The effect of oral cavity condition on expression of saliva biomarkers in patients with oral mucosa pathology
https://doi.org/10.17650/2222-1468-2024-14-3-83-91
Abstract
Introduction. Despite visual accessibility of the elements of tumor lesions in the oral mucosa, patients with this pathology rarely seek medical help. Regeneration of the mucosa is a long process taking varying time depending on the location of the lesions. Asymptomatic tumor process leads to its diagnosis at late stages.
Aim. To develop clinical and proteomic approach to diagnosis of malignancies of the oral mucosa at the stage of out-patient dentist appointment.
Clinical observations. Examples of extended clinical, dental and immunoenzymatic monitoring in patients with elements of tumor lesions of the oral mucosa with long-term course are presented.
Conclusion. The use of extended clinical, dental and immunoenzymatic analysis of oral fluid in patients with elements of tumor lesions of the oral mucosa allows to diagnose this pathology early.
About the Authors
E. V. Kochurova
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Bld. 2, 8 Trubetskaya St., Moscow 119048
O. I. Panferova
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Bld. 2, 8 Trubetskaya St., Moscow 119048
E. O. Kudasova
Synergy University
Russian Federation
Russian Federation
80 Leningradsky Prospekt, 125080 Moscow
E. V. Izhnina
Kuban State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
4 Mitrofana Sedina St., Krasnodar 350063
O. S. Guyter
I.P. Pavlov Ryazan State Medical University, Ministry of Health of the Russia
Russian Federation
Russian Federation
9 Vysokovoltnaya St., Ryazan 390026
D. V. Ermolin
I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia
Russian Federation
Russian Federation
Bld. 2, 8 Trubetskaya St., Moscow 119048
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Review
For citations:
Kochurova E.V., Panferova O.I., Kudasova E.O., Izhnina E.V., Guyter O.S., Ermolin D.V. The effect of oral cavity condition on expression of saliva biomarkers in patients with oral mucosa pathology. Head and Neck Tumors (HNT). 2024;14(3):83-91. (In Russ.) https://doi.org/10.17650/2222-1468-2024-14-3-83-91
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