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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">376</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2018-8-4-61-67</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Ameloblastic carcinoma of lower jaw (case report)</article-title><trans-title-group xml:lang="ru"><trans-title>Амелобластическая карцинома нижней челюсти (клинический случай)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Davudov</surname><given-names>M. M.</given-names></name><name xml:lang="ru"><surname>Давудов</surname><given-names>М. М.</given-names></name></name-alternatives><address><country country="AZ">Azerbaijan</country></address><bio xml:lang="en"><p>23 Bakikhanov St., Baku AZ 1022</p></bio><bio xml:lang="ru"><p>Магомед Мирабдуллаевич Давудов.</p><p>AZ1022 Баку, ул. Бакиханова, 23</p></bio><email>mahammad_davud@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Rahimov</surname><given-names>Ch. R.</given-names></name><name xml:lang="ru"><surname>Рагимов</surname><given-names>Ч. Р.</given-names></name></name-alternatives><address><country country="AZ">Azerbaijan</country></address><bio xml:lang="en"><p>23 Bakikhanov St., Baku AZ 1022</p></bio><bio xml:lang="ru"><p>AZ1022 Баку, ул. Бакиханова, 23</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9543-990X</contrib-id><name-alternatives><name xml:lang="en"><surname>Akhundov</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Ахундов</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow 115478</p></bio><bio xml:lang="ru"><p>115478 Москва, Каширское шоссе, 24</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Alikuliev</surname><given-names>V. K.</given-names></name><name xml:lang="ru"><surname>Аликулиев</surname><given-names>В. К.</given-names></name></name-alternatives><address><country country="AZ">Azerbaijan</country></address><bio xml:lang="en"><p>23 Bakikhanov St., Baku AZ 1022</p></bio><bio xml:lang="ru"><p>AZ1022 Баку, ул. Бакиханова, 23</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2793-5597</contrib-id><name-alternatives><name xml:lang="en"><surname>Safarov</surname><given-names>D. A.</given-names></name><name xml:lang="ru"><surname>Сафаров</surname><given-names>Д. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>24 Kashirskoe Shosse, Moscow 115478</p></bio><bio xml:lang="ru"><p>115478 Москва, Каширское шоссе, 24</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Osmanov</surname><given-names>Sh. Sh.</given-names></name><name xml:lang="ru"><surname>Османов</surname><given-names>Ш. Ш.</given-names></name></name-alternatives><address><country country="AZ">Azerbaijan</country></address><bio xml:lang="en"><p>18 Chamanzeminli St., Baku AZ 1078</p></bio><bio xml:lang="ru"><p>AZ1078 Баку, ул. Чеменземинли, 18</p></bio><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Dobrokhotova</surname><given-names>V. Z.</given-names></name><name xml:lang="ru"><surname>Доброхотова</surname><given-names>В. З.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Build. 4, 2 Bol’shaya Pitogovskaya St., Moscow 119991</p></bio><bio xml:lang="ru"><p>119991 Москва, ул. Большая Пироговская, 2, стр. 4</p></bio><xref ref-type="aff" rid="aff4"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Azerbaijan Medical University</institution></aff><aff><institution xml:lang="ru">Азербайджанский медицинский университет</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Baku City Hospital</institution></aff><aff><institution xml:lang="ru">Частная клиника Baku City Hospital</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2018-12-13" publication-format="electronic"><day>13</day><month>12</month><year>2018</year></pub-date><volume>8</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>61</fpage><lpage>67</lpage><history><date date-type="received" iso-8601-date="2019-01-13"><day>13</day><month>01</month><year>2019</year></date><date date-type="accepted" iso-8601-date="2019-01-13"><day>13</day><month>01</month><year>2019</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2018, Davudov M.M., Rahimov C.R., Akhundov A.A., Alikuliev V.K., Safarov D.A., Osmanov S.S., Dobrokhotova V.Z.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2018, Давудов М.М., Рагимов Ч.Р., Ахундов А.А., Аликулиев В.К., Сафаров Д.А., Османов Ш.Ш., Доброхотова В.З.</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="en">Davudov M.M., Rahimov C.R., Akhundov A.A., Alikuliev V.K., Safarov D.A., Osmanov S.S., Dobrokhotova V.Z.</copyright-holder><copyright-holder xml:lang="ru">Давудов М.М., Рагимов Ч.Р., Ахундов А.А., Аликулиев В.К., Сафаров Д.А., Османов Ш.Ш., Доброхотова В.З.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/376">https://ogsh.abvpress.ru/jour/article/view/376</self-uri><abstract xml:lang="en"><p><bold>The study objective</bold> is to report a case of mandibular ameloblastoma.</p><p><bold>Materials and methods</bold>. A 30-year-oldfemale patient presented with swelling of the right mandibular region that appeared 8 months ago and has been slowly increasing. The patient had no other symptoms, such as pain, anesthesia, paresthesia, difficulty swallowing, mouth opening, speech disorders, fever, chills, or weight loss. Orthopantomography revealed pronounced bone resorption in the right portion of the mandibular body. Computed tomography showed a cystic cavity in this area. After incisional biopsy, the patient was diagnosed with ameloblastic carcinoma. We performed segmental mandibular resection and installed a reconstructive plate to restore mandibular integrity. We also performed selective cervical lymph node dissection (levels Ia and Ib).</p><p><bold>Results.</bold> One yearpostoperatively, the results were considered aesthetically and functionally satisfactory.</p><p><bold>Conclusion.</bold> We observed an aggressive disease phenotype with extensive localized bone destruction, typical of ameloblastic carcinoma. Extensive excision of the primary tumor and selective cervical lymph node dissection without radiotherapy ensured a relapse-free period during patient’s follow up.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Цель исследования</bold> — описать клинический случай амелобластомы нижней челюсти.</p><p><bold>Материалы и методы</bold>. Больная 30 лет обратилась с основной жалобой на припухлость в правой половине нижней челюсти, которая возникла 8 мес назад и медленно увеличивалась. Никаких других симптомов, таких как боль, анестезия или парестезия, не наблюдалось, жалоб на затрудненное глотание, открывание рта, нарушения речи, лихорадку, озноб или потерю веса пациентка не предъявляла. На ортопантомограмме визуализирована выраженная многоячеистая резорбция тела нижней челюсти справа. При компьютерной томографии обнаружено кистозное образование в области тела нижней челюсти справа. Инцизионная биопсия позволила поставить гистопатологический диагноз амелобластической карциномы. Проведена сегментарная резекция нижней челюсти; для восстановления ее целостности установлена реконструктивная пластина. Выполнена селективная шейная лимфодиссекция в зонах Iа и Ib.</p><p><bold>Результаты.</bold> Спустя 1 год после операции результаты с эстетической и функциональной точки зрения признаны удовлетворительными.</p><p><bold>Заключение.</bold> В представленном клиническом случае отмечалась типичная для амелобластической карциномы агрессивность течения с обширным локальным разрушением кости. Широкое иссечение первичной опухоли и селективная шейная диссекция без радиотерапии обеспечили безрецидивное течение заболевания на период наблюдения.</p></trans-abstract><kwd-group xml:lang="en"><kwd>ameloblastoma</kwd><kwd>ameloblastic carcinoma</kwd><kwd>mandible</kwd><kwd>reconstructive surgery</kwd><kwd>cervical lymph node dissection</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>амелобластома</kwd><kwd>амелобластическая карцинома</kwd><kwd>нижняя челюсть</kwd><kwd>реконструктивная операция</kwd><kwd>шейная лимфодиссекция</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1.	Avon S.L., McComb J., Clokie C. Ameloblastic carcinoma: case report and literature review. J Can Dent Assoc 2003;69(9):573—6. PMID: 14653932.</mixed-citation><mixed-citation xml:lang="ru">Avon S.L., McComb J., Clokie C. Ameloblastic carcinoma: case report and literature review. 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