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Post-radiation changes in thyroid function during treatment of head and neck tumors: current state of the problem

https://doi.org/10.17650/2222-1468-2025-15-2-92-98

Abstract

Post-radiation hypothyroidism is a common complication of treatment of head and neck tumors: its incidence is 6–50 %. Even subclinical hypothyroidism is associated with such cardiovascular diseases as ischemic heart disease and myocardial infarction. This pathology can significantly affect both quality of life and lifespan of patients who underwent radiation therapy.
The article presents results of studies on identification of predictors of post-radiation hypothyroidism, as well as clinical cases demonstrating results of radiation therapy in head and neck cancer treatment.

About the Authors

S. A. Zabrovskaya
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia
Russian Federation

Svetlana Anatolyevna Zabrovskaya

3 2nd Botkinsky Proezd, Moscow 125284



A. R. Gevorkov
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia
Russian Federation

3 2nd Botkinsky Proezd, Moscow 125284



N. A. Zaitseva
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia
Russian Federation

3 2nd Botkinsky Proezd, Moscow 125284



A. A. Fedoseeva
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia
Russian Federation

3 2nd Botkinsky Proezd, Moscow 125284



A. V. Boyko
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia
Russian Federation

3 2nd Botkinsky Proezd, Moscow 125284



E. V. Khmelevskiy
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia
Russian Federation

3 2nd Botkinsky Proezd, Moscow 125284



A. D. Kaprin
P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiological Centre, Ministry of Health of Russia
Russian Federation

3 2nd Botkinsky Proezd, Moscow 125284



References

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Review

For citations:


Zabrovskaya S.A., Gevorkov A.R., Zaitseva N.A., Fedoseeva A.A., Boyko A.V., Khmelevskiy E.V., Kaprin A.D. Post-radiation changes in thyroid function during treatment of head and neck tumors: current state of the problem. Head and Neck Tumors (HNT). 2025;15(2):92-98. (In Russ.) https://doi.org/10.17650/2222-1468-2025-15-2-92-98

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ISSN 2222-1468 (Print)
ISSN 2411-4634 (Online)