Head and Neck TumorsHead and Neck TumorsОпухоли головы и шеи2222-14682411-4634Publishing House ABV Press52510.17650/2222-1468-2020-10-2-38-45ORIGINAL REPORTОРИГИНАЛЬНОЕ ИССЛЕДОВАНИЕPossibilities of magnetic resonance imaging in SWI mode in differential diagnosis of brain gliomas (G3–G4) and primary lymphomasВозможности магнитно-резонансной томографии в режиме SwI в дифференциальной диагностике глиом (g3–g4) и первичных лимфом головного мозгаhttps://orcid.org/0000-0003-0431-2610SashinD. V.СашинД. В.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478

Денис Вячеславович Сашин

115478 Москва, Каширское шоссе, 24

denchegs70@gmail.comhttps://orcid.org/0000-0003-3930-5998DolgushinM. B.ДолгушинМ. Б.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478

115478 Москва, Каширское шоссе, 24

https://orcid.org/0000-0001-8347-1243KobyakovaE. A.КобяковаЕ. А.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478

115478 Москва, Каширское шоссе, 24

https://orcid.org/0000-0002-4160-9598BekyashevA. Kh.БекяшевА. Х.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478

115478 Москва, Каширское шоссе, 24

https://orcid.org/0000-0002-4648-2362SubbotinA. S.СубботинА. С.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478

115478 Москва, Каширское шоссе, 24

https://orcid.org/0000-0002-3785-7070NechipayE. A.НечипайЭ. А.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478

115478 Москва, Каширское шоссе, 24

https://orcid.org/0000-0003-3942-4102RomanovD. S.РомановД. С.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478

115478 Москва, Каширское шоссе, 24

https://orcid.org/0000-0003-3852-3969KozlovN. A.КозловН. А.
Russian Federation

24 Kashirskoe Shosse, Moscow 115478

115478 Москва, Каширское шоссе, 24

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России2407202010238452407202024072020Copyright ©; 2020, Sashin D.V., Dolgushin M.B., Kobyakova E.A., Bekyashev A.K., Subbotin A.S., Nechipay E.A., Romanov D.S., Kozlov N.A.Copyright ©; 2020, Сашин Д.В., Долгушин М.Б., Кобякова Е.А., Бекяшев А.Х., Субботин А.С., Нечипай Э.А., Романов Д.С., Козлов Н.А.2020Sashin D.V., Dolgushin M.B., Kobyakova E.A., Bekyashev A.K., Subbotin A.S., Nechipay E.A., Romanov D.S., Kozlov N.A.Сашин Д.В., Долгушин М.Б., Кобякова Е.А., Бекяшев А.Х., Субботин А.С., Нечипай Э.А., Романов Д.С., Козлов Н.А.https://creativecommons.org/licenses/by/4.0https://ogsh.abvpress.ru/jour/article/view/525

The study objective is to assess the possibilities of magnetic resonance imaging (MRI) in SWI (susceptibility weighted imaging) in the differential diagnosis of glial brain tumors and primary brain lymphomas. Materials and methods. Fifty-four patients with brain tumors were studied (men – 27 (50 %), women – 27 (50 %)). Average age 57.9 years. Histological examination of the surgical material revealed the glial nature of tumors in 41 patients (26 of them with glioblastoma, anaplastic astrocytomas – 15), primary brain lymphomas – in 13 patients. Brain MRI was performed using tomographs with a magnetic field of 3 and 1.5 T. A semi-quantitative assessment of the data obtained in the SWI mode based on the classification of ITSS (intratumoral susceptibility signals), reflecting the severity of interstitial vascular architectonics and microbleeding. Results. The degree of ITSS was 3 in glioblastomas (G4 ) in 26 (100 %) cases, in the structure of gliomas (G3 ) the ITSS values were 3 in 3 (20 %) cases, in the remaining 12 (80 %) cases – ITSS 2. In the group of primary brain lymphomas, the ITSS 1 was in 4 (30.7 %) cases, ITSS 0 was in 9 (69.3 %) cases. Conclusion. MRI in SWI mode is a promising technique that allows one to quantify the degree of pathological changes in tumor vascular architectonics and intratumoral hemorrhages and has shown high specificity in the differential diagnosis of malignant gliomas and lymphomas of the brain, accompanied by active accumulation of contrast medium.

Цель исследования – оценка возможностей магнитно-резонансной томографии (МРТ) в режиме SWI (susceptibility weighted imaging, изображения, взвешенные по магнитной восприимчивости) в дифференциальной диагностике глиом и первичных лимфом головного мозга. Материалы и методы. Обследованы 54 пациента (27 (50 %) мужчин, 27 (50 %) женщин, средний возраст 57,9 года) с объемными образованиями головного мозга. При гистологическом исследовании операционного материала верифицированы опухоли глиальной природы у 41 пациента (глиобластомы – у 26, анапластические астроцитомы – у 15) и первичные лимфомы головного мозга у 13 пациентов. МРТ головного мозга проводили на томографах с индукцией магнитного поля 3 и 1,5 Тл. Проведена полуколичественная оценка данных МРТ в режиме SWI на основе наличия ITSS (intratumoral susceptibility signals, внутриопухолевые сигналы восприимчивости), отражающих выраженность нарушений внутритканевой сосудистой архитектоники и наличие микрокровоизлияний. Результаты. Изменения, соответствующие ITSS 3, в глиобластомах (G4 ) выявлены во всех 26 (100 %) случаях, в структуре глиом (G3 ) в 3 (20 %) наблюдениях выявлены изменения, соответствующие ITSS 3, в остальных 12 (80 %) случаях – ITSS 2. В структуре лимфом головного мозга изменения, соответствующие ITSS 1, обнаружены в 4 (30,7 %) случаях, ITSS 0 – в 9 (69,3 %). Заключение. МРТ в режиме SWI представляется перспективным методом количественной оценки патологических изменений опухолевой сосудистой архитектоники и интратуморальных кровоизлияний благодаря высокой специфичности в дифференциальной диагностике злокачественных глиом и лимфом головного мозга, активно накапливающих контрастное вещество.

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