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Neoadjuvant target therapy of differentiated thyroid cancer (clinical observation)
- Authors: Isaev P.A.1, Vasilkov S.V.1, Pimonova I.S.1, Sevrukov F.E.1, Polkin V.V.1, Syomin D.Y.1, Ilyin A.A.1, Medvedev V.S.1, Silantyeva N.K.1, Agababyan T.A.1
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Affiliations:
- A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
- Issue: Vol 7, No 1 (2017)
- Pages: 86-90
- Section: CASE REPORT
- Published: 02.04.2017
- URL: https://ogsh.abvpress.ru/jour/article/view/242
- DOI: https://doi.org/10.17650/2222-1468-2017-7-1-86-90
- ID: 242
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Abstract
In the article a case of non-resectable differentiated thyroid cancer (DTC) is described. A recurrent thyroid tumor deforms the oropharyngeal lumen and laryngeal vestibule and bears down on the left esophageal wall and trachea. The authors present literature data on Nexavar target therapy and focus on the fact that no cases of combination treatment with target therapy and surgery of non-resectable progressive DTC were described until now. In view of this, this clinical report is unique and dictates a need to determine new Nexavar (Sorafenib) indications for use in a neoadjuvant regimen.
About the authors
P. A. Isaev
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Author for correspondence.
Email: isaev@mrrc.obninsk.ru
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia Russian Federation
S. V. Vasilkov
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Email: fake@neicon.ru
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia Russian Federation
I. S. Pimonova
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Email: fake@neicon.ru
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia Russian Federation
F. E. Sevrukov
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Email: fake@neicon.ru
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia Russian Federation
V. V. Polkin
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Email: fake@neicon.ru
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia Russian Federation
D. Yu. Syomin
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Email: fake@neicon.ru
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia Russian Federation
A. A. Ilyin
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Email: fake@neicon.ru
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia Russian Federation
V. S. Medvedev
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Email: fake@neicon.ru
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia Russian Federation
N. K. Silantyeva
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Email: fake@neicon.ru
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia Russian Federation
T. A. Agababyan
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Email: fake@neicon.ru
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia Russian Federation
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