<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">393</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2019-9-1-85-92</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Elimination of extensive cranioorbitofacial defect after removal of myxofibrosarcoma (G2) with replacement of the hard palate and the alveolar process on the left: clinical case</article-title><trans-title-group xml:lang="ru"><trans-title>Комбинированное устранение обширного краниоороорбитофациального дефекта и реабилитация после удаления рецидивной миксофибросаркомы (g2) с вовлечением основания черепа: клинический пример</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2095-5931</contrib-id><name-alternatives><name xml:lang="en"><surname>Polyakov</surname><given-names>A. P.</given-names></name><name xml:lang="ru"><surname>Поляков</surname><given-names>А. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinsky Proezd, Moscow 125284.</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский пр., 3.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Zaitsev</surname><given-names>A. M.</given-names></name><name xml:lang="ru"><surname>Зайцев</surname><given-names>А. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinsky Proezd, Moscow 125284.</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский пр., 3.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kaprin</surname><given-names>A. D.</given-names></name><name xml:lang="ru"><surname>Каприн</surname><given-names>А. Д.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinsky Proezd, Moscow 125284.</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский пр., 3.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4293-2725</contrib-id><name-alternatives><name xml:lang="en"><surname>Ratushniy</surname><given-names>M. V.</given-names></name><name xml:lang="ru"><surname>Ратушный</surname><given-names>М. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinsky Proezd, Moscow 125284.</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский пр., 3.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1167-5372</contrib-id><name-alternatives><name xml:lang="en"><surname>Matorin</surname><given-names>O. V.</given-names></name><name xml:lang="ru"><surname>Маторин</surname><given-names>О. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinsky Proezd, Moscow 125284.</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский пр., 3.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3921-6872</contrib-id><name-alternatives><name xml:lang="en"><surname>Filyushin</surname><given-names>M. M.</given-names></name><name xml:lang="ru"><surname>Филюшин</surname><given-names>М. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinsky Proezd, Moscow 125284.</p></bio><bio xml:lang="ru"><p>Филюшин Михаил Михайлович.</p><p>125284 Москва, 2-й Боткинский пр., 3.</p></bio><email>filushin_m@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7854-9824</contrib-id><name-alternatives><name xml:lang="en"><surname>Rebrikova</surname><given-names>I. V.</given-names></name><name xml:lang="ru"><surname>Ребрикова</surname><given-names>И. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinsky Proezd, Moscow 125284.</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский пр., 3.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Sugaipov</surname><given-names>A. L.</given-names></name><name xml:lang="ru"><surname>Сугаипов</surname><given-names>А. Л.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinsky Proezd, Moscow 125284.</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский пр., 3.</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8500-8620</contrib-id><name-alternatives><name xml:lang="en"><surname>Mordovsky</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Мордовский</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2nd Botkinsky Proezd, Moscow 125284.</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский пр., 3.</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiology Center of the Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">Московский научно-исследовательский онкологический институт им. П.А. Герцена – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2019-04-03" publication-format="electronic"><day>03</day><month>04</month><year>2019</year></pub-date><volume>9</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>85</fpage><lpage>92</lpage><history><date date-type="received" iso-8601-date="2019-04-03"><day>03</day><month>04</month><year>2019</year></date><date date-type="accepted" iso-8601-date="2019-04-03"><day>03</day><month>04</month><year>2019</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2019, Polyakov A.P., Zaitsev A.M., Kaprin A.D., Ratushniy M.V., Matorin O.V., Filyushin M.M., Rebrikova I.V., Sugaipov A.L., Mordovsky A.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2019, Поляков А.П., Зайцев А.М., Каприн А.Д., Ратушный М.В., Маторин О.В., Филюшин М.М., Ребрикова И.В., Сугаипов А.Л., Мордовский А.В.</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="en">Polyakov A.P., Zaitsev A.M., Kaprin A.D., Ratushniy M.V., Matorin O.V., Filyushin M.M., Rebrikova I.V., Sugaipov A.L., Mordovsky A.V.</copyright-holder><copyright-holder xml:lang="ru">Поляков А.П., Зайцев А.М., Каприн А.Д., Ратушный М.В., Маторин О.В., Филюшин М.М., Ребрикова И.В., Сугаипов А.Л., Мордовский А.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/393">https://ogsh.abvpress.ru/jour/article/view/393</self-uri><abstract xml:lang="en"><p><bold>The study objective</bold> is to present the experience of performing extensive cranioorbital resection with subsequent arthroplasty of the hard palate and the dentition of the alveolar process of the maxilla.</p><p><bold>Materials and methods</bold>. In 2018, in the Department of Microsurgery of the P.A. Hertzen Moscow Oncology Research Institute, extensive cranioorbital surgery for recurrent sarcoma of the upper jaw was performed, after the treatment in other clinics. The extensive intervention included the exposure of the dura and the single-stage reconstruction of tissue defect, bone defect of the skull base by using the displaced aponeurotic flap of scalp and microsurgical reconstruction of the soft tissues of the face and mouth left free of the gastro-omental flap. In the early postoperative period, the patient underwent endoprosthesis replacement of the hard palate and alveolar process with a dentition. </p><p><bold>Results</bold>. Extensive intervention with resection of the structures cranioorbital zone and the skull base with a single-stage reconstruction with free gastro-omental flap with subsequent arthroplasty of the hard palate and the alveolar process dental arch allowed to rehabilitate the patient.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Цель исследования</bold> – представить опыт выполнения обширной краниоороорбитофациальной резекции с последующим эндопротезированием твердого неба и зубного ряда альвеолярного отростка верхней челюсти.</p><p><bold>Материалы и методы</bold>. В 2018 г. в отделении микрохирургии Московского научно-исследовательского онкологического института им. П.А. Герцена выполнено обширное краниоороорбитофациальное хирургическое вмешательство по поводу рецидивной саркомы верхней челюсти (после лечения в других учреждениях). Вмешательство включало обнажение твердой мозговой оболочки, одномоментную реконструкцию дефекта тканей и костей основания черепа перемещенным апоневротическим лоскутом скальпа, микрохирургическую реконструкцию мягких тканей лица и полости рта слева свободным желудочно-сальниковым лоскутом. В раннем послеоперационном периоде проведено эндопротезирование твердого неба и альвеолярного отростка с зубным рядом.</p><p><bold>Результаты</bold>. Обширное вмешательство с резекцией структур краниоороорбитофациальной зоны и основания черепа с одномоментной реконструкцией дефекта и последующим эндопротезированием позволило полостью реабилитировать пациента в социальном плане.</p></trans-abstract><kwd-group xml:lang="en"><kwd>cranioorbital tumor</kwd><kwd>endoprosthetics</kwd><kwd>jawbone cancer</kwd><kwd>free gastro-omental flap</kwd><kwd>autograft</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>опухоли краниоороорбитофациальной области</kwd><kwd>эндопротезирование</kwd><kwd>саркомы челюсти</kwd><kwd>свободный желудочно-сальниковый лоскут</kwd><kwd>аутотрансплантат</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Huang H.Y., Lal P., Qin J. et al. Low-grade myxofibrosarcoma: a clinicopathologic analysis of 49 cases treated at a single institution with simultaneous assessment of the efficacy of 3-tier and 4-tier grading systems. Hum Pathol 2004;35(5):612—21. PMID: 15138937.</mixed-citation></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Guidelines for pathoanatomical diagnosis of human tumors. Ed. by N.A. Kraevsky, A.V. Smolyannikov. Moscow: Meditsina, 1971. 496 p. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Руководство по патологоанатомической диагностике опухолей человека. Под ред. Н.А. Краевского, А.В. Смольянникова. M.: Медицина, 1971. 496 с.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><mixed-citation>Wada T., Hasegawa T., Nagoya S. et al. Myxofibrosarcoma with an infiltrative growth pattern: a case report. Jpn J Clin Oncol 2000;30(10):458-62. PMID: 11185894.</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Cante D., Franco P., Sciacero P. et al. Combined chemoradiation for head and neck region myxofibrosarcoma of the maxillary sinus. Tumori 2013;99(2):e80-3. DOI: 10.1700/1283.14214. PMID: 23748836.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Meis-Kindblom J.M., Kindblom L.G., Enzinger F.M. Sclerosing epithelioid fibrosarcoma. A variant of fibrosarcoma simulating carcinoma. Am J Surg Pathol 1995;19(9):979—93. PMID: 7661286.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Mentzel T., Calonje E., Wadden C. et al. Myxofibrosarcoma. Clinicopathologic analysis of 75 cases with emphasis on the low-grade variant. Am J Surg Pathol 1996;20(4):391—405. PMID: 8604805.</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Taghi A.S., Ali A., Kuchai R., Saleh H. Rare sarcoma presented as sinusitis. BMJ Case Rep 2012;2012. DOI: 10.1136/bcr-02-2012-5863. PMID: 22927267.</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Zagars G.K., Mullen J.R., Pollack A. Malignant fibrous histiocytoma: outcome and prognostic factors following conservation surgery and radiotherapy. Int J Radiat Oncol Biol Phys 1996;34(5):983—94.</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Merck C., Angervall L., Kindblom L.G., Oden A. Myxofibrosarcoma. A malignant soft tissue tumor of fibroblastic-histiocytic origin. A clinicopathologic and prognostic study of 110 cases using multivariate analysis. Acta Pathol Microbiol Immunol Scand Suppl 1983;282:1-40. PMID: 6444190.</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Kaya M., Wada T., Nagoya S. et al. MRI and histological evaluation of the infiltra-tive growth pattern 9 of myxofibrosarcoma. Skeletal Radiol 2008;37(12):1085—90. DOI: 10.1007/s00256-008-0542-4. PMID: 18629459.</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Antonescu C.R., Rosenblum M.K., Pereira P. et al. Sclerosing epithelioid fibrosarcoma: a study of 16 cases and confirmation of a clinicopathologically distinct tumor. Am J Surg Pathol 2001;25(6): 699-709. PMID: 11395547.</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Abdulkader I., Cameselle-Teijeiro J., Fraga M. et al. Sclerosing epithelioid fibrosarcoma primary of the bone. Int J Surg Pathol 2002;10(3):227-30. DOI: 10.1177/106689690201000313. PMID: 12232581.</mixed-citation></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">Sanfilippo R., Miceli R., Grosso F. et al. Myxofibrosarcoma: prognostic factors and survival in a series of patients treated at a single institution. Ann Surg Oncol 2011;18(3):720—5. DOI: 10.1245/s10434-010-1341-4. PMID: 20878245.</mixed-citation><mixed-citation xml:lang="ru">Sanfilippo R., Miceli R., Grosso F. et al. Myxofibrosarcoma: prognostic factors and survival in a series of patients treated at a single institution. Ann Surg Oncol 2011;18(3):720—5. DOI: 10.1245/s10434-010-1341-4. PMID: 20878245.</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><mixed-citation>Battiata A.P., Casler J. Sclerosing epithelioid fibrosarcoma: a case report. Ann Otol Rhinol Laryngol 2005;114(2):87—9. DOI: 10.1177/000348940511400201. PMID: 15757185.</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Diagnostic imaging: head and neck. Ed. by H.R. Harnsberger, R.H. Wiggins, P.A. Hudgins et al. Salt Lake City: Amirsys, 2004.</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>O’Brien J.E., Stout A.P. Malignant fibrous xanthomas. Cancer 1964;17:1445-55. PMID: 14223761.</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Nishio J., Iwasaki H., Nabeshima K., Naito M. Cytogenetics and molecular genetics of myxoid soft-tissue sarcomas. Genet Res Int 2011;497148. DOI: 10.4061/2011/497148. PMID: 22567356.</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Qiubei Z., Cheng L., Yaping X. et al. Myxofibrosarcoma of the sinus piriformis: case report and literature review. World J Surg Oncol 2012;10:245. DOI: 10.1186/1477-7819-10-245. PMID: 23152982.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>DeBree R., van der Valk P., Kuik D.J. et al. Prognostic factors in adult soft tissue sarcomas of the head and neck: a single-centre experience. Oral Oncol 2006;42(7):703—9. DOI: 10.1016/j.oraloncology.2005.11.009. PMID: 16529978.</mixed-citation></ref></ref-list></back></article>
