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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">259</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2017-7-2-12-15</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DIAGNOSIS AND TREATMENT OF HEAD AND NECK TUMORS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ ГОЛОВЫ И ШЕИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">THE SIGNIFICANCE OF THE METHOD OF ULTRASONIC RESEARCH OF A THYROID GLAND WITH CONTRAST ENHANCEMENT IN THE DIFFERENTIAL DIAGNOSIS OF FOCAL NODULAR FORMATIONS</article-title><trans-title-group xml:lang="ru"><trans-title>ЗНАЧИМОСТЬ МЕТОДА УЛЬТРАЗВУКОВОГО ИССЛЕДОВАНИЯ ЩИТОВИДНОЙ ЖЕЛЕЗЫ С КОНТРАСТНЫМ УСИЛЕНИЕМ В ДИФФЕРЕНЦИАЛЬНОЙ ДИАГНОСТИКЕ ОЧАГОВЫХ УЗЛОВЫХ ОБРАЗОВАНИЙ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Rakitina</surname><given-names>D. A.</given-names></name><name xml:lang="ru"><surname>Ракитина</surname><given-names>Д. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyi Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Хирургическое отделение опухолей головы и шеи.</p><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Belyaev</surname><given-names>A. M.</given-names></name><name xml:lang="ru"><surname>Беляев</surname><given-names>А. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyi Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Хирургическое отделение опухолей головы и шеи.</p><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Radzhabova</surname><given-names>Z. A.</given-names></name><name xml:lang="ru"><surname>Раджабова</surname><given-names>З. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyi Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Замира Ахмед-Гаджиевна Раджабова - Хирургическое отделение опухолей головы и шеи.</p><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><email>radzam@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kostromina</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Костромина</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyi Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Хирургическое отделение опухолей головы и шеи.</p><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kotov</surname><given-names>M. A.</given-names></name><name xml:lang="ru"><surname>Котов</surname><given-names>М. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyi Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Хирургическое отделение опухолей головы и шеи.</p><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nazhmudinov</surname><given-names>R. A.</given-names></name><name xml:lang="ru"><surname>Нажмудинов</surname><given-names>Р. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Surgical Department of Head and Neck Tumors.</p><p>68 Leningradskaya St., Pesochnyi Settlement, Saint Petersburg 197758</p></bio><bio xml:lang="ru"><p>Хирургическое отделение опухолей головы и шеи.</p><p>197758 Санкт-Петербург, пос. Песочный, ул. Ленинградская, 68</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Petrov Research Institute of Oncology at the Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «НИИ онкологии им. Н.Н. Петрова» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2017-06-26" publication-format="electronic"><day>26</day><month>06</month><year>2017</year></pub-date><volume>7</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>12</fpage><lpage>15</lpage><history><date date-type="received" iso-8601-date="2017-06-26"><day>26</day><month>06</month><year>2017</year></date><date date-type="accepted" iso-8601-date="2017-06-26"><day>26</day><month>06</month><year>2017</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2017, Rakitina D.A., Belyaev A.M., Radzhabova Z.A., Kostromina E.V., Kotov M.A., Nazhmudinov R.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2017, Ракитина Д.А., Беляев А.М., Раджабова З.А., Костромина Е.В., Котов М.А., Нажмудинов Р.А.</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="en">Rakitina D.A., Belyaev A.M., Radzhabova Z.A., Kostromina E.V., Kotov M.A., Nazhmudinov R.A.</copyright-holder><copyright-holder xml:lang="ru">Ракитина Д.А., Беляев А.М., Раджабова З.А., Костромина Е.В., Котов М.А., Нажмудинов Р.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/259">https://ogsh.abvpress.ru/jour/article/view/259</self-uri><abstract xml:lang="en"><p><bold>Introduction</bold>. Currently thyroid nodules are a widespread problem in clinical oncology and head and neck cancer, malignant focal lesions constitute more than 15–20  %. Accurate diagnosis is very important and determines treatment, as well as the volume of surgical intervention.</p><p><bold>Objective </bold>– determination of the diagnostic value of the method of contrast-enhanced ultrasound in the diagnosis of thyroid cancer. Reference materials were the results of the histological study of surgical specimens.</p><p><bold>Method.</bold> Performed a retrospective analysis of medical records of 42 patients who underwent surgery at the surgical department of head and neck tumors on the verified thyroid cancer in the N.N. Petrov Research Institute of Oncology at the Ministry of Health of Russia. The number of female patients was 36 persons (85.5 %), the number of men was 6 people (14.5 %). The average age of patients among men was 55.5 years, women – 46 years. All patients underwent surgical treatment in the amount of extirpation of the thyroid gland – 16 patients (37.5 %), hemithyroidectomy – 26 patients (62.5 %).</p><p><bold>Results.</bold> The sensitivity of ultrasound with contrast in the diagnosis of cancer of the thyroid gland was 94.11 %, specificity was 87.5 %, diagnostic accuracy – 92.8 %.</p><p><bold>Conclusions.</bold> The technique of ultrasound nodules thyroid with intravenous contrast enhancement has an excellent diagnostic properties, allowing to identify and verify thyroid cancer is 8 % more accurately in comparison with standard ultrasound technique.</p></abstract><trans-abstract xml:lang="ru"><p/></trans-abstract><kwd-group xml:lang="en"><kwd>thyroid cancer</kwd><kwd>ultrasonography</kwd><kwd>contrast enhancement</kwd><kwd>thyroid nodules</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак щитовидной железы</kwd><kwd>ультразвуковая диагностика</kwd><kwd>контрастное усиление</kwd><kwd>узлы щитовидной железы</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. 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