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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">38</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2013-0-1-39-42</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОРНЫЕ СТАТЬИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">DIAGNOSTIC ABILITIES OF THE ORAL FLUID IN ONCOLOGY</article-title><trans-title-group xml:lang="ru"><trans-title>ДИАГНОСТИЧЕСКАЯ ЗНАЧИМОСТЬ ИССЛЕДОВАНИЯ РОТОВОЙ ЖИДКОСТИ В ОНКОЛОГИИ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nikolenko</surname><given-names>V. N.</given-names></name><name xml:lang="ru"><surname>Николенко</surname><given-names>В. Н.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kozlov</surname><given-names>S. V.</given-names></name><name xml:lang="ru"><surname>Козлов</surname><given-names>С. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kochurova</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Кочурова</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>evkochurova@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО «Первый Московский государственный медицинский университет им. И.М. Сеченова» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2013</year></pub-date><volume>3</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>39</fpage><lpage>42</lpage><history><date date-type="received" iso-8601-date="2015-04-16"><day>16</day><month>04</month><year>2015</year></date><date date-type="accepted" iso-8601-date="2015-04-16"><day>16</day><month>04</month><year>2015</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, Nikolenko V.N., Kozlov S.V., Kochurova E.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, Николенко В.Н., Козлов С.В., Кочурова Е.В.</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">Nikolenko V.N., Kozlov S.V., Kochurova E.V.</copyright-holder><copyright-holder xml:lang="ru">Николенко В.Н., Козлов С.В., Кочурова Е.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/38">https://ogsh.abvpress.ru/jour/article/view/38</self-uri><abstract xml:lang="en"><p>The incidence of the population of Russia malignant tumors of maxillofacial region increase every year by 1.53%. Increase of morbidity for the period from 2000 to 2010 is 16.39%. A high level of prevalence can be included to the problem of early diagnosis. Detection of biomarkers in saliva has emerged as a novel approach for the diagnosis of malignant tumors of the oral cavity and its developmental stages including, initial process, invasion, recurrence and treatment.</p></abstract><trans-abstract xml:lang="ru"><p>Заболеваемость населения России злокачественными новообразованиями (ЗН) челюстно-лицевой области увеличивается каждый год на 1,53 %. Прирост за период с 2000 по 2010 г. составляет 16,39 %. Высокий уровень заболеваемости актуализирует проблему ранней диагностики. В этом плане определение биомаркеров в слюне является новым подходом к проблеме диагностики ЗН полости рта, стадий развития, включая начальный процесс, распространение, рецидив и лечение.</p></trans-abstract><kwd-group xml:lang="en"><kwd>salivary fluid</kwd><kwd>oncology</kwd><kwd>maxillofacial region</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ротовая жидкость</kwd><kwd>онкология</kwd><kwd>новообразования челюстно-лицевой области</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Petersen P.E. Strengthening the prevention of oral cancer: the WHO perspective. Community Dent Oral Epidemiol 2005;33(6):397–9.</mixed-citation><mixed-citation xml:lang="ru">Petersen P.E. Strengthening the prevention of oral cancer: the WHO perspective. 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