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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">892</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2023-13-2-75-78</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЙ СЛУЧАЙ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Review of clinical cases of internal organ metastases into the skin of the head and neck</article-title><trans-title-group xml:lang="ru"><trans-title>Обзор клинических случаев метастазов опухолей внутренних органов в кожу области головы и шеи</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0119-2342</contrib-id><name-alternatives><name xml:lang="en"><surname>Kretova</surname><given-names>K. A.</given-names></name><name xml:lang="ru"><surname>Кретова</surname><given-names>К. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Kamilla Armanovna Kretova</p><p>1 Pirogova St., Novosibirsk 630090</p></bio><bio xml:lang="ru"><p>Камилла Армановна Кретова</p><p>630090 Новосибирск, ул. Пирогова, 1</p></bio><email>kamilla.armanovna@bk.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nazarko</surname><given-names>O. S.</given-names></name><name xml:lang="ru"><surname>Назарко</surname><given-names>О. С.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>1 Pirogova St., Novosibirsk 630090</p></bio><bio xml:lang="ru"><p>630090 Новосибирск, ул. Пирогова, 1</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0374-6057</contrib-id><name-alternatives><name xml:lang="en"><surname>Kopeikina</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Копейкина</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Bld. 5, 6 Zalessky St., Novosibirsk 630047</p></bio><bio xml:lang="ru"><p>630047 Новосибирск, ул. Залесского, 6, корп. 5</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Goncharova</surname><given-names>O. G.</given-names></name><name xml:lang="ru"><surname>Гончарова</surname><given-names>О. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Bld. 5, 6 Zalessky St., Novosibirsk 630047</p></bio><bio xml:lang="ru"><p>630047 Новосибирск, ул. Залесского, 6, корп. 5</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Obukhova</surname><given-names>D. A.</given-names></name><name xml:lang="ru"><surname>Обухова</surname><given-names>Д. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Bld. 5, 6 Zalessky St., Novosibirsk 630047</p></bio><bio xml:lang="ru"><p>630047 Новосибирск, ул. Залесского, 6, корп. 5</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Morozov</surname><given-names>D. V.</given-names></name><name xml:lang="ru"><surname>Морозов</surname><given-names>Д. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>Bld. 5, 6 Zalessky St., Novosibirsk 630047</p></bio><bio xml:lang="ru"><p>630047 Новосибирск, ул. Залесского, 6, корп. 5</p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1748-8957</contrib-id><name-alternatives><name xml:lang="en"><surname>Sergeeva</surname><given-names>S. V.</given-names></name><name xml:lang="ru"><surname>Сергеева</surname><given-names>И. Г.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>1 Pirogova St., Novosibirsk 630090</p></bio><bio xml:lang="ru"><p>630090 Новосибирск, ул. Пирогова, 1</p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6968-9596</contrib-id><name-alternatives><name xml:lang="en"><surname>Sidorov</surname><given-names>S. V.</given-names></name><name xml:lang="ru"><surname>Сидоров</surname><given-names>С. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>1 Pirogova St., Novosibirsk 630090</p><p>Bld. 5, 6 Zalessky St., Novosibirsk 630047</p></bio><bio xml:lang="ru"><p>630090 Новосибирск, ул. Пирогова</p><p>630047 Новосибирск, ул. Залесского, 6, корп. 5</p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0002-2537-5290</contrib-id><name-alternatives><name xml:lang="en"><surname>Shevchenko</surname><given-names>S. P.</given-names></name><name xml:lang="ru"><surname>Шевченко</surname><given-names>С. П.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>1 Pirogova St., Novosibirsk 630090</p><p>Bld. 5, 6 Zalessky St., Novosibirsk 630047</p></bio><bio xml:lang="ru"><p>630090 Новосибирск, ул. Пирогова</p><p>630047 Новосибирск, ул. Залесского, 6, корп. 5</p></bio><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Novosibirsk State University</institution></aff><aff><institution xml:lang="ru">ФГАОУ «Национальный исследовательский государственный университет»</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">City Clinical Hospital No. 1</institution></aff><aff><institution xml:lang="ru">ГБУЗ НО «Городская клиническая больница № 1»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2023-09-13" publication-format="electronic"><day>13</day><month>09</month><year>2023</year></pub-date><volume>13</volume><issue>2</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>75</fpage><lpage>78</lpage><history><date date-type="received" iso-8601-date="2023-09-13"><day>13</day><month>09</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2023-09-13"><day>13</day><month>09</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Kretova K.A., Nazarko O.S., Kopeikina E.V., Goncharova O.G., Obukhova D.A., Morozov D.V., Sergeeva S.V., Sidorov S.V., Shevchenko S.P.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Кретова К.А., Назарко О.С., Копейкина Е.В., Гончарова О.Г., Обухова Д.А., Морозов Д.В., Сергеева И.Г., Сидоров С.В., Шевченко С.П.</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Kretova K.A., Nazarko O.S., Kopeikina E.V., Goncharova O.G., Obukhova D.A., Morozov D.V., Sergeeva S.V., Sidorov S.V., Shevchenko S.P.</copyright-holder><copyright-holder xml:lang="ru">Кретова К.А., Назарко О.С., Копейкина Е.В., Гончарова О.Г., Обухова Д.А., Морозов Д.В., Сергеева И.Г., Сидоров С.В., Шевченко С.П.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/892">https://ogsh.abvpress.ru/jour/article/view/892</self-uri><abstract xml:lang="en"><p>Metastases of malignant tumors of the internal organs into the skin rarely occur, on average in 1–10 % of cases. They can be the first manifestation of malignant process in the absence of signs of the main disease or show progression of confirmed cancer. The article presents clinical cases of metastases of renal cell carcinoma and adenocarcinoma into the skin of the head and neck which currently is rare. Skin metastases are variable in their clinical manifestation. In the presented cases, resection of the lesions was required as symptomatic treatment.</p></abstract><trans-abstract xml:lang="ru"><p>Метастазы злокачественных новообразований внутренних органов в кожу встречаются довольно редко – в среднем в 1–10 % случаев. Они могут быть первым проявлением как злокачественного процесса, когда еще отсутствуют признаки основного заболевания, так и прогрессирования уже подтвержденного рака. В статье представлены клинические случаи метастазов почечно-клеточного рака и аденокарциномы в кожу области головы и шеи, что в настоящее время является редкостью. Кожные метастазы вариабельны в своем клиническом проявлении. В представленных случаях в качестве симптоматического лечения потребовалось иссечение новообразований.</p></trans-abstract><kwd-group xml:lang="en"><kwd>metastases in the skin of the head and neck</kwd><kwd>renal cell carcinoma metastases</kwd><kwd>adenocarcinoma metastases</kwd><kwd>metastasis</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>метастазы опухолей в кожу головы и шеи</kwd><kwd>метастазы почечно-клеточного рака</kwd><kwd>метастазы аденокарциномы</kwd><kwd>метастазирование</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Hu S.C.S., Chen G.-S., Wu C.-S. et al. Rates of cutaneous metastases from different internal malignancies: experience from a Taiwanese medical center. J Am Acad Dermatol 2009;60(3): 379–87. 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