Head and Neck TumorsHead and Neck TumorsОпухоли головы и шеи2222-14682411-4634Publishing House ABV Press29510.17650/2222-1468-2017-7-3-103-107CLINICAL CASEКЛИНИЧЕСКИЙ СЛУЧАЙ18F-FLUORODEOXYGLUCOSE POSITRON EMISSION TOMOGRAPHY COMBINED WITH COMPUTED TOMOGRAPHY IN EVALUATION OF EFFECTIVENESS OF TARGETED THERAPY OF RADIOACTIVE IODINE-REFRACTORY DIFFERENTIATED THYROID CANCER (CLINICAL OBSERVATION)СОВМЕЩЕННАЯ ПОЗИТРОННО-ЭМИССИОННАЯ И КОМПЬЮТЕРНАЯ ТОМОГРАФИЯ С 18F-ФТОРДЕЗОКСИГЛЮКОЗОЙ В ОЦЕНКЕ ЭФФЕКТИВНОСТИ ТАРГЕТНОЙ ТЕРАПИИ ПРИ РАДИОЙОДРЕЗИСТЕНТНОМ ВЫСОКОДИФФЕРЕНЦИРОВАННОМ РАКЕ ЩИТОВИДНОЙ ЖЕЛЕЗЫ (КЛИНИЧЕСКОЕ НАБЛЮДЕНИЕ)OdzharovaA. A.ОджароваА. А.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478.

Акгуль Атаевна Оджарова.

115478 Москва, Каширское шоссе, 24. 

 

odzharova07@yandex.ruDolgushinM. B.ДолгушинМ. Б.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478.

115478 Москва, Каширское шоссе, 24. 

 

MudunovA. M.МудуновА. М.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478.

115478 Москва, Каширское шоссе, 24.

RomanovI. S.РомановИ. С.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478.

115478 Москва, Каширское шоссе, 24.

TulinR. E.ТулинП. Е.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478.

115478 Москва, Каширское шоссе, 24.

NevzorovD. I.НевзоровД. И.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478.

115478 Москва, Каширское шоссе, 24.

N.N. Blokhin National Medical Research Oncology Center, Ministry of Health of Russia.ФГБУ «НМИЦ онкологии им. Н.Н. Блохина» Минздрава России.07112017731031070811201708112017Copyright ©; 2017, Odzharova A.A., Dolgushin M.B., Mudunov A.M., Romanov I.S., Tulin R.E., Nevzorov D.I.Copyright ©; 2017, Оджарова А.А., Долгушин М.Б., Мудунов А.М., Романов И.С., Тулин П.Е., Невзоров Д.И.2017Odzharova A.A., Dolgushin M.B., Mudunov A.M., Romanov I.S., Tulin R.E., Nevzorov D.I.Оджарова А.А., Долгушин М.Б., Мудунов А.М., Романов И.С., Тулин П.Е., Невзоров Д.И.https://creativecommons.org/licenses/by/4.0https://ogsh.abvpress.ru/jour/article/view/295

N.N. Blokhin National Medical Research Oncology Center, Ministry of Health of Russia; 24 Kashirskoe Shosse, Moscow 115478, Russia Positron emission tomography (PET) with 18F-fluorodeoxyglucose is included in the algorithm of examination and monitoring in patients with radioactive iodine-refractory differentiated thyroid cancer. In assessing the effectiveness of targeted therapy, criteria based on the values of SUVmax (standardized uptake value) in metastases are used. The article shows the results of PET studies in a patient with radioactive iodine-refractory papillary thyroid cancer treated with sorafenib. The dynamics of tumor activity of metastases by different quantitative indicators were evaluated.

Позитронная эмиссионная томография (ПЭТ) с 18F-фтордезоксиглюкозой включена в алгоритм обследования и наблюдения у больных высокодифференцированным раком щитовидной железы с уже установленной радиойодрезистентностью или при подозрении на нее. При оценке эффективности таргетной терапии используются критерии, основанные на значениях SUVmax (стандартизованный уровень накопления) в метастазах. В статье показаны результаты ПЭТ-исследований у больной радиойодрезистентным папиллярным раком щитовидной железы, получавшей лечение препаратом сорафениб. Оценена динамика опухолевой активности метастазов по разным количественным показателям.

differentiated thyroid cancerpositron emission tomography/computed tomographymetabolic tumor volume and total lesion glycolysissorafenibвысокодифференцированный рак щитовидной железыпозитронная эмиссионная томография/компьютерная томографияметаболический объем и общий гликолиз опухолисорафениб1. Злокачественные новообразования в России в 2015 году (заболеваемость и смертность). Под ред. А.Д. Каприна, В.В. Старинского, Г .В. Петровой. М.: МНИОИ им. П.А. Герцена – филиал ФГБУ «НМИРЦ» Минздрава России, 2017. Доступно по: http://oncologyassociation.ru/docs/medstat/sostoyznie/2015.pdf. [State of oncological care in Russia in 2015 (morbidity and mortality). Editors: A.D. Kaprin, V.V. Starinskiy, G.V. Petrova. Moscow: MNIOI imeni P.A. Hertzena – filial FGBU “NMIRC” Minzdrava Rossii, 2017. (In Russ.) Available at: http://oncology-association.ru/docs/medstat/ sostoyznie/2015.pdf.].Злокачественные новообразования в России в 2015 году (заболеваемость и смертность). Под ред. А.Д. Каприна, В.В. 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