Особенности клинического течения меланомы слизистых оболочек головы и шеи. Обзор литературы
https://doi.org/10.17650/2222-1468-2015-5-4-48-52
Аннотация
Меланома – злокачественная опухоль, развивающаяся из меланоцитов. Меланомы слизистых оболочек головы и шеи составляют 0,2–8,0 % всех меланом, 1 % всех новообразований головы и шеи, и более 50 % всех меланом слизистых оболочек. В отечественной и зарубежной литературе в основном встречаются описания лишь отдельных клинических случаев заболевания. Несмотря на единый гистогенез, меланомы слизистых оболочек головы и шеи имеют ряд особенностей в силу специфического анатомо-топографического расположения очага и характеризуются более неблагоприятным клиническим прогнозом по сравнению с кожными формами. При этом меланомы слизистых оболочек обладают высоким метастатическим потенциалом. Пятилетняя общая вы- живаемость не превышает 30 %. Понимание особенностей клинического течения меланомы слизистых оболочек головы и шеи необходимо для определения прогноза заболевания.
В данной статье выполнен анализ публикаций, посвященных описанию клинических проявлений заболевания и характерным особенностям клинического течения в зависимости от локализации опухоли.
Ключевые слова
Об авторах
А. В. ИгнатоваРоссия
125993, Москва, ул. Баррикадная, 2 / 1
А. М. Мудунов
Россия
115478, Москва, Каширское шоссе, 23
С. О. Подвязников
Россия
125993, Москва, ул. Баррикадная, 2 / 1
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Рецензия
Для цитирования:
Игнатова А.В., Мудунов А.М., Подвязников С.О. Особенности клинического течения меланомы слизистых оболочек головы и шеи. Обзор литературы. Опухоли головы и шеи. 2015;5(4):48-52. https://doi.org/10.17650/2222-1468-2015-5-4-48-52
For citation:
Ignatova A.V., Mudunov A.M., Podvyaznikov S.O. Clinical features of the head and neck mucosal melanoma. А review. Head and Neck Tumors (HNT). 2015;5(4):48-52. (In Russ.) https://doi.org/10.17650/2222-1468-2015-5-4-48-52