Head and Neck TumorsHead and Neck TumorsОпухоли головы и шеи2222-14682411-4634Publishing House ABV Press5110.17650/2222-1468-2014-0-2-41-45REVIEWSОБЗОРНЫЕ СТАТЬИTHE ADVANTAGES OF SENTINEL LYMPH NODE BIOPSY OVER FUNCTIONAL NECK DISSECTION (A REVIEW OF LITERATURE)ПРЕИМУЩЕСТВА БИОПСИИ «СТОРОЖЕВОГО» ЛИМФАТИЧЕСКОГО УЗЛА ПЕРЕД ФАСЦИАЛЬНО‑ФУТЛЯРНЫМ ИССЕЧЕНИЕМ КЛЕТЧАТКИ ШЕИ (ОБЗОР ЛИТЕРАТУРЫ)RomanovI. S.РомановИ. С.
Russian Federation

Department of Head and Neck Tumors, Department of Oncology, Postgraduate Faculty

Отдел опухолей головы и шеи, кафедра онкологии, факультет усовершенствования врачей

drromanov@mail.ruShiryaеvS. V.ШиряевС. В.
Russian Federation

Department of Head and Neck Tumors

Отдел опухолей головы и шеи

drromanov@mail.ruVishnevskayaYa. V.ВишневскаяЯ. В.
Russian Federation

Department of Head and Neck Tumors

Отдел опухолей головы и шеи

drromanov@mail.ruN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical SciencesФГБНУ «Российский онкологический научный центр им. Н.Н. Блохина» РАМН, МоскваN.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia, MoscowГБОУ ВПО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России, МоскваN.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, MoscowФГБНУ «Российский онкологический научный центр им. Н.Н. Блохина» РАМН, Москва150420144241451604201516042015Copyright ©; 2014, Romanov I.S., Shiryaеv S.V., Vishnevskaya Y.V.Copyright ©; 2014, Романов И.С., Ширяев С.В., Вишневская Я.В.2014Romanov I.S., Shiryaеv S.V., Vishnevskaya Y.V.Романов И.С., Ширяев С.В., Вишневская Я.В.https://creativecommons.org/licenses/by/4.0https://ogsh.abvpress.ru/jour/article/view/51

The paper analyzes the data available in the literature on sentinel lymph node biopsy in patients with oral cancer and shows its advantages over prophylactic neck dissection: less pronounced functional and cosmetic consequences, the possibility of a detailed pathomorphological analysis of removed neck lymph nodes macrospecimens with immunohistochemical studies.

Проанализированы литературные данные о биопсии «сторожевого» лимфатического узла у больных раком полости рта и пока- заны ее преимущества перед превентивным фаcциально-футлярным иссечением клетчатки шеи: менее выраженные функцио- нальные и косметические последствия, возможность детального патоморфологического анализа удаленных макропрепаратов клетчатки шеи с иммуногистохимическими исследованиями.

guardian lymph node, oral cancer, fascial encasement excision of neck fatсторожевой лимфатический узел, рак полости рта, фасциально-футлярное иссечение клетчатки шеи1. Решетов И.В., Кравцов С.А., Маторин О.В. и др. Разработка методики определения «сторожевых» лимфатических узлов методом радиодетекции аппаратом РИГ-10П. Материалы X Российского онкологического конгресса. Москва, 21–23 ноября 2006 г. С. 198.Решетов И.В., Кравцов С.А., Маторин О.В. и др. Разработка методики определения «сторожевых» лимфатических узлов методом радиодетекции аппаратом РИГ-10П. Материалы X Российского онкологического конгресса. Москва, 21–23 ноября 2006 г. С. 198.2. Романов И.С., Оджарова А.А., Удинцов Д.Б. и др. Выявление «сторожевых» лимфатических узлов при плоскоклеточном раке полости рта с применением дооперационной лимфосцинтиграфии. Медицинская радиология и радиационная безопас- ность 2012;57(6):58–67.Романов И.С., Оджарова А.А., Удинцов Д.Б. и др. Выявление «сторожевых» лимфатических узлов при плоскоклеточном раке полости рта с применением дооперационной лимфосцинтиграфии. Медицинская радиология и радиационная безопас- ность 2012;57(6):58–67.3. Werner J.A., Davis R.K. Metastases in head and neck cancer. New York: Springer, 2004. P. 233.Werner J.A., Davis R.K. Metastases in head and neck cancer. New York: Springer, 2004. P. 233.4. Gould E.A., Winship T., Philbin P.H., Kerr H.H. Observations of a “sentinel node” in cancer of the parotid. Cancer 1960;13:77–8.Gould E.A., Winship T., Philbin P.H., Kerr H.H. Observations of a “sentinel node” in cancer of the parotid. Cancer 1960;13:77–8.5. Seaman W.B., Powers W.E. Studies on the distribution of radioactive colloidal gold in regional lymph nodes containing cancer. Cancer 1955;8:1044–6.Seaman W.B., Powers W.E. Studies on the distribution of radioactive colloidal gold in regional lymph nodes containing cancer. Cancer 1955;8:1044–6.6. Cabanas R.M. An approach for the treatment of penile carcinoma. Cancer 1977;39:456–66.Cabanas R.M. An approach for the treatment of penile carcinoma. Cancer 1977;39:456–66.7. Fiori-Ratti L., Ventura S., Senin U., Nardi S. Study of the lymphatic system of the head and neck with Au-198 in normal condition and in oncologic pathology. I. Lymphoscintigraphy of the tongue and floor of the mouth. Valsalva 1966; 42(4):182–212.Fiori-Ratti L., Ventura S., Senin U., Nardi S. Study of the lymphatic system of the head and neck with Au-198 in normal condition and in oncologic pathology. I. Lymphoscintigraphy of the tongue and floor of the mouth. Valsalva 1966; 42(4):182–212.8. Blakeslee D.B., Becker G.D., Simpson G.T. et al. Lymphoscintigraphy of the neck. Otolaryngol Head and Neck Surg 1985;93:361–5.Blakeslee D.B., Becker G.D., Simpson G.T. et al. Lymphoscintigraphy of the neck. Otolaryngol Head and Neck Surg 1985;93:361–5.9. Borgstein P.J., Pijpers R., Comans E.F. et al. Sentinel lymph node biopsy in breast cancer: Guidelines and pitfalls of lymphos- cintigraphy and gamma probe detection. J Am Coll Surg 1998;186(3):275–83.Borgstein P.J., Pijpers R., Comans E.F. et al. Sentinel lymph node biopsy in breast cancer: Guidelines and pitfalls of lymphos- cintigraphy and gamma probe detection. J Am Coll Surg 1998;186(3):275–83.10. Кукушкина М.Н., Коровин С.И., Солодянникова О.И. и др. Биопсия «сторожевых» лимфатических узлов при меланоме кожи. Клиническая онкология 2011;4(4):34–40.Кукушкина М.Н., Коровин С.И., Солодянникова О.И. и др. Биопсия «сторожевых» лимфатических узлов при меланоме кожи. Клиническая онкология 2011;4(4):34–40.11. Nathanson S.D., Nelson L., Karvelis K.C. Rates of flow of technetium- 99m-labeled human serum from peripheral injection sites to sentinel lymph nodes. Ann Surg Oncol 1996;3:329–35.Nathanson S.D., Nelson L., Karvelis K.C. Rates of flow of technetium- 99m-labeled human serum from peripheral injection sites to sentinel lymph nodes. Ann Surg Oncol 1996;3:329–35.12. Alex J.C., Krag D.N. The gamma-probe- guided resection of radiolabeled primary lymph nodes. Surg Oncol Clin N Am 1996;5(1):33–41.Alex J.C., Krag D.N. The gamma-probe- guided resection of radiolabeled primary lymph nodes. Surg Oncol Clin N Am 1996;5(1):33–41.13. Shoaib T., Soutar D.S., Prosser J.E. et al. A suggested method for sentinel node biopsy in squamous cell carcinoma of the head and neck. Head Neck 1999;21:728–33.Shoaib T., Soutar D.S., Prosser J.E. et al. A suggested method for sentinel node biopsy in squamous cell carcinoma of the head and neck. Head Neck 1999;21:728–33.14. Shoaib T., Soutar D.S., MacDonald D.G. et al. The accuracy of head and neck carcinoma sentinel lymph node biopsy in the clinically N0 neck. Cancer 2001;91: 2077–83.Shoaib T., Soutar D.S., MacDonald D.G. et al. The accuracy of head and neck carcinoma sentinel lymph node biopsy in the clinically N0 neck. Cancer 2001;91: 2077–83.15. Ross G.L., Shoaib T., Soutar D.S. et al. The First International Conference on Sentinel node biopsy in mucosal head and neck cancer and adoption of a multicenterRoss G.L., Shoaib T., Soutar D.S. et al. The First International Conference on Sentinel node biopsy in mucosal head and neck cancer and adoption of a multicentertrial protocol. Ann Surg Oncol 2002;9: 406–10.16. Alex J.C., Sasaki C.T., Krag D.N. et al. Sentinel lymph node radiolocalisation in head and neck squamous cell carcinoma. Laryngoscope 2000;110:198–203.Alex J.C., Sasaki C.T., Krag D.N. et al. Sentinel lymph node radiolocalisation in head and neck squamous cell carcinoma. Laryngoscope 2000;110:198–203.17. Pitman K.T., Johnson J.T., Edington H. et al. Lymphatic mapping with isosulfan blue dye in squamous cell carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg 1998;124:790–3.Pitman K.T., Johnson J.T., Edington H. et al. Lymphatic mapping with isosulfan blue dye in squamous cell carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg 1998;124:790–3.18. Chiesa F., Mauri S., Grana C. et al. Is there a role for sentinel node biopsy in early N0 tongue tumors? Surgery 2000;128:16–21.Chiesa F., Mauri S., Grana C. et al. Is there a role for sentinel node biopsy in early N0 tongue tumors? Surgery 2000;128:16–21.19. Zitsch R.P. III, Todd D.W., Renner G.J., Singh A. Intraoperative radiolympho- scintigraphy for detection of occult nodal metastasis in patients with head and neck squamous cell carcinoma. Otolaryngol Head Neck Surg 2000;122:662–6.Zitsch R.P. III, Todd D.W., Renner G.J., Singh A. Intraoperative radiolympho- scintigraphy for detection of occult nodal metastasis in patients with head and neck squamous cell carcinoma. Otolaryngol Head Neck Surg 2000;122:662–6.20. Barzan L., Sulfaro S., Albert F. et al. Gamma probe accuracy in detecting the sentinel lymph node in clinically N0 squamous cell carcinoma of the head and neck. Ann Otol Rhinol Laryngol 2002;111:794–8.Barzan L., Sulfaro S., Albert F. et al. Gamma probe accuracy in detecting the sentinel lymph node in clinically N0 squamous cell carcinoma of the head and neck. Ann Otol Rhinol Laryngol 2002;111:794–8.21. Werner J.A., Dünne A.A., Ramaswamy A. et al. The sentinel node concept in head and neck cancer: Solution for the controversies in the N0 neck? Head Neck 2004;7:603–11.Werner J.A., Dünne A.A., Ramaswamy A. et al. The sentinel node concept in head and neck cancer: Solution for the controversies in the N0 neck? Head Neck 2004;7:603–11.22. Paleri V., Rees G., Arullendran P. et al. Sentinel node biopsy in squamous cell cancer of the oral cavity and oral pharynx: a diagnostic meta-analysis. Head Neck 2005;27:739–47.Paleri V., Rees G., Arullendran P. et al. Sentinel node biopsy in squamous cell cancer of the oral cavity and oral pharynx: a diagnostic meta-analysis. Head Neck 2005;27:739–47.23. Ross G.L., Soutar D.S., MacDonald D.G. et al. Sentinel node biopsy in head and neck cancer: preliminary results of a multicenter trial. Ann Surg Oncol 2004;11:690–6.Ross G.L., Soutar D.S., MacDonald D.G. et al. Sentinel node biopsy in head and neck cancer: preliminary results of a multicenter trial. Ann Surg Oncol 2004;11:690–6.24. Civantos F.J., Moffat F.I., Goodwin W.J. Lymphatic mapping and sentinel lymphadenectomy for 106 head and neck lesions: contrasts between oral cavity and cutaneous malignancy. Laryngoscope 2006;16:1–15.Civantos F.J., Moffat F.I., Goodwin W.J. Lymphatic mapping and sentinel lymphadenectomy for 106 head and neck lesions: contrasts between oral cavity and cutaneous malignancy. Laryngoscope 2006;16:1–15.25. Stoeckli S.J. Sentinel node biopsy for oral and oropharyngeal squamous cell carcinoma of the head and neck. Laryngoscope 2007;117:1539–51.Stoeckli S.J. Sentinel node biopsy for oral and oropharyngeal squamous cell carcinoma of the head and neck. Laryngoscope 2007;117:1539–51.26. Civantos F. Jr, Zitsch R., Bared A. et al. Sentinel node biopsy for squamous cell carcinoma of the head and neck. J Surg Oncol 2008;97:683–90.Civantos F. Jr, Zitsch R., Bared A. et al. Sentinel node biopsy for squamous cell carcinoma of the head and neck. J Surg Oncol 2008;97:683–90.27. Andy K., Schilling C., Gurney B., McGurk M. Interim results of the Sentinel European node trial(SENT). Abstracts for the 5th European Conference on Head and Neck Oncology 18–21 April 2012 in Poznan, Poland. Eur Arch Otorhinolaryngol 2012;269(4):1332.Andy K., Schilling C., Gurney B., McGurk M. Interim results of the Sentinel European node trial(SENT). Abstracts for the 5th European Conference on Head and Neck Oncology 18–21 April 2012 in Poznan, Poland. Eur Arch Otorhinolaryngol 2012;269(4):1332.28. Schiefke F., Akdemir M., Weber A. et al. Function, postoperative morbidity, and quality of life after cervical sentinel node biopsy and after selective neck dissection. Head Neck 2009;31: 503–12.Schiefke F., Akdemir M., Weber A. et al. Function, postoperative morbidity, and quality of life after cervical sentinel node biopsy and after selective neck dissection. Head Neck 2009;31: 503–12.29. Lawson G., Kesch S., Matar N. et al. Functional sequelae and quality of life after sentinel node excision versus modified radical neck dissection in patients with oropharyngeal and supraglottic cancer with clinically negative neck. 4th World Congress of International Federation of Head and Neck Oncologic Societies “Shifting Paradigms in Head and Neck Oncology”. June 15–19, 2010, Seoul, Korea. Abstract book, p. 217. 30. Rogers S.N., Ferlito A., Pelliteri P.K. et al. Quality of life following neck dissections(review). Acta Otolaryngol 2004;124:231–6.Lawson G., Kesch S., Matar N. et al. Functional sequelae and quality of life after sentinel node excision versus modified radical neck dissection in patients with oropharyngeal and supraglottic cancer with clinically negative neck. 4th World Congress of International Federation of Head and Neck Oncologic Societies “Shifting Paradigms in Head and Neck Oncology”. June 15–19, 2010, Seoul, Korea. Abstract book, p. 217. 30. Rogers S.N., Ferlito A., Pelliteri P.K. et al. Quality of life following neck dissections(review). Acta Otolaryngol 2004;124:231–6.31. Terrell J.E., Chepeha D.B. Clinical predictors of quality of life in patients with head and neck cancer. Arch Otolaryngol Head Neck Surg 2004;130:401–8.Terrell J.E., Chepeha D.B. Clinical predictors of quality of life in patients with head and neck cancer. Arch Otolaryngol Head Neck Surg 2004;130:401–8.32. Chepeha D.B., Taylor R.J., Chepeha J.C. et al. Functional assessment using Constant’s Shoulder scale after modified radical and selective neck dissection. Head Neck 2002;24:432–6.Chepeha D.B., Taylor R.J., Chepeha J.C. et al. Functional assessment using Constant’s Shoulder scale after modified radical and selective neck dissection. Head Neck 2002;24:432–6.33. Kuntz A.L., Weymuller E.A. Jr. Impact of neck dissection on quality of life. Laryngoscope 1999;109:1334–8.Kuntz A.L., Weymuller E.A. Jr. Impact of neck dissection on quality of life. Laryngoscope 1999;109:1334–8.34. Byers R.M., Weber R.S., Andrews T. et al. Frequency and therapeutic implications of ‘skip metastases’ in the neck from squamous cell carcinoma of the oral tongue. Head Neck 1997;19:14–9.Byers R.M., Weber R.S., Andrews T. et al. Frequency and therapeutic implications of ‘skip metastases’ in the neck from squamous cell carcinoma of the oral tongue. Head Neck 1997;19:14–9.35. Woolgar J.A., Rogers S.N., Lowe D. et al. Cervical lymph node metastasis in oral cancer: the importance of even microscopic extracapsular spread. Oral Oncol 2003;39:130–7.Woolgar J.A., Rogers S.N., Lowe D. et al. Cervical lymph node metastasis in oral cancer: the importance of even microscopic extracapsular spread. Oral Oncol 2003;39:130–7.36. Stoeckli J., Pfaltz M., Steinert H. et al. Histopathological features of occult metastasis detected by sentinel lymph node biopsy in oral and oropharyngeal squamous cell carcinoma. Laryngoscope 2002;112:111–5.Stoeckli J., Pfaltz M., Steinert H. et al. Histopathological features of occult metastasis detected by sentinel lymph node biopsy in oral and oropharyngeal squamous cell carcinoma. Laryngoscope 2002;112:111–5.37. Atula T., Hunter K.D., Cooper L.A. et al. Micrometastases, and isolated tumour cells in sentinel lymph nodes in oral and oropharyngeal squamous cell carcinoma. EJSO 2009;35:532–8.Atula T., Hunter K.D., Cooper L.A. et al. Micrometastases, and isolated tumour cells in sentinel lymph nodes in oral and oropharyngeal squamous cell carcinoma. EJSO 2009;35:532–8.38. The National Comprehensive Cancer Network. NCCN Practice Guidelines for Cancer of the Head and Neck, version 1.2000. Rockville, PA: The National Comprehensive Cancer Network, Inc.; 2000.The National Comprehensive Cancer Network. NCCN Practice Guidelines for Cancer of the Head and Neck, version 1.2000. Rockville, PA: The National Comprehensive Cancer Network, Inc.; 2000.39. Stoeckli S.J., Pfaltz M., Ross G.L. et al. The second international conference on sen- tinel node biopsy in mucosal head and neck cancer. Ann Surg Oncol 2005;12(11):919–24.Stoeckli S.J., Pfaltz M., Ross G.L. et al. The second international conference on sen- tinel node biopsy in mucosal head and neck cancer. Ann Surg Oncol 2005;12(11):919–24.