed-citation xml:lang="ru">Langius J.A., Zandbergen M.C., Van Tulder M.W. et al. Effect of nutritional interventions on nutritional status of patients with head and neck cancer receiving (chemo)radiotherapy: A systematic review. Clin Nutr 2013;32:671–8. DOI: 10.1016/j.clnu.2013.06.012. PMID: 23845384.</mixed-citation></citation-alternatives></ref><ref id="B57"><label>57.</label><citation-alternatives><mixed-citation xml:lang="en">57. Payakachat N., Ounpraseuth S., Suen J.Y. Late complications and long-term quality of life for survivors (&gt;5 years) with history of head and neck cancer. Head Neck 2013;35:819–25. DOI: 10.1002/hed.23035. PMID: 22807083.</mixed-citation><mixed-citation xml:lang="ru">Payakachat N., Ounpraseuth S., Suen J.Y. Late complications and long-term quality of life for survivors (&gt;5 years) with history of head and neck cancer. Head Neck 2013;35:819–25. DOI: 10.1002/hed.23035. PMID: 22807083.</mixed-citation></citation-alternatives></ref><ref id="B58"><label>58.</label><citation-alternatives><mixed-citation xml:lang="en">58. Paleri V., Roe J.W.G., Strojan P. et al. Strategies to reduce long-term postchemoradiation dysphagia in patients with head and neck cancer: An evidence-based review: Strategies to reduce dysphagia after chemoradiation. Head Neck 2014;36: 431–43. DOI: 10.1002/hed.23251. PMID: 23828486.</mixed-citation><mixed-citation xml:lang="ru">Paleri V., Roe J.W.G., Strojan P. et al. Strategies to reduce long-term postchemoradiation dysphagia in patients with head and neck cancer: An evidence-based review: Strategies to reduce dysphagia after chemoradiation. Head Neck 2014;36: 431–43. DOI: 10.1002/hed.23251. PMID: 23828486.</mixed-citation></citation-alternatives></ref><ref id="B59"><label>59.</label><citation-alternatives><mixed-citation xml:lang="en">59. Wendt T.G., Grabenbauer G.G., Rodel C.M. et al. Simultaneous radiochemotherapy versus radiotherapy alone in advanced head and neck cancer: A randomized multicenter study. J Clin Oncol 1998;16:1318– 24. DOI: 10.1200/JCO.1998.16.4.1318. PMID: 9552032.</mixed-citation><mixed-citation xml:lang="ru">Wendt T.G., Grabenbauer G.G., Rodel C.M. et al. Simultaneous radiochemotherapy versus radiotherapy alone in advanced head and neck cancer: A randomized multicenter study. J Clin Oncol 1998;16:1318– 24. DOI: 10.1200/JCO.1998.16.4.1318. PMID: 9552032.</mixed-citation></citation-alternatives></ref><ref id="B60"><label>60.</label><citation-alternatives><mixed-citation xml:lang="en">60. Практические рекомендации по лекарственному лечению злокачественных опухолей (RUSSCO). Под ред. В.М. Моисеенко. М.: Изд-е Российского общества клинической онкологии, 2015.Доступно по: http://www.rosoncoweb.ru/standarts/RUSSCO/2014/. [Practical guidelines on drug therapy of malignant tumors (RUSSCO). Ed. V.M. Moiseenko. Moscow: Izdanie Rossiyskogo Obshchestva klinicheskoy onkologii, 2015. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Практические рекомендации по лекарственному лечению злокачественных опухолей (RUSSCO). Под ред. В.М. Моисеенко. М.: Изд-е Российского общества клинической онкологии, 2015.Доступно по: http://www.rosoncoweb.ru/standarts/RUSSCO/2014/. [Practical guidelines on drug therapy of malignant tumors (RUSSCO). Ed. V.M. Moiseenko. Moscow: Izdanie Rossiyskogo Obshchestva klinicheskoy onkologii, 2015. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B61"><label>61.</label><citation-alternatives><mixed-citation xml:lang="en">61. Bonner J.A., Harari P.M., Giralt J. et al. Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab- induced rash and survival. Lancet Oncol 2010;11:21–8. DOI: 10.1016/S1470-2045(09)70311-0. PMID: 19897418.</mixed-citation><mixed-citation xml:lang="ru">Bonner J.A., Harari P.M., Giralt J. et al. Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab- induced rash and survival. Lancet Oncol 2010;11:21–8. DOI: 10.1016/S1470-2045(09)70311-0. PMID: 19897418.</mixed-citation></citation-alternatives></ref><ref id="B62"><label>62.</label><citation-alternatives><mixed-citation xml:lang="en">62. Curran D., Giralt J., Harari P.M. et al. Quality of life in head and neck cancer patients after treatment with high-dose radiotherapy alone or in combination with cetuximab. J Clin Oncol 2007;25:2191–7. DOI: 10.1200/JCO.2006.08.8005. PMID: 17538164.</mixed-citation><mixed-citation xml:lang="ru">Curran D., Giralt J., Harari P.M. et al. Quality of life in head and neck cancer patients after treatment with high-dose radiotherapy alone or in combination with cetuximab. J Clin Oncol 2007;25:2191–7. DOI: 10.1200/JCO.2006.08.8005. PMID: 17538164.</mixed-citation></citation-alternatives></ref><ref id="B63"><label>63.</label><citation-alternatives><mixed-citation xml:lang="en">63. Bozzetti F., Bozzetti V. Efficacy of enteral and parenteral nutrition in cancer patients. Nestle Nutr Workshop Ser Clin Perform Programme 2005;10:127–39. DOI: 10.1159/000083302. PMID: 15818026.</mixed-citation><mixed-citation xml:lang="ru">Bozzetti F., Bozzetti V. Efficacy of enteral and parenteral nutrition in cancer patients. Nestle Nutr Workshop Ser Clin Perform Programme 2005;10:127–39. DOI: 10.1159/000083302. PMID: 15818026.</mixed-citation></citation-alternatives></ref><ref id="B64"><label>64.</label><citation-alternatives><mixed-citation xml:lang="en">64. Снеговой А.В., Салтанов А.И., Манзюк Л.В. и др. Оценка эффективности нутритивной поддержки энтеральной смесью «Фортикер» у пациентов с онкологическими заболеваниями в период лучевой и химиотерапии. Вестник интенсивной терапии 2009;(4):77–83. [Snegovoy A.V., Saltanov A.I., Manzuk L.V. et al. Evaluation of effectiveness of Forticare enteral mixture in patients with oncological diseases during beam therapy and chemoradiotherapy. Vestnik intensivnoy terapii = Intensive Care Herald 2009;(4):77–83. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Снеговой А.В., Салтанов А.И., Манзюк Л.В. и др. Оценка эффективности нутритивной поддержки энтеральной смесью «Фортикер» у пациентов с онкологическими заболеваниями в период лучевой и химиотерапии. Вестник интенсивной терапии 2009;(4):77–83. [Snegovoy A.V., Saltanov A.I., Manzuk L.V. et al. Evaluation of effectiveness of Forticare enteral mixture in patients with oncological diseases during beam therapy and chemoradiotherapy. Vestnik intensivnoy terapii = Intensive Care Herald 2009;(4):77–83. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B65"><label>65.</label><citation-alternatives><mixed-citation xml:lang="en">65. Решетов И.В., Егоров Г.Н. Предоперационная нутритивная терапия пациентов с опухолями головы и шеи. Голова и шея 2013;2:27–34. [Reshetov I.V., Egorov G.N. Preoperative nutritional therapy in patients with head and neck tumors. Golova i sheya = Head and Neck 2013;(2):27–34. (In Russ.)].</mixed-citation><mixed-citation xml:lang="ru">Решетов И.В., Егоров Г.Н. Предоперационная нутритивная терапия пациентов с опухолями головы и шеи. Голова и шея 2013;2:27–34. [Reshetov I.V., Egorov G.N. Preoperative nutritional therapy in patients with head and neck tumors. Golova i sheya = Head and Neck 2013;(2):27–34. (In Russ.)].</mixed-citation></citation-alternatives></ref><ref id="B66"><label>66.</label><citation-alternatives><mixed-citation xml:lang="en">66. Elia M., Van Bokhorst-de van der Schueren M.A., Garvey J. et al. Enteral (oral or tube administration) nutritional support and eicosapentaenoic acid in patients with cancer: a systematic review. Int J Oncol 2006;28(1):5–23. PMID: 16327975.</mixed-citation><mixed-citation xml:lang="ru">Elia M., Van Bokhorst-de van der Schueren M.A., Garvey J. et al. Enteral (oral or tube administration) nutritional support and eicosapentaenoic acid in patients with cancer: a systematic review. Int J Oncol 2006;28(1):5–23. PMID: 16327975.</mixed-citation></citation-alternatives></ref><ref id="B67"><label>67.</label><citation-alternatives><mixed-citation xml:lang="en">67. Pauloski B.R. Rehabilitation of dysphagia following head and neck cancer. Phys Med Rehabil Clin N Am 2008;9:889–928. DOI: 10.1016/j.pmr.2008.05.010. PMID: 18940647.</mixed-citation><mixed-citation xml:lang="ru">Pauloski B.R. Rehabilitation of dysphagia following head and neck cancer. Phys Med Rehabil Clin N Am 2008;9:889–928. DOI: 10.1016/j.pmr.2008.05.010. PMID: 18940647.</mixed-citation></citation-alternatives></ref></ref-list></back></article>
