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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">244</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2016-6-4-11-14</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DIAGNOSIS AND TREATMENT OF HEAD AND NECK TUMORS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ ГОЛОВЫ И ШЕИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">ANALYSIS RESULTS OF COMBINED TREATMENT OF PATIENTS WITH VERIFIED CANCER OF THE CERVICAL ESOPHAGUS AND HYPOPHARYNX WITH THE APPLICATION OF SURGICAL TREATMENT WITH ONE-STAGE DEFECT’S PLASTIC</article-title><trans-title-group xml:lang="ru"><trans-title>АНАЛИЗ РЕЗУЛЬТАТОВ КОМБИНИРОВАННОГО ЛЕЧЕНИЯ ПАЦИЕНТОВ С ВЕРИФИЦИРОВАННЫМ РАКОМ ШЕЙНОГО ОТДЕЛА ПИЩЕВОДА И ГОРТАНОГЛОТКИ С ПРИМЕНЕНИЕМ ХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ С ОДНОМОМЕНТНОЙ ПЛАСТИКОЙ ДЕФЕКТА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Radzhabova</surname><given-names>Z. A.</given-names></name><name xml:lang="ru"><surname>Раджабова</surname><given-names>З. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Замира Ахмед-Гаджиевна Раджабова - Хирургическое отделение опухолей головы и шеи.</p><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68, <ext-link ext-link-type="uri" xlink:href="mailto:radzam@mail.ru">radzam@mail.ru</ext-link></p></bio><email>radzam@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Levchenko</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Левченко</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Хирургическое отделение опухолей головы и шеи.197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Dunaevskiy</surname><given-names>I. V.</given-names></name><name xml:lang="ru"><surname>Дунаевский</surname><given-names>И. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Хирургическое отделение опухолей головы и шеи.197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gorokhov</surname><given-names>L. V.</given-names></name><name xml:lang="ru"><surname>Горохов</surname><given-names>Л. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Хирургическое отделение опухолей головы и шеи.197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kotov</surname><given-names>M. A.</given-names></name><name xml:lang="ru"><surname>Котов</surname><given-names>М. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Хирургическое отделение опухолей головы и шеи.</p><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Khandogin</surname><given-names>N. V.</given-names></name><name xml:lang="ru"><surname>Хандогин</surname><given-names>Н. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Хирургическое отделение опухолей головы и шеи.197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Rakitina</surname><given-names>D. А.</given-names></name><name xml:lang="ru"><surname>Ракитина</surname><given-names>Д. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Хирургическое отделение опухолей головы и шеи.197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nazhmudinov</surname><given-names>R. А.</given-names></name><name xml:lang="ru"><surname>Нажмудинов</surname><given-names>Р. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Хирургическое отделение опухолей головы и шеи.197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Girshovich</surname><given-names>M. M.</given-names></name><name xml:lang="ru"><surname>Гиршович</surname><given-names>М. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Хирургическое отделение опухолей головы и шеи.</p><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tyuryaeva</surname><given-names>E. I.</given-names></name><name xml:lang="ru"><surname>Тюряева</surname><given-names>Е. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Хирургическое отделение опухолей головы и шеи.197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Tkachenko</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Ткаченко</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Хирургическое отделение опухолей головы и шеи.</p><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Ponomareva</surname><given-names>О. I.</given-names></name><name xml:lang="ru"><surname>Пономарева</surname><given-names>О. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyy Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Хирургическое отделение опухолей головы и шеи.197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Petrov Research Institute of Oncology</institution></aff><aff><institution xml:lang="ru">Научно-исследовательский институт онкологии имени Н.Н. Петрова</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2016-12-08" publication-format="electronic"><day>08</day><month>12</month><year>2016</year></pub-date><volume>6</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>11</fpage><lpage>14</lpage><history><date date-type="received" iso-8601-date="2017-04-08"><day>08</day><month>04</month><year>2017</year></date><date date-type="accepted" iso-8601-date="2017-04-08"><day>08</day><month>04</month><year>2017</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2016, Radzhabova Z.A., Levchenko E.V., Dunaevskiy I.V., Gorokhov L.V., Kotov M.A., Khandogin N.V., Rakitina D.А., Nazhmudinov R.А., Girshovich M.M., Tyuryaeva E.I., Tkachenko E.V., Ponomareva О.I.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2016, Раджабова З.А., Левченко Е.В., Дунаевский И.В., Горохов Л.В., Котов М.А., Хандогин Н.В., Ракитина Д.А., Нажмудинов Р.А., Гиршович М.М., Тюряева Е.И., Ткаченко Е.В., Пономарева О.И.</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="en">Radzhabova Z.A., Levchenko E.V., Dunaevskiy I.V., Gorokhov L.V., Kotov M.A., Khandogin N.V., Rakitina D.А., Nazhmudinov R.А., Girshovich M.M., Tyuryaeva E.I., Tkachenko E.V., Ponomareva О.I.</copyright-holder><copyright-holder xml:lang="ru">Раджабова З.А., Левченко Е.В., Дунаевский И.В., Горохов Л.В., Котов М.А., Хандогин Н.В., Ракитина Д.А., Нажмудинов Р.А., Гиршович М.М., Тюряева Е.И., Ткаченко Е.В., Пономарева О.И.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/244">https://ogsh.abvpress.ru/jour/article/view/244</self-uri><abstract xml:lang="en"><p>In the treatment of many unresolved issues, indicating the need for research aimed at finding more effective treatment approaches. The aim of the study is to analyze the results of combined treatment of patients with widespread forms of cancer of the cervical esophagus and hypopharynx with the application of surgical treatment in the amount of pharyngolaryngitis with single-step plastic of the defect. A retrospective analysis of results of combined treatment of 28 patients with a verified diagnosis of cancer of the cervical esophagus and hypopharynx. Combined treatment of patients with cancer of the cervical esophagus and hypopharynx included the following treatments: induction chemoradiotherapy according to the scheme cisplatin/5-fluorouracil, external beam radiation therapy 65 Gy, brachytherapy (7 Gy 1 time per week, 3 sessions), surgical treatment with one-stage plastic of the esophagus. In 7 patients (25 %) was achieved complete regression on the background of induction chemotherapy, 21 patients (75 %) received the treatment in full. Postoperative mortality rate was of 9.52 %, post-operative complications such as anastomosis dehiscence – 19 %.</p></abstract><trans-abstract xml:lang="ru"><p/></trans-abstract><kwd-group xml:lang="en"><kwd>cancer of the cervical esophagus</kwd><kwd>cancer of the hypopharynx</kwd><kwd>laryngopharyngectomy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак шейного отдела пищевода</kwd><kwd>рак гортаноглотки</kwd><kwd>ларингофарингэзофагэктомия</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Чиссов В.И., Старинский В.В., Петрова Г.В., Злокачественные новообразования в России в 2008 году (заболеваемость и смертность). М., 2010. 256 с. [Chissov V.I., Starinskiy V.V., Petrova G.V. Malignant neoplasms in Russia in 2008 (morbidity and mortality). Moscow, 2010. 256 p. 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