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RADIATION THERAPY OF MENINGEAL HEMANGIOPERICYTOMAS (LITERATURE REVIEW AND CLINICAL OBSERVATION)

https://doi.org/10.17650/2222-1468-2017-7-3-108-114

Abstract

Meningeal hemangiopericytomas are rare tumors of the meninges developing from pericytes. The main method of their treatment is surgery aimed at total removal of the tumor. Analysis of the literature studies shows high potential of post-operative distant radiation therapy to increase duration of relapse-free survival of these patients. The recommended total radiation dose varies from 50 to 60 Gy (and in some publications, it exceeds 60 Gy). Radiation is applied as classic fractionation and hypofractionation, and different types of radiosurgery and stereotaxic radiotherapy are suitable approaches to treatment of recurrent meningeal hemangiopericytomas in patients with a history of radiation therapy.

About the Authors

A. V. Nazarenko
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
Russian Federation
23, Kashirskoe Shosse, Moscow, 115478.


T. N. Borisova
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
Russian Federation
23, Kashirskoe Shosse, Moscow, 115478.


S. V. Medvedev
Department of Radiation Therapy, P.A. Hertzen Moscow Oncology Research Institute – branch of the National Medical Research Radiology Center, Ministry of Health of Russia.
Russian Federation
3 2nd, Botkiskiy proezd, Moscow, 125284.


D. S. Romanov
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
Russian Federation
23, Kashirskoe Shosse, Moscow, 115478.


Yu. A. Gerasimov
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
Russian Federation
23, Kashirskoe Shosse, Moscow, 115478.


A. Kh. Bekyashev
Neurosurgery Department, Research Institute of Clinical Oncology, N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
Russian Federation
23, Kashirskoe Shosse, Moscow, 115478.


A. A. Mitrofanov
Neurosurgery Department, Research Institute of Clinical Oncology, N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
Russian Federation
23, Kashirskoe Shosse, Moscow, 115478.


G. E. Gorlachev
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
Russian Federation
23, Kashirskoe Shosse, Moscow, 115478.


V. A. Boldyreva
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia.
Russian Federation
23, Kashirskoe Shosse, Moscow, 115478.


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Review

For citations:


Nazarenko A.V., Borisova T.N., Medvedev S.V., Romanov D.S., Gerasimov Yu.A., Bekyashev A.Kh., Mitrofanov A.A., Gorlachev G.E., Boldyreva V.A. RADIATION THERAPY OF MENINGEAL HEMANGIOPERICYTOMAS (LITERATURE REVIEW AND CLINICAL OBSERVATION). Head and Neck Tumors (HNT). 2017;7(3):108-114. (In Russ.) https://doi.org/10.17650/2222-1468-2017-7-3-108-114

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