Clinical experience of combined organ-preserving treatment of laryngopharyngeal cancer with spread to the cervical esophagus

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Abstract

Introduction. Laryngopharyngeal cancer accounts for about half of the total number of malignant neoplasms of ENT organs. Despite the availability of examination, in most patients tumors of this localization are detected at late stages, and the long-term results of treatment of locally advanced cancer of the larynx remain unsatisfactory.

Clinical case. This article presents two clinical cases of combined organ-preserving treatment of laryngopharyngeal cancer with spread to the cervical esophagus. At the first stage, patients underwent organ-preserving surgical treatment with a reconstructive plastic component according to the methodology developed at the A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology. Then a postoperative course of chemoradiotherapy was carried out.

Conclusion. The use of combined organ-preserving techniques using displaced skin-muscle flaps in the treatment of locally advanced laryngopharyngeal cancer involving the cervical esophagus allows in some cases to avoid crippling surgery, preserve the larynx and achieve satisfactory functional results, which significantly improves the quality of life of patients.

About the authors

V. A. Rozhnov

A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology, Ministry of Health of Russia

Author for correspondence.
Email: vit@mrrc.obninsk.ru
ORCID iD: 0000-0003-4966-1187

Vitaly A. Rozhnov 

10 Marshal Zhukov St., Obninsk 249031

Russian Federation

P. I. Spirin

A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology, Ministry of Health of Russia

Email: fake@neicon.ru
ORCID iD: 0000-0002-6919-9041

10 Marshal Zhukov St., Obninsk 249031

Russian Federation

V. V. Polkin

A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology, Ministry of Health of Russia

Email: fake@neicon.ru
ORCID iD: 0000-0003-0857-321X

10 Marshal Zhukov St., Obninsk 249031

Russian Federation

I. А. Gulidov

A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology, Ministry of Health of Russia

Email: fake@neicon.ru

10 Marshal Zhukov St., Obninsk 249031

Russian Federation

A. V. Dem’yanovich

A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology, Ministry of Health of Russia

Email: fake@neicon.ru

10 Marshal Zhukov St., Obninsk 249031

Russian Federation

A. D. Kaprin

National Medical Research Center of Radiology, Ministry of Health of Russia;
Medical Institute, Peoples’ Friendship University of Russia

Email: fake@neicon.ru
ORCID iD: 0000-0002-3071-3971

4 Koroleva St., Obninsk 249036, Russia ,

6 Miklukho-Maklaya St., Moscow 117198

Russian Federation

S. A. Ivanov

A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Center of Radiology, Ministry of Health of Russia

Email: fake@neicon.ru
ORCID iD: 0000-0001-7689-6032

10 Marshal Zhukov St., Obninsk 249031

Russian Federation

References

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  8. Majidov M.G. A new approach to chemoradiotherapy of patients with locally advanced laryngopharyngeal cancer. Vestnik RONC im. N.N. Blohina RAMN. = Bulletin of the N.N. Blokhin Russian Research Center of the Russian Academy of Medical Sciences 2006;17(1):18–9. (In Russ.).
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