Follicular dendritic cell sarcoma: a report of cases and a literature review

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Abstract

The article is devoted to the diagnosis and treatment of an extremely rare tumor – a sarcoma from follicular dendritic cells with extranodal lesion in the region of the head and neck. These tumors are characterized by a high potential for metastasis and recurrence. Difficulties in choosing the optimal treatment tactics are associated with a small number of observations. Surgical, radiotherapeutics and chemotherapy methods are used. The literature data and the description of 2 own clinical observations of the sarcoma from follicular dendritic cells (with the involvement of the maxillary sinus and the nasal cavity) are presented. Treatment (surgery followed by radiotherapy) was successful. The appointment of adjuvant therapy improves the results of treatment in comparison with the surgical method alone.

About the authors

S. B. Alieva

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.

Author for correspondence.
Email: drsevil@mail.ru
ORCID iD: 0000-0002-6835-5567

24 Kashirskoe Shosse, Moscow 115478.

Russian Federation

I. A. Zaderenko

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.

Email: fake@neicon.ru
ORCID iD: 0000-0003-0183-4827
24 Kashirskoe Shosse, Moscow 115478. Russian Federation

A. M. Mudunov

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.

Email: fake@neicon.ru
ORCID iD: 0000-0002-0918-3857
24 Kashirskoe Shosse, Moscow 115478. Russian Federation

A. V. Nazarenko

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.

Email: fake@neicon.ru
ORCID iD: 0000-0003-1273-2017
24 Kashirskoe Shosse, Moscow 115478. Russian Federation

V. V. Mochal’nikova

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.

Email: fake@neicon.ru
24 Kashirskoe Shosse, Moscow 115478. Russian Federation

O. N. Karp

Unim.

Email: fake@neicon.ru
ORCID iD: 0000-0002-7390-871X
Build. 1, 42 Bol’shoy Bulvar, Skolkovo Innovation Center, Moscow 121205. Russian Federation

R. I. Azizyan

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.

Email: fake@neicon.ru
ORCID iD: 0000-0002-4046-1894
24 Kashirskoe Shosse, Moscow 115478. Russian Federation

A. A. Akhundov

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.

Email: fake@neicon.ru
ORCID iD: 0000-0002-9543-990X
24 Kashirskoe Shosse, Moscow 115478. Russian Federation

V. Т. Aslanukov

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.

Email: fake@neicon.ru
ORCID iD: 0000-0001-6590-9889
24 Kashirskoe Shosse, Moscow 115478. Russian Federation

O. P. Trofimova

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.

Email: fake@neicon.ru
24 Kashirskoe Shosse, Moscow 115478. Russian Federation

A. V. Khromushina

Department of Maxillo-Facial Surgery and Operative Dentistry, RUDN University.

Email: fake@neicon.ru
ORCID iD: 0000-0003-1673-7261
Miklukho-Maklaya St., Moscow 117198. Russian Federation

A. E. Каzimov

N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.

Email: fake@neicon.ru
ORCID iD: 0000-0002-7117-9453
24 Kashirskoe Shosse, Moscow 115478. Russian Federation

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