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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="other" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Head and Neck Tumors</journal-id><journal-title-group><journal-title xml:lang="en">Head and Neck Tumors</journal-title><trans-title-group xml:lang="ru"><trans-title>Опухоли головы и шеи</trans-title></trans-title-group></journal-title-group><issn publication-format="print">2222-1468</issn><issn publication-format="electronic">2411-4634</issn><publisher><publisher-name xml:lang="en">Publishing House ABV Press</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">912</article-id><article-id pub-id-type="doi">10.17650/2222-1468-2023-13-3-32-42</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>DIAGNOSIS AND TREATMENT OF HEAD AND NECK TUMORS</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>ДИАГНОСТИКА И ЛЕЧЕНИЕ ОПУХОЛЕЙ ГОЛОВЫ И ШЕИ</subject></subj-group><subj-group subj-group-type="article-type"><subject></subject></subj-group></article-categories><title-group><article-title xml:lang="en">Quality of life of patients with tongue cancer after hemiglossectomy</article-title><trans-title-group xml:lang="ru"><trans-title>Качество жизни больных раком языка после гемиглоссэктомии</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4944-2507</contrib-id><name-alternatives><name xml:lang="en"><surname>Ganina</surname><given-names>Ch. A.</given-names></name><name xml:lang="ru"><surname>Ганина</surname><given-names>К. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><bold>Kristina A. Ganina </bold></p><p><italic>24 Kashirskoye Shosse, Moscow 115522</italic></p></bio><bio xml:lang="ru"><p><bold>Кристина Алексеевна Ганина </bold></p><p><italic>115522 Москва, Каширское шоссе, 24</italic></p><p> </p></bio><email>kristga@mail.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9132-3416</contrib-id><name-alternatives><name xml:lang="en"><surname>Kropotov</surname><given-names>M. A.</given-names></name><name xml:lang="ru"><surname>Кропотов</surname><given-names>М. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>24 Kashirskoye Shosse, Moscow 115522</italic></p></bio><bio xml:lang="ru"><p><italic>115522 Москва, Каширское шоссе, 24</italic></p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2283-1812</contrib-id><name-alternatives><name xml:lang="en"><surname>Saprina</surname><given-names>O. A.</given-names></name><name xml:lang="ru"><surname>Саприна</surname><given-names>О. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>24 Kashirskoye Shosse, Moscow 115522</italic></p></bio><bio xml:lang="ru"><p><italic>115522 Москва, Каширское шоссе, 24</italic></p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kosova</surname><given-names>E. V.</given-names></name><name xml:lang="ru"><surname>Косова</surname><given-names>Е. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>3 Ivankovskoe Shosse, Moscow 125367</italic></p></bio><bio xml:lang="ru"><p><italic>125367 Москва, Иваньковское шоссе, 3;</italic></p></bio><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2276-5755</contrib-id><name-alternatives><name xml:lang="en"><surname>Aketova</surname><given-names>T. A.</given-names></name><name xml:lang="ru"><surname>Акетова</surname><given-names>Т. А.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>24 Kashirskoye Shosse, Moscow 115522</italic></p></bio><bio xml:lang="ru"><p><italic>115522 Москва, Каширское шоссе, 24</italic></p></bio><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-7906-881X</contrib-id><name-alternatives><name xml:lang="en"><surname>Isaeva</surname><given-names>M. T.</given-names></name><name xml:lang="ru"><surname>Исаева</surname><given-names>М. Т.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>Bld. 1, 2/1 Barrikadnaya St., Moscow 125993</italic></p></bio><bio xml:lang="ru"><p><italic>125993 Москва, ул. Баррикадная, 2/1, стр. 1</italic></p></bio><xref ref-type="aff" rid="aff3"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-8861-7892</contrib-id><name-alternatives><name xml:lang="en"><surname>Gerasimov</surname><given-names>O. V.</given-names></name><name xml:lang="ru"><surname>Герасимов</surname><given-names>О. В.</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p><italic>18A Zagorodnoye Shosse, Moscow 117152</italic></p></bio><bio xml:lang="ru"><p><italic>117152 Москва, Загородное шоссе, 18А</italic></p></bio><xref ref-type="aff" rid="aff4"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">N.N. Blokhin National Medical Russian Research Center of Oncology, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБУ «Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">National Medical Research Center «Treatment and Rehabilitation Center», Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГАУ «Национальный медицинский исследовательский центр «Лечебно-реабилитационный центр» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff3"><aff><institution xml:lang="en">Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia</institution></aff><aff><institution xml:lang="ru">ФГБОУ ВПО «Российская медицинская академия непрерывного профессионального образования» Минздрава России</institution></aff></aff-alternatives><aff-alternatives id="aff4"><aff><institution xml:lang="en">City Oncological Hospital No. 1, Moscow Healthcare Department</institution></aff><aff><institution xml:lang="ru">ГБУЗ «Городская онкологическая больница № 1 Департамента здравоохранения г. Москвы»</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2023-12-12" publication-format="electronic"><day>12</day><month>12</month><year>2023</year></pub-date><volume>13</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>32</fpage><lpage>42</lpage><history><date date-type="received" iso-8601-date="2023-12-11"><day>11</day><month>12</month><year>2023</year></date><date date-type="accepted" iso-8601-date="2023-12-11"><day>11</day><month>12</month><year>2023</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2023, Ganina C.A., Kropotov M.A., Saprina O.A., Kosova E.V., Aketova T.A., Isaeva M.T., Gerasimov O.V.</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2023, Ганина К.А., Кропотов М.А., Саприна О.А., Косова Е.В., Акетова Т.А., Исаева М.Т., Герасимов О.В.</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="en">Ganina C.A., Kropotov M.A., Saprina O.A., Kosova E.V., Aketova T.A., Isaeva M.T., Gerasimov O.V.</copyright-holder><copyright-holder xml:lang="ru">Ганина К.А., Кропотов М.А., Саприна О.А., Косова Е.В., Акетова Т.А., Исаева М.Т., Герасимов О.В.</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://ogsh.abvpress.ru/jour/article/view/912">https://ogsh.abvpress.ru/jour/article/view/912</self-uri><abstract xml:lang="en"><p><bold>Introduction. </bold>The main part among all malignant neoplasms of the oral cavity is tongue cancer, the leading method of treatment of which is surgery. Surgical treatment leads to a violation of such important functions of the language as speech and swallowing, which in turn reduces the quality of life of patients. However, to date, opinions differ on the issue of performing language reconstruction. In addition, there are no clear indications for the use of one or another type of defect replacement, with the help of which it will be possible to achieve the best functional results.</p><p><bold>Aim.</bold><bold> </bold>To evaluate the functional results after hemiglossectomy for malignant neoplasms of the tongue, compare various reconstruction strategies (with and without a flap).</p><p><bold>Materials and methods. </bold>The study included 44 patients with tongue cancer with a follow-up period of at least 6 months. Functional results were assessed using a quality of life questionnaire and speech therapy assessment.</p><p><bold>Results. </bold>Patients who underwent tongue reconstruction had higher functional results and the best indicators of quality of life compared to patients who did not undergo reconstruction.</p><p><bold>Conclusion. </bold>Hemiglossectomy leads to impaired speech and swallowing functions and, accordingly, to a decrease in the quality of life. Since performing the reconstruction affects the functional results, it should be properly planned before the operation.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Введение. </bold>Основную часть всех злокачественных новообразований полости рта составляет рак языка, основным методом лечения которого является операция. хирургическое лечение приводит к нарушению таких важных функций, как речь и глотание, что снижает качество жизни пациентов. Однако на сегодняшний день единого мнения относительно целесообразности выполнения реконструкции языка нет. К тому же не существует четких показаний для использования того или иного вида замещения дефекта, с помощью которого можно достичь наилучших функциональных результатов.</p><p><bold>Цель исследования </bold>– оценить функциональные результаты после гемиглоссэктомии по поводу злокачественных новообразований языка, сравнить различные стратегии реконструкции (с использованием лоскута и без него).</p><p><bold>Материалы и методы. </bold>В исследование включены 44 пациента с раком языка с периодом наблюдения не менее 6 мес. функциональные результаты проанализированы с помощью опросника качества жизни и логопедической оценки.</p><p><bold>Результаты. </bold>пациенты, которым выполнялась реконструкция языка, имели более высокие функциональные результаты и лучшие показатели качества жизни по сравнению с пациентами, которым она не проводилась.</p><p><bold>Заключение. </bold>Выполнение гемиглоссэктомии приводит к нарушению функций речи и глотания и, соответственно, к снижению качества жизни. поскольку выполнение реконструкции влияет на функциональные результаты, она должна быть надлежащим образом спланирована перед операцией.</p></trans-abstract><kwd-group xml:lang="en"><kwd>language cancer</kwd><kwd>quality of life</kwd><kwd>functional results</kwd><kwd>language reconstruction</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак языка</kwd><kwd>качество жизни</kwd><kwd>функциональные результаты</kwd><kwd>реконструкция языка</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Tagliabue M., Belloni P., De Berardinis R. et al. A systematic review and meta-analysis of the prognostic role of age in oral tongue cancer. Cancer Med 2021;10(8):2566–78. DOI: 10.1002/cam4.3795</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Jahanbani J., Ghotbi M., Shahsavari F. et al. Selective anticancer activity of superparamagnetic iron oxide nanoparticles (SPIONs) against oral tongue cancer using in vitro methods: the key role of oxidative stress on cancerous mitochondria. J Biochem Mol Toxicol 2020;34(10):e22557. DOI: 10.1002/jbt.22557</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Bakshi J., Goyal A.K., Saini J. Quality of life in oral cancer patients following surgical excision and flap reconstruction. J Maxillofac Oral Surg 2022;21(2):316–31. DOI: 10.1007/s12663-020-01499-5</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Gabriele M., Michael G., Giulia M. et al. Quality of life, swallowing and speech outcomes after oncological treatment for mobile tongue carcinoma. Eur J Plast Surg 2020;43:247–56. DOI: 10.1007/s00238-019-01593-z</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Yi C.R., Jeong W.S., Oh T.S. et al. Analysis of speech and functional outcomes in tongue reconstruction after hemiglossectomy. J Reconstr Microsurg 2020;36(7):507–13. DOI: 10.1055/s-0040-1709493</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Chang E.I., Yu P., Skoracki R.J. et al. Comprehensive analysis of functional outcomes and survival after microvascular reconstruction of glossectomy defects. Ann Surg Oncol 2015;22(9):3061–9. DOI: 10.1245/s10434-015-4386-6</mixed-citation></ref><ref id="B7"><label>7.</label><mixed-citation>Bressmann T., Sader R., Whitehill T.L., Samman N. Consonant intelligibility and tongue motility in patients with partial glossectomy. J Oral Maxillofac Surg 2004;62(3):298–303. DOI: 10.1016/j.joms.2003.04.017</mixed-citation></ref><ref id="B8"><label>8.</label><mixed-citation>Li X., Sun Q., Guo S. Functional assessment in patients undergoing radial forearm flap following hemiglossectomy. J Craniofacial Surg 2016;27(2):e172–5. DOI: 10.1097/SCS.0000000000002261</mixed-citation></ref><ref id="B9"><label>9.</label><mixed-citation>Takatsu J., Hanai N., Suzuki H. et al. Phonologic and acoustic analysis of speech following glossectomy and the effect of rehabilitation on speech outcomes. J Oral Maxillofac Surg 2017;75(7):1530–41. DOI: 10.1016/j.joms.2016.12.004</mixed-citation></ref><ref id="B10"><label>10.</label><mixed-citation>Mannelli G., Arcuri F., Agostini T. et al. Classification of tongue cancer resection and treatment algorithm. J Surg Oncol 2018;117(5):1092–9. DOI: 10.1002/jso.24991</mixed-citation></ref><ref id="B11"><label>11.</label><mixed-citation>Kansy K., Mueller A.A., Mücke T. et al. A worldwide comparison of the management of surgical treatment of advanced oral cancer. J Craniomaxillof Surg 2018;46(3):511–20. DOI: 10.1016/j.jcms.2017.12.031</mixed-citation></ref><ref id="B12"><label>12.</label><mixed-citation>Hsiao H.T., Leu Y.S., Lin C.C. Primary closure versus radial forearm flap reconstruction after hemiglossectomy: functional assessment of swallowing and speech. Ann Plast Surg 2002;49(6):612–6. DOI: 10.1097/00000637-200212000-00010</mixed-citation></ref><ref id="B13"><label>13.</label><mixed-citation>Chuanjun C., Zhiyuan Z., Shaopu G. et al. Speech after partial glossectomy: a comparison between reconstruction and nonreconstruction patients. J Oral Maxillofac Surg 2002;60(4):404–7. DOI: 10.1053/joms.2002.31228</mixed-citation></ref><ref id="B14"><label>14.</label><mixed-citation>Ji J.B., Cho Y.H., Song C.M. et al. Long-term functional outcomes after resection of tongue cancer: determining the optimal reconstruction method. Eur Arch Otorhinolaryngol 2017;274(10):3751–6. DOI: 10.1007/s00405-017-4683-8</mixed-citation></ref><ref id="B15"><label>15.</label><mixed-citation>Riva G., Sapino S., Ravera M. et al. Long-term functional outcomes and quality of life after partial glossectomy for T2 squamous cell carcinomas. Braz J Otorhinolaryngol 2022;4(Supple 4):S33–43. DOI: 10.1016/j.bjorl.2021.06.009</mixed-citation></ref><ref id="B16"><label>16.</label><mixed-citation>Lee D.Y., Ryu Y.J., Hah J.H. et al. Long-term subjective tongue function after partial glossectomy. J Oral Rehabil 2014;41(10):754–8. DOI: 10.1111/joor.12193</mixed-citation></ref><ref id="B17"><label>17.</label><mixed-citation>Shin Y.S., Kob Y.W., Kim S.H. et al. Radio-therapy deteriorates postoperative functional outcome after partial glossectomy with free flap reconstruction. J Oral Maxillofac Surg 2012;70(1):216–20. DOI: 10.1016/j.joms.2011.04.014</mixed-citation></ref><ref id="B18"><label>18.</label><mixed-citation>Furia C.L., Kowalski L.P., Latorre M.R. et al. Speech intelligibility after glossectomy and speech rehabilitation. Arch Otolaryngol Head Neck Surg 2001;127(7):877–83.</mixed-citation></ref><ref id="B19"><label>19.</label><mixed-citation>Dziegielewski P.T., Ho M.L., Rieger J. et al. Total glossectomy with laryngeal preservation and free flap reconstruction: objective functional outcomes and systematic review of the literature. Laryngoscope 2013;123(1):140–5. DOI: 10.1002/lary.23505</mixed-citation></ref></ref-list></back></article>
