Guidelines for radioiodine therapy in differentiated thyroid cancer and post-therapeutic follow-up

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Abstract

The radioiodine therapy is a one of the basic elements at combined treatment of differentiated thyroid cancer and is an alternative method for patients with distant metastases and a potentially high risk of tumor recurrence. It has been used in clinical practice for more than 80 years. The first report on the phenomenon of accumulation of 130I/131I in a metastatic focus of differentiated thyroid cancer was published by A. Keston et al. in 1942, and in 1946, the production of 131I was established, and the drug became available. In our country, radioiodine therapy has been widely used for the treatment of differentiated thyroid cancer since 1982.

This article presents methodological recommendations for radioiodine therapy of patients with differentiated thyroid cancer, provides a modern examination algorithm, discusses the basic principles of laboratory, instrumental diagnostics and treatment approaches treatment of this disease.

About the authors

A. Yu. Shurinov

A.F. Tsyb Medical Radiological Research Center — branch of the National Medical Research Center of Radiology, Ministry of Health of Russia

Author for correspondence.
Email: shurinov@mail.ru
ORCID iD: 0000-0003-4934-2012

Andrey Yu. Shurinov.

4 Koroleva St., Obninsk 249036

Russian Federation

E. V. Borodavina

A.F. Tsyb Medical Radiological Research Center — branch of the National Medical Research Center of Radiology, Ministry of Health of Russia

Email: smysmymrik2007@yandex.ru
ORCID iD: 0000-0002-3306-5906

Ekaterina V. Borodavina.

4 Koroleva St., Obninsk 249036

Russian Federation

V. V. Krylov

A.F. Tsyb Medical Radiological Research Center — branch of the National Medical Research Center of Radiology, Ministry of Health of Russia

Email: fake@neicon.ru

4 Koroleva St., Obninsk 249036

Russian Federation

M. A. Sigov

A.F. Tsyb Medical Radiological Research Center — branch of the National Medical Research Center of Radiology, Ministry of Health of Russia

Email: fake@neicon.ru
ORCID iD: 0000-0003-0985-1234

4 Koroleva St., Obninsk 249036

Russian Federation

A. A. Rodichev

A.F. Tsyb Medical Radiological Research Center — branch of the National Medical Research Center of Radiology, Ministry of Health of Russia

Email: fake@neicon.ru
ORCID iD: 0000-0002-2623-3975

4 Koroleva St., Obninsk 249036

Russian Federation

S. A. Ivanov

A.F. Tsyb Medical Radiological Research Center — branch of the National Medical Research Center of Radiology, Ministry of Health of Russia; Peoples’ Friendship University of Russia

Email: fake@neicon.ru
ORCID iD: 0000-0001-7689-6032

4 Koroleva St., Obninsk 249036; 6 Miklukho-Maklaya St., Moscow 117198

Russian Federation

A. D. Kaprin

Peoples’ Friendship University of Russia; National Medical Research Radiological Center, Ministry of Health of Russia; P.A. Herzen Moscow Oncology Research Institute — a branch of the National Medical Radiology Research Center, Ministry of Health of Russia

Email: fake@neicon.ru
ORCID iD: 0000-0001-8784-8415

6 Miklukho-Maklaya St., Moscow 117198; 4 Koroleva St., Obninsk 249036; 3 2nd Botkinsky Proezd, Moscow 125284

Russian Federation

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