EXPERIENCE OF USING ALLOGENIC BIOIMPLANTS IN LARYNGEAL RESECTION

E. N. Novozhilova; Новожилова Е. Н.; A. P. Fedotov; Федотов А. П.; I. F. Chumakov; Чумаков И. Ф.; L. T. Volova; Волова Л. Т.; O. V. Olshanskaya; Ольшанская О. В.; E. G. Akhtyrskaya; Ахтырская Е. Г.; T. A. Kochetkova; Кочеткова Т.; A. Kakorin; Какорин А. С.

doi:10.17650/2222-1468-2017-7-2-60-64

EXPERIENCE OF USING ALLOGENIC BIOIMPLANTS IN LARYNGEAL RESECTION

Authors: Novozhilova E.N.¹, Fedotov A.P.¹, Chumakov I.F.¹, Volova L.T.², Olshanskaya O.V.³, Akhtyrskaya E.G.¹, Kochetkova T.A.¹, Kakorin A.¹
Affiliations:
1. Moscow City Oncological Hospital No. 62 of the Moscow Healthcare Department
2. Samara Tissue Bank of the Research Institute of Experimental Medicine and Biotechnology of the Samara State Medical University, Ministry of Health of Russia
3. I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Issue: Vol 7, No 2 (2017)
Pages: 60-64
Section: ORIGINAL REPORTS
Published: 27.06.2017
URL: https://ogsh.abvpress.ru/jour/article/view/266
DOI: https://doi.org/10.17650/2222-1468-2017-7-2-60-64
ID: 266

Cite item

Full Text

Abstract
About the authors
References
Supplementary files
Statistics

Abstract

Introduction. Currently, a great importance is being attached to improvement of the surgical component of combination treatment of locally advanced laryngeal cancer. New technological capabilities (transoral microsurgery of the larynx and robotic surgery) offer great opportunities for early cancer stages. However, in some cases capabilities of endoscopic laser intervention are limited. Therefore, open laryngeal resection is still relevant as it serves as the only type of radical organ preservation treatment for stages Т2–Т3. But major laryngeal resection is associated with a problem of tissue defect closure.

The article describes data on the use of biocompatible materials, their advantages and disadvantages. The study objective is to present experience of using a Russian allogenic bioimplant for plastic reconstruction of the opening of the larynx after laryngeal resection.

Materials and methods. The authors present their experience of using a Russian bioimplant produced in collaboration with the Samara Tissue Bank of the Research Institute of Experimental Medicine and Biotechnology of the Samara State Medical University. The material was tested in anterolateral laryngeal resection with simultaneous reconstruction in 5 patients with stages Т2–Т3 laryngeal cancer and in a patient with chondrosarcoma.

Conclusion. The Russian biocompatible implant served as a reliable, simple, cheap, and effective variant of plastic material for reconstruction of the larynx.

Keywords

laryngeal cancer, laryngeal resection, plastic surgery, allotransplant, autotransplants, biomaterials

About the authors

E. N. Novozhilova

Moscow City Oncological Hospital No. 62 of the Moscow Healthcare Department

Author for correspondence.
Email: novozhilova@yandex.ru

27–3 Istra, Krasnogorsk District, Moscow Region 143423

Russian Federation

A. P. Fedotov

Moscow City Oncological Hospital No. 62 of the Moscow Healthcare Department

Email: fake@neicon.ru

27–3 Istra, Krasnogorsk District, Moscow Region 143423

Russian Federation

I. F. Chumakov

Moscow City Oncological Hospital No. 62 of the Moscow Healthcare Department

Email: fake@neicon.ru

27–3 Istra, Krasnogorsk District, Moscow Region 143423

Russian Federation

L. T. Volova

Samara Tissue Bank of the Research Institute of Experimental Medicine and Biotechnology of the Samara State Medical University, Ministry of Health of Russia

Email: fake@neicon.ru

20 Gagarin St., Samara

Russian Federation