Solitary metastasis of the clear cell variant of renal cell carcinoma into the thyroid gland
- Authors: Sevrukov F.E.1, Isaev P.A.1, Medvedev V.S.1, Ilyin A.A.1, Polkin V.V.1, Panaseikin Y.A.1, Derbugov D.N.1, Zhavoronkova E.V.1, Ivanov S.A.1, Kaprin A.D.2
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Affiliations:
- A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
- National Medical Research Radiological Center, Ministry of Health of Russia
- Issue: Vol 9, No 3 (2019)
- Pages: 77-82
- Section: CASE REPORT
- Published: 31.10.2019
- URL: https://ogsh.abvpress.ru/jour/article/view/425
- DOI: https://doi.org/10.17650/2222-1468-2019-9-3-77-82
- ID: 425
Cite item
Full Text
Abstract
Clinical case of solitary metastasis of the clear cell variant of renal cell carcinoma into the thyroid gland was analyzed. The thyroid mass was initially considered to be benign. The diagnostic showed signs similar to thyroid follicular neoplasia. The patient was operated on. The thyroid tumor was finally diagnosed as metastasis from clear cell variant of renal cell carcinoma.
About the authors
F. E. Sevrukov
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Email: fake@neicon.ru
ORCID iD: 0000-0002-9756-6275
10 Marshala Zhukova St., 249031 Obninsk
Russian FederationP. A. Isaev
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Author for correspondence.
Email: isaev@mrrc.obninsk.ru
ORCID iD: 0000-0003-1583-0106
10 Marshala Zhukova St., 249031 Obninsk Russian Federation
V. S. Medvedev
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Email: fake@neicon.ru
10 Marshala Zhukova St., 249031 Obninsk Russian Federation
A. A. Ilyin
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Email: fake@neicon.ru
ORCID iD: 0000-0002-6581-633X
10 Marshala Zhukova St., 249031 Obninsk Russian Federation
V. V. Polkin
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Email: fake@neicon.ru
ORCID iD: 0000-0003-0857-321X
10 Marshala Zhukova St., 249031 Obninsk Russian Federation
Yu. A. Panaseikin
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Email: fake@neicon.ru
10 Marshala Zhukova St., 249031 Obninsk Russian Federation
D. N. Derbugov
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Email: fake@neicon.ru
10 Marshala Zhukova St., 249031 Obninsk Russian Federation
E. V. Zhavoronkova
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Email: fake@neicon.ru
10 Marshala Zhukova St., 249031 Obninsk Russian Federation
S. A. Ivanov
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center, Ministry of Health of Russia
Email: fake@neicon.ru
ORCID iD: 0000-0001-7689-6032
10 Marshala Zhukova St., 249031 Obninsk Russian Federation
A. D. Kaprin
National Medical Research Radiological Center, Ministry of Health of Russia
Email: fake@neicon.ru
3 2nd Botkinsky Proezd, Moscow 125284
Russian FederationReferences
- Chung A.Y., Tran T.B., Brumund K.T. et al. Metastases to the thyroid: a review of the literature from the last decade. Thyroid 2012;22(3):258–68. doi: 10.1089/thy.2010.0154.
- Kriger A.G., Paklina O.V., Kochatkov A.V. et al. The metastatic invasion of pancreas by renal cancer. Khirurgiya. Zhurnal im. N.I. Pirogova = Pirogov Russian Journal of Surgery 2012;(9):26–31. (In Russ.)
- Leva J. Zur Lehre qes Morbus Addissonii. Arch Part Anat 1891;125(1):35–74.
- Pinsky S.B., Kalinin A.P., Beloborodov V.A., Dvornichenko V.V. Rare tumors and diseases of the thyroid gland. Irkutsk, 1999. 208 p. (In Russ.)
- Bianchi M., Sun M., Jeldres C. et al. Distribution of metastatic sites in renal cell carcinoma: a population-based analysis. Ann Oncol 2012;23(4):973–80. doi: 10.1093/annonc/mdr362.
- Kobayashi K., Hirokawa M., Yabuta T. et al. Metastatic carcinoma to the thyroid gland from renal cell carcinoma: role of ultrasonography in preoperative diagnosis. Thyroid Res 2015;8:4. doi: 10.1186/s13044-015-0016-4.
- Song O., Koo J.S., Kwak J.Y. et al. Metastatic renal cell carcinoma in the thyroid gland: ultrasonographic features and the diagnostic role of core needle biopsy. Ultrasonography 2017;36(3):252–9. doi: 10.14366/usg.16037.
- Rizzo M., Rossi R.T., Bonaffini O. et al. Thyroid metastasis of clear cell renal carcinoma: report of a case. Diagn Cytopathol 2009;37(10):759–62. doi: 10.1002/dc.21117.
- Iesalnieks I., Machens A., Bures C. et al. Local recurrence in the neck and survival after thyroidectomy for metastatic renal cell carcinoma. Ann Surg Oncol 2015;22(6):1798–805. doi: 10.1245/s10434-014-4266-5.
- Motzer R.J., Bacik J., Schwartz L.H. et al. Prognostic factors for survival in previously treated patients with metastatic renal cell carcinoma. J Clin Oncol 2004;22(3):454–63. doi: 10.1200/JCO.2004.06.132.
- Vogl U., Zehetgruber H., Dominkus M. et al. Prognostic factors in metastatic renal cell carcinoma: metastasectomy as independent prognostic variable. Br J Cancer 2006;95(6):691–8. doi: 10.1038/sj.bjc.6603327.
- Gravis G., Chanez B., Derosa L. et al. Effect of glandular metastases on overall survival of patients with metastatic clear cell renal cell carcinoma in the antiangiogenic therapy era. Urol Oncol 2016;34(4):167.e17–23. doi: 10.1016/j.urolonc.2015.10.015.
- Bedke J., Gauler T., Grünwald V. et al. Systemic therapy in metastatic renal cell carcinoma. World J Urol 2017;35(2):179–88. doi: 10.1007/s00345-016-1868-5.
- Thomas A.Z., Adibi M., Borregales L.D. et al. Cytoreductive surgery in the era of targeted molecular therapy. Transl Androl Urol 2015;4(3):301–9. doi: 10.3978/j.issn.2223-4683.2015.04.09.
- Abel E.J., Wood C.G. Cytoreductive nephrectomy for metastatic RCC in the era of targeted therapy. Nat Rev Urol 2009;6(7):375–83. doi: 10.1038/nrurol.2009.102.
- Dabestani S., Marconi L., Hofmann F. еt al. Local treatments for metastases of renal cell carcinoma: a systematic review. Lancet Oncol 2014;15(12):e549–61. doi: 10.1016/S1470-2045(14)70235-9.
- Weiti H., Chevalley J. Coitres jaune safran. Metastases dans la thyroide des hypernefromes. Pres Med 1966;74(50):2595–8.
- Horowitz J.J., Fajardo M., Callahan L.D., Yang R. Clear cell carcinoma of the thyroid. Int Surg 1966;45(4):429–39.
- Yamauchi M., Kai K., Shibamiya N. et al. Didactic surgical experience of thyroid metastasis from renal cell carcinoma: a case report. World J Clin Cases 2018;6(15):1018–23. doi: 10.12998/wjcc.v6.i15.1018.
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