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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">37</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2013-0-1-33-38</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОРНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">PROGNOSTIC CRITERIA FOR THE COURSE OF SQUAMOUS CELL CARCINOMA OF THE LARYNX (A REVIEW OF LITERATURE)</article-title><trans-title-group xml:lang="ru"><trans-title>ПРОГНОСТИЧЕСКИЕ КРИТЕРИИ ТЕЧЕНИЯ ПЛОСКОКЛЕТОЧНОГО РАКА ГОРТАНИ (ОБЗОР ЛИТЕРАТУРЫ)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gorban</surname><given-names>N. A.</given-names></name><name xml:lang="ru"><surname>Горбань</surname><given-names>Н. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Popuchiev</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Попучиев</surname><given-names>В. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Baryshev</surname><given-names>V. V.</given-names></name><name xml:lang="ru"><surname>Барышев</surname><given-names>В. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>baryshev@mrrc.obninsk.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Medical Radiology Research Center, Ministry of Health of Russia, Obninsk</institution></aff><aff><institution xml:lang="ru">ФГБУ «Медицинский радиологический научный центр» Минздрава России, Обнинск</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2013</year></pub-date><volume>3</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>33</fpage><lpage>38</lpage><history><date date-type="received" iso-8601-date="2015-04-16"><day>16</day><month>04</month><year>2015</year></date><date date-type="accepted" iso-8601-date="2015-04-16"><day>16</day><month>04</month><year>2015</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, Gorban N.A., Popuchiev V.V., Baryshev V.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, Горбань Н.А., Попучиев В.В., Барышев В.В.</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">Gorban N.A., Popuchiev V.V., Baryshev V.V.</copyright-holder><copyright-holder xml:lang="ru">Горбань Н.А., Попучиев В.В., Барышев В.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/37">https://ogsh.abvpress.ru/jour/article/view/37</self-uri><abstract xml:lang="en"><p>The review evaluates the use of the most common molecular biological markers to predict the course of squamous cell carcinoma of the larynx. It is proposed to use the markers Ki-67 and p53 as criteria and to take into account the specific features of the angioarchitectonics of a tumor.</p></abstract><trans-abstract xml:lang="ru"><p>В обзоре дана оценка использования наиболее распространенных молекулярно-биологических маркеров для прогноза течения плоскоклеточного рака гортани. В качестве критериев предлагается использовать маркеры Ki-67 и р53, а также учитывать особенности ангиоархитектоники опухоли.</p></trans-abstract><kwd-group xml:lang="en"><kwd>squamous cell carcinoma of the larynx</kwd><kwd>prognosis</kwd><kwd>Ki-67</kwd><kwd>p53</kwd><kwd>angioarchitectonics</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>плоскоклеточный рак гортани</kwd><kwd>прогноз</kwd><kwd>Кi-67</kwd><kwd>р53</kwd><kwd>ангиоархитектоника</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Acikalin M.F., Oner U., Tel N. et al. 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