<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">46</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2014-0-2-33-36</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DIAGNOSIS AND TREATMENT OF HEAD AND NECK TUMORS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ ГОЛОВЫ И ШЕИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">TREATMENT POLICY FOR STAGES CT1–2CN0M0 ORAL SQUAMOUS CELL CARCINOMA</article-title><trans-title-group xml:lang="ru"><trans-title>ТАКТИКА ЛЕЧЕНИЯ ПЛОСКОКЛЕТОЧНОГО РАКА ПОЛОСТИ РТА СТАДИЙ СT1–2СN0M0</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gelfand</surname><given-names>I. M.</given-names></name><name xml:lang="ru"><surname>Гельфанд</surname><given-names>И. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>igorgelf@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Romanov</surname><given-names>I. S.</given-names></name><name xml:lang="ru"><surname>Романов</surname><given-names>И. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>Department of Oncology, Postgraduate Faculty</italic></p></bio><bio xml:lang="ru"><p><italic>Кафедра онкологии, факультет усовершенствования врачей</italic></p></bio><email>igorgelf@yandex.ru</email><xref ref-type="aff" rid="aff2"/><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Minkin</surname><given-names>A. U.</given-names></name><name xml:lang="ru"><surname>Минкин</surname><given-names>А. У.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>igorgelf@yandex.ru</email><xref ref-type="aff" rid="aff4"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow</institution></aff><aff><institution xml:lang="ru">ФГБНУ «Российский онкологический научный центр им. Н.Н. Блохина» РАМН, Москва</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences</institution></aff><aff><institution xml:lang="ru">ФГБНУ «Российский онкологический научный центр им. Н.Н. Блохина» РАМН, Москва</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">N.I. Pirogov Russian  National Research Medical University, Ministry of Health of Russia, Moscow</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России, Москва</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">Northern State Medical University, Arkhangelsk</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО «Северный государственный медицинский университет» Минздрава России, Архангельск</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2014-04-15" publication-format="electronic"><day>15</day><month>04</month><year>2014</year></pub-date><volume>4</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>33</fpage><lpage>36</lpage><history><date date-type="received" iso-8601-date="2015-04-16"><day>16</day><month>04</month><year>2015</year></date><date date-type="accepted" iso-8601-date="2015-04-16"><day>16</day><month>04</month><year>2015</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2014, Gelfand I.M., Romanov I.S., Minkin A.U.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2014, Гельфанд И.М., Романов И.С., Минкин А.У.</copyright-statement><copyright-year>2014</copyright-year><copyright-holder xml:lang="en">Gelfand I.M., Romanov I.S., Minkin A.U.</copyright-holder><copyright-holder xml:lang="ru">Гельфанд И.М., Романов И.С., Минкин А.У.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/46">https://ogsh.abvpress.ru/jour/article/view/46</self-uri><abstract xml:lang="en"><p><italic>The paper deals with the choice of treatment for oral squamous cell carcinoma: which of treatment options (surgery, radiation, or their combination) will be most suitable for squamous cell carcinoma of the mouth and tongue; how to affect regional metastatic regions in cN0.</italic></p></abstract><trans-abstract xml:lang="ru"><p><italic>Статья посвящена проблеме выбора лечения при плоскоклеточном раке слизистой оболочки полости рта: какой из методов лечения – хирургический, лучевая терапия или их комбинация – будет наиболее подходящим при плоскоклеточном раке слизистой оболочки полости рта и языка; как воздействовать на зоны регионарного метастазирования при сN0.</italic></p></trans-abstract><kwd-group xml:lang="en"><kwd>oral squamous cell carcinoma</kwd><kwd>preventive neck lymph node dissection</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>плоскоклеточный рак слизистой оболочки полости рта</kwd><kwd>профилактическая шейная лимфодиссекция</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Jemal A., Murray T., Ward E. et al. Cancer statistics, 2005. CA Cancer J Clin 2005;55:10–30.</mixed-citation><mixed-citation xml:lang="ru">Jemal A., Murray T., Ward E. et al. Cancer statistics, 2005. CA Cancer J Clin 2005;55:10–30.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">2. Anis R., Gaballah K. Oral cancer in the UAE: a multicenter, retrospective study. Libyan J Med 2013 Aug 27;8:21782.</mixed-citation><mixed-citation xml:lang="ru">Anis R., Gaballah K. Oral cancer in the UAE: a multicenter, retrospective study. Libyan J Med 2013 Aug 27;8:21782.</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">3. Давыдов М.И., Аксель Е.М. Статистика злокачественных новообразований в России и странах СНГ в 2010 г. М., 2012.</mixed-citation><mixed-citation xml:lang="ru">Давыдов М.И., Аксель Е.М. Статистика злокачественных новообразований в России и странах СНГ в 2010 г. М., 2012.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><citation-alternatives><mixed-citation xml:lang="en">4. Koch W.M. Head and neck cancer. Philadelphia, PA: Saunders/Elsevier, 2010.</mixed-citation><mixed-citation xml:lang="ru">Koch W.M. Head and neck cancer. Philadelphia, PA: Saunders/Elsevier, 2010.</mixed-citation></citation-alternatives></ref><ref id="B5"><label>5.</label><citation-alternatives><mixed-citation xml:lang="en">5. Пачес А.И., Ольшанский В.О., Любаев В.Л., Туок Т.Х. Злокачественные опухоли полости рта, глотки и гортани. М., 1988.</mixed-citation><mixed-citation xml:lang="ru">Пачес А.И., Ольшанский В.О., Любаев В.Л., Туок Т.Х. Злокачественные опухоли полости рта, глотки и гортани. М., 1988.</mixed-citation></citation-alternatives></ref><ref id="B6"><label>6.</label><citation-alternatives><mixed-citation xml:lang="en">6. Кицманюк З.Д., Чойнзонов Е.Л., Мусабаева Л.И., Новиков В.А. Тактика лечения рака гортани на современном этапе. Сиб онкол журн 2003;2:3–11.</mixed-citation><mixed-citation xml:lang="ru">Кицманюк З.Д., Чойнзонов Е.Л., Мусабаева Л.И., Новиков В.А. Тактика лечения рака гортани на современном этапе. Сиб онкол журн 2003;2:3–11.</mixed-citation></citation-alternatives></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">7. Kleiner D.E., Stetler-Stevenson W.G. Matrix metalloproteinases and metastasis. Cancer Chemother Pharmacol 1999;43 Suppl:S42–51.</mixed-citation><mixed-citation xml:lang="ru">Kleiner D.E., Stetler-Stevenson W.G. Matrix metalloproteinases and metastasis. Cancer Chemother Pharmacol 1999;43 Suppl:S42–51.</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">8. Wang C.C. Radiation therapy for head and neck neoplasms, 3rd ed. New York: Wiley-Liss, 1997. 9. Greene F. AJCC Cancer Staging Handbook. Chicago: Springer, 2002.</mixed-citation><mixed-citation xml:lang="ru">Wang C.C. Radiation therapy for head and neck neoplasms, 3rd ed. New York: Wiley-Liss, 1997. 9. Greene F. AJCC Cancer Staging Handbook. Chicago: Springer, 2002.</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">10. Rodgers L.W. Jr, Stringer S.P., Mendenhall W.M. e t a l . Management of squamous cell carcinoma of the floor of mouth. Head Neck 1993;15:16–9.</mixed-citation><mixed-citation xml:lang="ru">Rodgers L.W. Jr, Stringer S.P., Mendenhall W.M. e t a l . Management of squamous cell carcinoma of the floor of mouth. Head Neck 1993;15:16–9.</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><citation-alternatives><mixed-citation xml:lang="en">11. Sessions D.G., Spector G.J., Lenox J. et al. Analysis of treatment results for oral tongue cancer. Laryngoscope 2002;112(4):616–25.</mixed-citation><mixed-citation xml:lang="ru">Sessions D.G., Spector G.J., Lenox J. et al. Analysis of treatment results for oral tongue cancer. Laryngoscope 2002;112(4):616–25.</mixed-citation></citation-alternatives></ref><ref id="B11"><label>11.</label><citation-alternatives><mixed-citation xml:lang="en">12. Byers R.M., Newman R., Russell N. et al. Results of treatment for squamous carcinoma of the lower gum. Cancer 1981;47:2236–8.</mixed-citation><mixed-citation xml:lang="ru">Byers R.M., Newman R., Russell N. et al. Results of treatment for squamous carcinoma of the lower gum. Cancer 1981;47:2236–8.</mixed-citation></citation-alternatives></ref><ref id="B12"><label>12.</label><citation-alternatives><mixed-citation xml:lang="en">13. Byers R.M., Anderson B., Schwarz E.A. et al. Treatment of squamous cаrсinoma of the retromolar trigone. Am J Clin Oncol 1984;7(6):647–52.</mixed-citation><mixed-citation xml:lang="ru">Byers R.M., Anderson B., Schwarz E.A. et al. Treatment of squamous cаrсinoma of the retromolar trigone. Am J Clin Oncol 1984;7(6):647–52.</mixed-citation></citation-alternatives></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">14. Fein D.A., Mendenhall W.M., Parsons J.T. et al. Carcinoma of the oral tongue: a comparison of results and complications of treatment with radiotherapy and/or surgery. Head Neck 1994;16:358–65.</mixed-citation><mixed-citation xml:lang="ru">Fein D.A., Mendenhall W.M., Parsons J.T. et al. Carcinoma of the oral tongue: a comparison of results and complications of treatment with radiotherapy and/or surgery. Head Neck 1994;16:358–65.</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">15. Матякин Е.Г. Клинические аспекты регионарного метастазирования рака языка и гортани. Дис. … д-ра мед. наук. М., 1988.</mixed-citation><mixed-citation xml:lang="ru">Матякин Е.Г. Клинические аспекты регионарного метастазирования рака языка и гортани. Дис. … д-ра мед. наук. М., 1988.</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><citation-alternatives><mixed-citation xml:lang="en">16. Spiro R.H., Huvos A.G., Wong G.Y. et al. Predictive value of tumor thickness in squamous carcinoma confined to the tongue and floor of the mouth. Am J Surg 1986;152:345–50.</mixed-citation><mixed-citation xml:lang="ru">Spiro R.H., Huvos A.G., Wong G.Y. et al. Predictive value of tumor thickness in squamous carcinoma confined to the tongue and floor of the mouth. Am J Surg 1986;152:345–50.</mixed-citation></citation-alternatives></ref><ref id="B16"><label>16.</label><citation-alternatives><mixed-citation xml:lang="en">17. O-Charoenrat P., Pillai G., Patel S. et al. Tumour thickness predicts cervical nodal metastases and survival in early tongue cancer. Oral Oncol 2003;39:386–90.</mixed-citation><mixed-citation xml:lang="ru">O-Charoenrat P., Pillai G., Patel S. et al. Tumour thickness predicts cervical nodal metastases and survival in early tongue cancer. Oral Oncol 2003;39:386–90.</mixed-citation></citation-alternatives></ref><ref id="B17"><label>17.</label><citation-alternatives><mixed-citation xml:lang="en">18. Byers R.M., Weber R.S., Andrews T. et al. Frequency and therapeutic implications of «skip metastases» in the neck from squamous carcinoma of the oral tongue. Head Neck 1997;19:14–9.</mixed-citation><mixed-citation xml:lang="ru">Byers R.M., Weber R.S., Andrews T. et al. Frequency and therapeutic implications of «skip metastases» in the neck from squamous carcinoma of the oral tongue. Head Neck 1997;19:14–9.</mixed-citation></citation-alternatives></ref><ref id="B18"><label>18.</label><citation-alternatives><mixed-citation xml:lang="en">19. Hicks W.L. Jr, North J.H. Jr, Loree T.R. et al. Surgery as a single modality therapy for squamous cell carcinoma of the oral tongue. Am J Otolaryngol 1998;19:24–8.</mixed-citation><mixed-citation xml:lang="ru">Hicks W.L. Jr, North J.H. Jr, Loree T.R. et al. Surgery as a single modality therapy for squamous cell carcinoma of the oral tongue. Am J Otolaryngol 1998;19:24–8.</mixed-citation></citation-alternatives></ref></ref-list></back></article>
