Head and Neck TumorsHead and Neck TumorsОпухоли головы и шеи2222-14682411-4634Publishing House ABV Press56310.17650/2222-1468-2020-10-3-72-80REVIEWSОБЗОРНЫЕ СТАТЬИOral mucositis in patients with oncological pathology of the oropharyngeal region: reviewОральные мукозиты у пациентов с онкологической патологией орофарингеальной области: обзор литературыhttps://orcid.org/0000-0002-7634-1384EreminaA. O.ЕрёминаА. О.
Russian Federation

6 Miklukho-Maklaya St., Moscow 117198

Александра Олеговна Ерёмина

117198 Москва, ул. Миклухо-Маклая, 6

 

sas1.91@mail.ruhttps://orcid.org/0000-0003-0183-4827ZaderenkoI. A.ЗадеренкоИ. А.
Russian Federation

6 Miklukho-Maklaya St., Moscow 117198, 

24 Kashirskoe Hwy, Moscow 115478

117198 Москва, ул. Миклухо-Маклая, 6, 

115478 Москва, Каширское шоссе, 24

https://orcid.org/0000-0001-5458-0192IvanovS. Yu.ИвановС. Ю.
Russian Federation

6 Miklukho-Maklaya St., Moscow 117198,

Bld. 4, 2 Bolshaya Pirogovskaya St., Moscow 119991

117198 Москва, ул. Миклухо-Маклая, 6, 

119991 Москва, ул. Большая Пироговская, 2, стр. 4

https://orcid.org/0000-0002-6835-5567AlievaS. B.АлиеваС. Б.
Russian Federation

24 Kashirskoe Hwy, Moscow 115478

115478 Москва, Каширское шоссе, 24

https://orcid.org/0000-0001-8980-6235DymnikovA. B.ДымниковА. Б.
Russian Federation

6 Miklukho-Maklaya St., Moscow 117198

117198 Москва, ул. Миклухо-Маклая, 6

https://orcid.org/0000-0003-1673-7261KhromushinaA. V.ХромушинаА. В.
Russian Federation

6 Miklukho-Maklaya St., Moscow 117198

117198 Москва, ул. Миклухо-Маклая, 6

https://orcid.org/0000-0003-1448-1733PkheshkhovaB. C.ПхешховаБ. Г.
Russian Federation

24 Kashirskoe Hwy, Moscow 115478

115478 Москва, Каширское шоссе, 24

RUDN UniversityФГАОУ ВО «Российский университет дружбы народов»N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of RussiaФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава РоссииI.M. Sechenov First Moscow State Medical University, Ministry of Health of RussiaФГАОУ ВО Первый Московский государственный медицинский университет им. И.М. Сеченова Минздрава России1611202010372801611202016112020Copyright ©; 2020, Eremina A.O., Zaderenko I.A., Ivanov S.Y., Alieva S.B., Dymnikov A.B., Khromushina A.V., Pkheshkhova B.C.Copyright ©; 2020, Ерёмина А.О., Задеренко И.А., Иванов С.Ю., Алиева С.Б., Дымников А.Б., Хромушина А.В., Пхешхова Б.Г.2020Eremina A.O., Zaderenko I.A., Ivanov S.Y., Alieva S.B., Dymnikov A.B., Khromushina A.V., Pkheshkhova B.C.Ерёмина А.О., Задеренко И.А., Иванов С.Ю., Алиева С.Б., Дымников А.Б., Хромушина А.В., Пхешхова Б.Г.https://creativecommons.org/licenses/by/4.0https://ogsh.abvpress.ru/jour/article/view/563

Oral mucositis is one of the most common effects of chemoradiotherapy in patients with oropharyngeal cancer. The development of oral mucositis is the main cause of interruption of antitumor therapy, which significantly affects the results of treatment of the main disease. Despite the fact that the disease is well studied in the literature, today there is no universal treatment and prevention protocol. The aim of this review is to analyze scientific publications devoted to the problems of etiology, pathogenesis, clinic, diagnosis, treatment and prevention of oral mucositis.

Оральный мукозит – одно из наиболее частых последствий химиолучевой терапии у пациентов с раком орофарингеальной области. Именно развитие орального мукозита считается основной причиной прерывания противоопухолевой терапии, которое значительно ухудшает результаты лечения онкологического заболевания. Несмотря на то что заболевание хорошо изучено, на сегодняшний день не разработан универсальный общепринятый алгоритм его лечения и профилактики. В данном обзоре представлен анализ научных публикаций, посвященных проблемам этиологии, патогенеза, клинической картины, диагностики, лечения и профилактики орального мукозита.

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