Head and Neck TumorsHead and Neck TumorsОпухоли головы и шеи2222-14682411-4634Publishing House ABV Press8210.17650/2222-1468-2012-0-3-39-41NEUROONCOLOGY: DIAGNOSIS AND TREATMENT OF HEAD AND NECK TU MORSНЕЙРООНКОЛОГИЯ: ДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ ГОЛОВЫ И ШЕИEXPERIENCE WITH SURGICAL TREATMENT IN PATIENTS WITH LYMPHOPROLIFERATIVE LESION IN THE BRAIN AND SKULL VAULT BONESОПЫТ ХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ БОЛЬНЫХ С ЛИМФОПРОЛИФЕРАТИВНЫМ ПОРАЖЕНИЕМ ГОЛОВНОГО МОЗГА И КОСТЕЙ СВОДА ЧЕРЕПАMoldovanovD. A.МолдовановВ. А.
Russian Federation
MaslennikovaE. N.МасленниковаЕ. Н.
Russian Federation
YakovlenkoYu. G.ЯковленкоЮ. Г.
Russian Federation
dmaacm@rambler.ruTushevA. A.ТушевА. А.
Russian Federation
Rostov State Medical University, Ministry of Health of RussiaГБОУ ВПО «Ростовский государственный медицинский университет» Минздрава России, Ростов-на-ДонуRostov Regional Consulting-Diagnostic Center, Rostov-on-DonГАУ Ростовской области «Областной консультативно-диагностический центр», Ростов-на-Дону150420122339411804201518042015Copyright ©; 2012, Moldovanov D.A., Maslennikova E.N., Yakovlenko Y.G., Tushev A.A.Copyright ©; 2012, Молдованов В.А., Масленникова Е.Н., Яковленко Ю.Г., Тушев А.А.2012Moldovanov D.A., Maslennikova E.N., Yakovlenko Y.G., Tushev A.A.Молдованов В.А., Масленникова Е.Н., Яковленко Ю.Г., Тушев А.А.https://creativecommons.org/licenses/by/4.0https://ogsh.abvpress.ru/jour/article/view/82

The problem of lymphoproliferative lesions of the central nervous system (CNS) is urgent in both patients with immunodeficiency states and those without background systemic pathology in spite of the fact that the statistics vary greatly in these two categories. Despite a wide range of noninvasive diagnostic procedures, it is impossible to obtain a significant confirmation of primary lymphoproliferative CNS lesion in patients with no background systemic manifestations of the disease. Stereotactic biopsy, followed by combination chemo- and radiotherapy in accordance with the existing protocols, is a well-known procedure to treat suspected primary CNS lymphoma. This paper describes 4 cases of primary CNS and skull bone lymphomas in patients operated on for skull bone granuloma (in one case) or rapid progression of focal and global cerebral neurological deficit (in 3 cases). A postoperative histological analysis using the currently available methods revealed lymphoproliferative lesions; in this connection the patients continued treatment by oncologists. 

primary lymphomacentral nervous systemnoninvasive diagnosistotal removalprogressive neurological deficitпервичная лимфомацентральная нервная системанеинвазивная диагностикатотальное удалениенарастающий неврологический дефицит1. Никифоров А.С., Коновалов А.Н., Гусев Е.И. Клиническая неврология. М.: Медицина, 2004. Т. 3 (ч. 1), с. 400–402.Никифоров А.С., Коновалов А.Н., Гусев Е.И. Клиническая неврология. М.: Медицина, 2004. Т. 3 (ч. 1), с. 400–402.2. Власов П.В., Шейх Ж.В., Курзанцева О.O., Сидоров Ю.А. Лимфома центральной нервной системы. Радиология-практика 2004;1:26–30.Власов П.В., Шейх Ж.В., Курзанцева О.O., Сидоров Ю.А. Лимфома центральной нервной системы. Радиология-практика 2004;1:26–30.3. Muzitani T. Clinical aspects and pathogenesis of neurological complications due to malignant lymphomas. Rinsho Shinkeigaku 2002;42(11):1118–20.Muzitani T. Clinical aspects and pathogenesis of neurological complications due to malignant lymphomas. Rinsho Shinkeigaku 2002;42(11):1118–20.4. Hashizume Y., Yoshida M. Neuropathology of malignant lymphoma and its related disorders. Rinsho Shinkeigaku 2002;42(11):1121–3.Hashizume Y., Yoshida M. Neuropathology of malignant lymphoma and its related disorders. Rinsho Shinkeigaku 2002;42(11):1121–3.