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Possibilities of magnetic resonance imaging in SWI mode in differential diagnosis of brain gliomas (G3–G4) and primary lymphomas
- Authors: Sashin D.V.1, Dolgushin M.B.1, Kobyakova E.A.1, Bekyashev A.K.1, Subbotin A.S.1, Nechipay E.A.1, Romanov D.S.1, Kozlov N.A.1
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Affiliations:
- N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
- Issue: Vol 10, No 2 (2020)
- Pages: 38-45
- Section: ORIGINAL REPORT
- Published: 24.07.2020
- URL: https://ogsh.abvpress.ru/jour/article/view/525
- DOI: https://doi.org/10.17650/2222-1468-2020-10-2-38-45
- ID: 525
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Abstract
The study objective is to assess the possibilities of magnetic resonance imaging (MRI) in SWI (susceptibility weighted imaging) in the differential diagnosis of glial brain tumors and primary brain lymphomas.
Materials and methods. Fifty-four patients with brain tumors were studied (men – 27 (50 %), women – 27 (50 %)). Average age 57.9 years. Histological examination of the surgical material revealed the glial nature of tumors in 41 patients (26 of them with glioblastoma, anaplastic astrocytomas – 15), primary brain lymphomas – in 13 patients. Brain MRI was performed using tomographs with a magnetic field of 3 and 1.5 T. A semi-quantitative assessment of the data obtained in the SWI mode based on the classification of ITSS (intratumoral susceptibility signals), reflecting the severity of interstitial vascular architectonics and microbleeding.
Results. The degree of ITSS was 3 in glioblastomas (G4 ) in 26 (100 %) cases, in the structure of gliomas (G3 ) the ITSS values were 3 in 3 (20 %) cases, in the remaining 12 (80 %) cases – ITSS 2. In the group of primary brain lymphomas, the ITSS 1 was in 4 (30.7 %) cases, ITSS 0 was in 9 (69.3 %) cases.
Conclusion. MRI in SWI mode is a promising technique that allows one to quantify the degree of pathological changes in tumor vascular architectonics and intratumoral hemorrhages and has shown high specificity in the differential diagnosis of malignant gliomas and lymphomas of the brain, accompanied by active accumulation of contrast medium.
About the authors
D. V. Sashin
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Author for correspondence.
Email: denchegs70@gmail.com
ORCID iD: 0000-0003-0431-2610
24 Kashirskoe Shosse, Moscow 115478 Russian Federation
M. B. Dolgushin
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Email: fake@neicon.ru
ORCID iD: 0000-0003-3930-5998
24 Kashirskoe Shosse, Moscow 115478 Russian Federation
E. A. Kobyakova
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Email: fake@neicon.ru
ORCID iD: 0000-0001-8347-1243
24 Kashirskoe Shosse, Moscow 115478 Russian Federation
A. Kh. Bekyashev
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Email: fake@neicon.ru
ORCID iD: 0000-0002-4160-9598
24 Kashirskoe Shosse, Moscow 115478 Russian Federation
A. S. Subbotin
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Email: fake@neicon.ru
ORCID iD: 0000-0002-4648-2362
24 Kashirskoe Shosse, Moscow 115478 Russian Federation
E. A. Nechipay
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Email: fake@neicon.ru
ORCID iD: 0000-0002-3785-7070
24 Kashirskoe Shosse, Moscow 115478 Russian Federation
D. S. Romanov
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Email: fake@neicon.ru
ORCID iD: 0000-0003-3942-4102
24 Kashirskoe Shosse, Moscow 115478 Russian Federation
N. A. Kozlov
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Email: fake@neicon.ru
ORCID iD: 0000-0003-3852-3969
24 Kashirskoe Shosse, Moscow 115478 Russian Federation
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