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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">873</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2023-13-1-110-115</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Myeloid sarcoma of the larynx as manifestation of the terminal stage of myeloproliferative disease</article-title><trans-title-group xml:lang="ru"><trans-title>Миелоидная саркома гортани как манифестация терминальной стадии миелопролиферативного заболевания</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4822-392X</contrib-id><name-alternatives><name xml:lang="en"><surname>Kozhanov</surname><given-names>A. L.</given-names></name><name xml:lang="ru"><surname>Кожанов</surname><given-names>А. Л.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Andrey Leonidovich Kozhanov</p><p>17/1 Baumanskaya St., Moscow 105005</p></bio><bio xml:lang="ru"><p>Андрей Леонидович Кожанов</p><p>105005 Москва, ул. Бауманская, 17/1</p></bio><email>kojanov_a@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2591-0951</contrib-id><name-alternatives><name xml:lang="en"><surname>Kozhanov</surname><given-names>L. G.</given-names></name><name xml:lang="ru"><surname>Кожанов</surname><given-names>Л. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Department of Oncology and Radiation Therapy</p><p>17/1 Baumanskaya St., Moscow 1050051 Ostrovityanova St., Moscow 117997</p></bio><bio xml:lang="ru"><p>кафедра онкологии и лучевой терапии</p><p>105005 Москва, ул. Бауманская, 17/1117997 Москва, ул. Островитянова, 1</p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1082-8659</contrib-id><name-alternatives><name xml:lang="en"><surname>Kovrigina</surname><given-names>A. M.</given-names></name><name xml:lang="ru"><surname>Ковригина</surname><given-names>А. М.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>4a Novy Zykovsky proezd, 125167 Moscow</p></bio><bio xml:lang="ru"><p>125167 Москва, Новый Зыковский проезд, 4а</p></bio><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2411-5083</contrib-id><name-alternatives><name xml:lang="en"><surname>Chernotalova</surname><given-names>N. S.</given-names></name><name xml:lang="ru"><surname>Черноталова</surname><given-names>Н. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>17/1 Baumanskaya St., Moscow 105005</p></bio><bio xml:lang="ru"><p>105005 Москва, ул. Бауманская, 17/1</p></bio><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">City Clinical Oncological Hospital No. 1, Moscow Healthcare Department</institution></aff><aff><institution xml:lang="ru">ГБУЗ «Городская клиническая онкологическая больница №1 Департамента здравоохранения г. Москвы»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">N.I. Pirogov Russian National Research Medical University, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГАОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Hematology Research Center, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр гематологии» Минздрава России</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2023-06-02" publication-format="electronic"><day>02</day><month>06</month><year>2023</year></pub-date><volume>13</volume><issue>1</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>110</fpage><lpage>115</lpage><history><date date-type="received" iso-8601-date="2023-06-01"><day>01</day><month>06</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2023-06-01"><day>01</day><month>06</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Kozhanov A.L., Kozhanov L.G., Kovrigina A.M., Chernotalova N.S.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Кожанов А.Л., Кожанов Л.Г., Ковригина А.М., Черноталова Н.С.</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Kozhanov A.L., Kozhanov L.G., Kovrigina A.M., Chernotalova N.S.</copyright-holder><copyright-holder xml:lang="ru">Кожанов А.Л., Кожанов Л.Г., Ковригина А.М., Черноталова Н.С.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/873">https://ogsh.abvpress.ru/jour/article/view/873</self-uri><abstract xml:lang="en"><p>A rare clinical observation of advanced myeloid sarcoma developed through blast transformation of post-polycythemia vera myelofibrosis as extramedullary manifestation of acute myeloid leukemia affecting larynx, laryngopharynx, trachea, soft tissues of the neck, pleura, and skeletal bones is presented.</p></abstract><trans-abstract xml:lang="ru"><p>Описано редкое клиническое наблюдение распространенной миелоидной саркомы, возникшей в результате бластной трансформации постполицитемического миелофиброза как экстрамедуллярной манифестации острого миелоидного лейкоза с поражением гортани, гортаноглотки, трахеи, мягких тканей шеи, плевры и костей скелета.</p></trans-abstract><kwd-group xml:lang="en"><kwd>rare laryngeal tumors</kwd><kwd>myeloid sarcoma of the larynx</kwd><kwd>manifestation of acute myeloid leukemia</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>редкие опухоли гортани</kwd><kwd>миелоидная саркома гортани</kwd><kwd>манифестация острого миелоидного лейкоза</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Burns A. Observations of surgical anatomy, in Head and Neck. London: Royce, 1811. P. 364. Available at: https://pdfs. semanticscholar.org/9cc7/712605b042115331859c0b0e2a0e3691e 1f7.pdf?_ga=2.44749924.1191947278.1653293850- 735262139.1617541597.</mixed-citation><mixed-citation xml:lang="ru">Burns A. Observations of surgical anatomy, in Head and Neck. London: Royce, 1811. P. 364. Available at: https://pdfs.semanticscholar.org/9cc7/712605b042115331859c0b0e2a0e3691e1f7.pdf?_ga=2.44749924.1191947278.1653293850-735262139.1617541597.</mixed-citation></citation-alternatives></ref><ref id="B2"><label>2.</label><citation-alternatives><mixed-citation xml:lang="en">Кравцова Е.Н., Щетинина О.В. Миелоидная саркома в практике врача-оториноларинголога. Российская оториноларингология 2017;6:135–9. DOI: 10.18692/1810-4800-2017-6-135-139 Kravtsova E.N., Shchetinina O.V. Myeloid sarcoma in the practice of otorhinolaryngologist. Rossiiskaya otorinolaringologiya = Russian Otorhinolaryngology 2017;6:135–9 (In Russ.). DOI: 10.18692/1810-4800-2017-6-135-139</mixed-citation><mixed-citation xml:lang="ru">Кравцова Е.Н., Щетинина О.В. Миелоидная саркома в практике врача-оториноларинголога. Российская оториноларингология 2017;6:135–9. DOI: 10.18692/1810-4800-2017-6-135-139</mixed-citation></citation-alternatives></ref><ref id="B3"><label>3.</label><citation-alternatives><mixed-citation xml:lang="en">Климашевский В.Ф., Морозова Е.В., Шашкова Н.Г. и др. Миелоидная саркома шейки матки как проявление рецидива острого миелоидного лейкоза. Вопросы онкологии 2006;1:102–4. Klimashevskii V.F., Morozova E.V., Shashkova N.G. et al. Myeloid sarcoma of the uterine cervix as presentation of acute myeloid leukemia. Voprosy onkologii = Oncology Issues 2006;1:102–4 (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Климашевский В.Ф., Морозова Е.В., Шашкова Н.Г. и др. Миелоидная саркома шейки матки как проявление рецидива острого миелоидного лейкоза. Вопросы онкологии 2006;1:102–4.</mixed-citation></citation-alternatives></ref><ref id="B4"><label>4.</label><mixed-citation>Blair-Johnson M., Fiedler T., Fenna R. Human myeloperoxidase: structure of a cyanide complex and its interaction with bromide and thiocyanate substrates at 1.9: a resolution. Biochemistry 2001;40(46):13990–7. DOI: 10.1021/bi0111808</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Heerema-McKenney A., Arber D.A. Acute myeloid leukemia. Hematol Oncol Clin North Am 2009;23(4):633–54. DOI: 10.1016/j.hoc.2009.04.003</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Hoover A.C., Anderson C.M., Hoffman H.T. et al. Laryngeal chloroma heralding relapse of acute myeloid leukemia. J Clin Oncol 2014;32(7):e18–21. DOI: 10.1200/JCO.2012.47.0047</mixed-citation></ref><ref id="B7"><label>7.</label><citation-alternatives><mixed-citation xml:lang="en">Ковригина А.М. Пересмотренная классификация ВОЗ опухолей гемопоэтической и лимфоидной ткани, 2017 (4-е издание): миелоидные неоплазии. Архив патологии 2018;80(6):43–9. DOI: 10.17116/patol20188006143 Kovrigina A.M. A revised 4 edition WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues, 2017: myeloid neoplasms. Arkhiv Patologii = Pathology Archive 2018;80(6):43–9. (In Russ.). DOI: 10.17116/patol20188006143</mixed-citation><mixed-citation xml:lang="ru">Ковригина А.М. Пересмотренная классификация ВОЗ опухолей гемопоэтической и лимфоидной ткани, 2017 (4-е издание): миелоидные неоплазии. Архив патологии 2018;80(6):43–9. DOI: 10.17116/patol20188006143</mixed-citation></citation-alternatives></ref><ref id="B8"><label>8.</label><citation-alternatives><mixed-citation xml:lang="en">Arber D.A., Brunning R.D., Orazi A. et al. Acute myeloid leukemia, not otherwise specified. In: WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. 4th ed. Ed. by S.H. Swerdlow, E. Campo, N.L. Harris et al. Lyon: IARC Press, 2008. P. 130–139. Available at: https://www. cambridge.org/core/books/abs/diagnostic-bone-marrowhaematopathology/acute-myeloid-leukaemia/79CD7118FA51B89 BBFF85431858E10D1.</mixed-citation><mixed-citation xml:lang="ru">Arber D.A., Brunning R.D., Orazi A. et al. Acute myeloid leukemia, not otherwise specified. In: WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. 4th ed. Ed. by S.H. Swerdlow, E. Campo, N.L. Harris et al. Lyon: IARC Press, 2008. P. 130–139. Available at: https://www.cambridge.org/core/books/abs/diagnostic-bone-marrowhaematopathology/acute-myeloid-leukaemia/79CD7118FA51B89BBFF85431858E10D1.</mixed-citation></citation-alternatives></ref><ref id="B9"><label>9.</label><citation-alternatives><mixed-citation xml:lang="en">Кассирский И.А., Алексеев Г.А. Клиническая гематология. 4-е изд. М.: Медицина, 1970. 799 с. Kassirsky I.A., Alekseev G.A. Clinical hematology. 4th ed. Moscow: Medicine, 1970. 799 p.</mixed-citation><mixed-citation xml:lang="ru">Кассирский И.А., Алексеев Г.А. Клиническая гематология. 4-е изд. М.: Медицина, 1970. 799 с.</mixed-citation></citation-alternatives></ref><ref id="B10"><label>10.</label><mixed-citation>Aboutalebi A., Korman J.B., Sohani A.R. et al. Aleukemic cutaneous myeloid sarcoma. Jurn Cutan Pathol 2013;40(12): 996–1005. DOI: 10.1111/cup.12231</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Belknap A.R., Krause J.R. Myeloid sarcoma causing airway obstruction. Proc (Bayl Univ Med Cent) 2017;30(2):195–6. DOI: 10.1080/08998280.2017.11929583</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Dores G.M., Devesa S.S., Curtis R.E. et al. Acute leukemia incidence and patient survival among children and adults in the United States, 2001–2007. Blood 2012;119(1):34–43. DOI: 10.1182/blood-2011-04-347872</mixed-citation></ref><ref id="B13"><label>13.</label><citation-alternatives><mixed-citation xml:lang="en">Космос Д., Такач О., Адамеч З. и др. Описание случая лечения хлоромы облучением. Госпитальная медицина: наука и практика 2019;1(2):4–6. Kosmos D., Takach O., Adamech Z. et al. Case description treatment chloroma irradiation. Gospital’naya medicina: nauka i praktika = Hospital Medicine: Science and Practice 2019;1(2):4–6. (In Russ.).</mixed-citation><mixed-citation xml:lang="ru">Космос Д., Такач О., Адамеч З. и др. Описание случая лечения хлоромы облучением. Госпитальная медицина: наука и практика 2019;1(2):4–6.</mixed-citation></citation-alternatives></ref><ref id="B14"><label>14.</label><citation-alternatives><mixed-citation xml:lang="en">Horny H.P., Kaiserling E. Involvement of the larynx by hemopoietic neoplasms. An investigation of autopsy cases and review of the literature. Pathol Res Pract 1995;191(2):130–8. DOI: 10.1016/ S0344-0338(11)80562-5</mixed-citation><mixed-citation xml:lang="ru">Horny H.P., Kaiserling E. Involvement of the larynx by hemopoietic neoplasms. An investigation of autopsy cases and review of the literature. Pathol Res Pract 1995;191(2):130–8. DOI: 10.1016/S0344-0338(11)80562-5</mixed-citation></citation-alternatives></ref><ref id="B15"><label>15.</label><mixed-citation>Tan S.N., Gendeh H.S., Sani A., Mat-Baki M. Myeloid sarcoma: an unusual and rare laryngeal presentation. Int J Surg Case Rep 2016;21:99–103. DOI: 10.1016/j.ijscr. 2016.02.012</mixed-citation></ref></ref-list></back></article>
