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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">723</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2021-11-4-110-118</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>REVIEW</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ОБЗОРНАЯ СТАТЬЯ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Neuroendocrine cancer of maxillary sinus: case report and literature review</article-title><trans-title-group xml:lang="ru"><trans-title>Нейроэндокринный рак верхнечелюстной пазухи: клинический случай и краткий обзор литературы</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3371-7548</contrib-id><name-alternatives><name xml:lang="en"><surname>Deshkina</surname><given-names>T. I.</given-names></name><name xml:lang="ru"><surname>Дешкина</surname><given-names>Т. И.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Tatyana Igorevna Deshkina</p><p>3 2<sup>nd </sup>Botkinsky Dr., Moscow 125284</p></bio><bio xml:lang="ru"><p>Татьяна Игоревна Дешкина</p><p>125284 Москва, 2-й Боткинский пр-д, 3</p></bio><email>rew9@yandex.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4879-2687</contrib-id><name-alternatives><name xml:lang="en"><surname>Bolotina</surname><given-names>L. V.</given-names></name><name xml:lang="ru"><surname>Болотина</surname><given-names>Л. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2<sup>nd </sup>Botkinsky Dr., Moscow 125284</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский пр-д, 3</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9181-7811</contrib-id><name-alternatives><name xml:lang="en"><surname>Gevorkov</surname><given-names>A. R.</given-names></name><name xml:lang="ru"><surname>Геворков</surname><given-names>А. Р.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2<sup>nd </sup>Botkinsky Dr., Moscow 125284</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский пр-д, 3</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1766-0059</contrib-id><name-alternatives><name xml:lang="en"><surname>Boyko</surname><given-names>A. V.</given-names></name><name xml:lang="ru"><surname>Бойко</surname><given-names>А. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2<sup>nd </sup>Botkinsky Dr., Moscow 125284</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский пр-д, 3</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2674-0416</contrib-id><name-alternatives><name xml:lang="en"><surname>Surkova</surname><given-names>V. S.</given-names></name><name xml:lang="ru"><surname>Суркова</surname><given-names>В. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2<sup>nd </sup>Botkinsky Dr., Moscow 125284</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский пр-д, 3</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5999-3164</contrib-id><name-alternatives><name xml:lang="en"><surname>Sedova</surname><given-names>M. V.</given-names></name><name xml:lang="ru"><surname>Седова</surname><given-names>М. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2<sup>nd </sup>Botkinsky Dr., Moscow 125284</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский пр-д, 3</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2095-5931</contrib-id><name-alternatives><name xml:lang="en"><surname>Polyakov</surname><given-names>A. P.</given-names></name><name xml:lang="ru"><surname>Поляков</surname><given-names>А. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2<sup>nd </sup>Botkinsky Dr., Moscow 125284</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский пр-д, 3</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0092-0459</contrib-id><name-alternatives><name xml:lang="en"><surname>Kornietskaya</surname><given-names>A. L.</given-names></name><name xml:lang="ru"><surname>Корниецкая</surname><given-names>А. Л.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2<sup>nd </sup>Botkinsky Dr., Moscow 125284</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский пр-д, 3</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4927-5585</contrib-id><name-alternatives><name xml:lang="en"><surname>Fedenko</surname><given-names>A. A.</given-names></name><name xml:lang="ru"><surname>Феденко</surname><given-names>А. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>3 2<sup>nd </sup>Botkinsky Dr., Moscow 125284</p></bio><bio xml:lang="ru"><p>125284 Москва, 2-й Боткинский пр-д, 3</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">P. Hertzen Moscow Oncology Research Institute – branch of National Medical Research Radiology Center, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">Московский научно-исследовательский онкологический институт им. П. А. Герцена – филиал ФГБУ «Национальный медицинский исследовательский центр радиологии» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2021-12-14" publication-format="electronic"><day>14</day><month>12</month><year>2021</year></pub-date><volume>11</volume><issue>4</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>110</fpage><lpage>118</lpage><history><date date-type="received" iso-8601-date="2022-02-14"><day>14</day><month>02</month><year>2022</year></date><date date-type="accepted" iso-8601-date="2022-02-14"><day>14</day><month>02</month><year>2022</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2021, Deshkina T.I., Bolotina L.V., Gevorkov A.R., Boyko A.V., Surkova V.S., Sedova M.V., Polyakov A.P., Kornietskaya A.L., Fedenko A.A.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2021, Дешкина Т.И., Болотина Л.В., Геворков А.Р., Бойко А.В., Суркова В.С., Седова М.В., Поляков А.П., Корниецкая А.Л., Феденко А.А.</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="en">Deshkina T.I., Bolotina L.V., Gevorkov A.R., Boyko A.V., Surkova V.S., Sedova M.V., Polyakov A.P., Kornietskaya A.L., Fedenko A.A.</copyright-holder><copyright-holder xml:lang="ru">Дешкина Т.И., Болотина Л.В., Геворков А.Р., Бойко А.В., Суркова В.С., Седова М.В., Поляков А.П., Корниецкая А.Л., Феденко А.А.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/723">https://ogsh.abvpress.ru/jour/article/view/723</self-uri><abstract xml:lang="en"><p>Malignant tumors of the sinuses and nasal cavity are rare diseases. Squamous cell carcinoma is the most common histological type (55–70 % of tumors of the sinuses and nasal cavity). The frequency of neuroendocrine tumors reaches 5 %. Currently, there is no generally accepted standard for the treatment of neuroendocrine tumors of sinonasal localization. If surgical treatment is associated with a significant deterioration of the quality of life or poor outcomes, chemoradiotherapy can be recommended. This article describes a clinical case of combined treatment of neuroendocrine cancer of the maxillary sinus and brief review of the literature on malignant tumors of the paranasal sinuses and the nasal cavity.</p></abstract><trans-abstract xml:lang="ru"><p>Злокачественные опухоли придаточных пазух и полости носа являются редким заболеванием. Их типичная гистологическая структура представлена плоскоклеточным раком, на долю которого приходится 55–70 % случаев всех злокачественных новообразований. Частота нейроэндокринных опухолей не превышает 5 %. В настоящий момент не существует общепринятого стандарта терапии нейроэндокринных опухолей синоназальной локализации. если хирургическое лечение сопряжено с существенным ухудшением качества жизни и/ или неблагоприятным прогнозом и выполнение инвалидизирующих операций на 1-м этапе не оправдано, пациентам может быть рекомендована химиолучевая терапия. В данной статье приводится описание клинического случая комбинированного лечения нейроэндокринного рака верхнечелюстной пазухи, а также краткий обзор литературы, посвященной злокачественным опухолям придаточных пазух и полости носа.</p></trans-abstract><kwd-group xml:lang="en"><kwd>neuroendocrine cancer</kwd><kwd>sinonasal carcinoma</kwd><kwd>maxillary sinus cancer</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>нейроэндокринный рак</kwd><kwd>синоназальная карцинома</kwd><kwd>рак верхнечелюстной пазухи</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">1. Thompson L.D.R. Sinonasal carcinomas. Current Diagnostic Pathol 2006;12:40–53. DOI: 10.1016/j.cdip.2005.10.009.</mixed-citation><mixed-citation xml:lang="ru">Thompson L.D.R. Sinonasal carcinomas. Current Diagnostic Pathol 2006;12:40–53. 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