Pathogenesis of chronic inflammatory processes in the maxillofacial area (peri-implantitis and periodontitis) and squamous cell carcinoma: similarities and differences (review)
https://doi.org/10.17650/2222-1468-2019-9-1-79-84
Abstract
Currently, intraosseous dental implantation is one of the most widely used methods to eliminate various defects of the dentition. Despite the achievements of modern medicine, the frequency of inflammatory complications, such as peri-implantitis, in patients after dental implantation remains relatively high. Some authors suggest the presence of similarity of peri-implantitis with squamous cell carcinoma of the oral cavity at the level of pathogenesis, as well as cases of mimicry of these different nosological units are described. In this review, we study the pathogenetic mechanisms of the emergence and development of chronic inflammatory processes on the example of dental peri-implantitis, squamous cell carcinoma of the oral cavity and periodontitis, as well as the comparison of pathogenetic patterns of these processes with the study of the possible relationship. The objective of the review was to provide readers with knowledge about the common pathogenetic mechanisms of different nosological units. First of all, the data are necessary for dentists, who must remember the principle of cancer alertness, carefully carry out differential diagnosis, change the tactics of treatment of peri-implantitis with suspected tumor process.
About the Authors
A. M. Avanesov
RUDN University; Russian Scientific Center of Roentgenoradiology
Russian Federation
6 Miklukho-Maklaya St., Moscow 117198; 86 Profsoyuznaya St., Moscow 117997.
Russian Federation
6 Miklukho-Maklaya St., Moscow 117198; 86 Profsoyuznaya St., Moscow 117997.
Yu. G. Sedov
RUDN University
Russian Federation
6 Miklukho-Maklaya St., Moscow 117198.
Russian Federation
6 Miklukho-Maklaya St., Moscow 117198.
М. Е. Balashova
RUDN University
Russian Federation
6 Miklukho-Maklaya St., Moscow 117198.
Russian Federation
6 Miklukho-Maklaya St., Moscow 117198.
References
1. Bhatavadekar N.B. Squamous cell carcinoma in association with dental implants: an assessment of previously hypothesized carcinogenic mechanisms and a case report. J Oral Implantol 2012;38(6):792—8. DOI: 10.1563/AAID-JOI-D-11-00045. PMID: 21574824.
2. Gudaryan A.A., Samoylenko I.A. Significance of violations of free radical processes and imbalance of the function of the cytokine system in the development of different activity peri-implantitis. Medichni perspektivy = Medical Prospects 2010;17(1):105—10. (In Russ.).
3. Bert M., Missika P., Giovannoli J.L. Management of implant complications. Transl. from German. Moscow: Azbuka, 2007. 356 p. (In Russ.).
4. Bragger U., Heitz-Mayfield L. ITI treatment guide. Vol. 8. Biological and hardware complications in implant dentistry. Transl. from English. Moscow: Azbuka, 2016. 215 p. (In Russ.).
5. Pinchasov G., Haimov H., Druseikaite M. et al. Oral cancer around dental implants appearing in patients with\without a history of oral or systemic malignancy: a systematic review. J Oral Maxillofac Res 2017;8(3):e1. DOI: 10.5037/jomr.2017.8301. PMID: 29142653.
6. Kaplan I., Zeevi I., Tal H. et al. Clinicopathologic evaluation of malignancy adjacent to dental implants. Oral Surg Oral Med Oral Pathol Oral Radiol 2017;123(1):103—12. DOI: 10.1016/j.oooo.2016.08.023. PMID: 27720649.
7. Gulati A., Puthussery FJ., Downie I.P., Flood T.R. Squamous cell carcinoma presenting as peri-implantitis: a case report. Ann R Coll Surg Engl 2009;91(7):W8-10. DOI: 10.1308/147870809X450584. PMID: 19833011.
8. Eguia del Valle A., Martinez-Conde Llamosas R., Lopez Vicente J. et al. Primary oral squamous cell carcinoma arising around dental osseointegrated implants mimicking peri-implantitis. Med Oral Patol Oral Cir Bucal 2008;13(8):E489-91. PMID: 18667981.
9. Oh S.H., Kang J.H., Seo Y.K. et al. Un-usual malignant neoplasms occurring around dental implants: a report of 2 cases. Imaging Sci Dent 2018;48(1):59-65. DOI: 10.5624/isd.2018.48.1.59. PMID: 29581951.
10. Raiser V., Abu-El Naaj I., Shlomi B. et al. Primary oral malignancy imitating peri-implantitis. J Oral Maxillofac Surg 2016;74(7):1383—90. DOI: 10.1016/j.joms.2016.02.008. PMID: 26973225.
11. Clapp C., Wheeler J.C., Martof A.B., Levine P.A. Oral squamous cell carcinoma in association with dental osseointegrated implants. An unusual occurrence. Arch Otolaryngol Head Neck Surg 1996;122(12):1402—3. PMID: 8956760.
12. Ignatova A.V., Mudunov A.M., Narimanov M.N. Prognostic significance of biomarkers in oral squamous cell carcinoma. Review. Opukholi golovy i shei = Head and Neck Tumors 2014;(4):28—33. (In Russ.).
13. Shchnayder S.A., Prudius A.G. Clinical assessment of the condition of the mucous membrane of the oral cavity in a zone of implantation in the postoperative period of dental im-plantation at healthy persons. Vestnik stomatologii = Bulletin of Dentistry 2015;(1):73—5. (In Russ.).
14. Panakhov N.A., Makhmudo T.G. The levels of circulating cytokines in the early post-implantation period. Kazansky meditsinsky zhurnal = Kazan Medical Journal 2017;98(6): 938-43. (In Russ.).
15. Sabirova A.I. Cytokine status in patients with generalized periodontitis and metabolic syndrome. Vestnik Kyrgyzsko-Rossiyskogo slavyanskogo universiteta = Bulletin of the Kyrgyz-Russian Slavic University 2016;16(7):102-5. (In Russ.).
16. Kovalchuk L.V., Budanova E.V., Gankovskaya L.V. et al. Role of cytokines in the mechanisms of chronic inflammation in periodontal tissue. Immunologiya = Immunology 2000;(6):24—6. (In Russ.).
17. Kharaeva Z.F., Mustafaeva F.M., Mustafaev M.Sh., Vissarionov V.A. Interleukin’s status of patients with peri-implantitis. Izvestiya Kabardino-Balkarskogo nauchnogo tsentra RAN = News of Kabardino-Balkarian Scientific Center of the RAS РАН 2014;(5):254-7. (In Russ.).
18. Gudarjan A.A., Samoilenko I.A. The role of the impairments in the function of cytokine and immune systems in pathogenesis of peri-implantitis. Vestnik stomatologii = Bulletin of Dentistry 2012;(4):63—7. (In Russ.).
19. Maschenko I.S., Gudarjan A.A., Katan E.A., Samojlenko I.A. The clinico-immunological monitoring in early and remote postoperational period after intraosseous dental implantation. Vestnik stomatologii = Bulletin of Dentistry 2013;(1):55—61. (In Russ.).
20. Mashchenko I., Gudaryan A., Shirinkin S. Modern approaches to complex treatment of dental peri-implantitis. Klinicheskaya meditsina Kazakhstana = Clinical Medicine of Kazakhstan 2015;(4):50—5. (In Russ.).
21. Gudaryan A.A., Shirinkin S.V. Results of complex treatment of dental peri-implantitis. Sciences of Europe 2016;9-2:38—44. (In Russ.).
22. Renvert S., Giovannoli J.-L. Peri-implantitis. Transl. from English. Moscow: Azbuka, 2014. P. 238. (In Russ.).
23. Tlustenko E.S. Clinical and metabolic criteria of dental peri-implantitis. Abstract of dis. ... cand. med. sciences. Samara, 2004. 22 p. (In Russ.).
24. Bulkina N.V., Morgunova V.M. Modern aspects of inflammatory periodontal disease etiology and pathogenesis. Features of refractory periodontitis clinical manifestations. Fundamentalnye issledovaniya = Fundamental Research 2012;(2-2):415—20. (In Russ.).
25. Paches A.I. Head and neck tumors. Moscow: Meditsina, 2000. P. 480. (In Russ.).
26. Kadagidze Z.G., Chertkova A.I. Immunity and cancer. Prakticheskaya onkologiya = Practical Oncology 2016;17(2):62—73. (In Russ.).
27. Antonov V.G., Kozlov V.K. Pathogenesis of oncologic diseases: immune and biochemical phenomena and mechanisms. Extracellular and cellular mechanisms of general immunodepression and immune resistance. Tsitokiny i vospalenie = Cytokines and Inflammation 2004;3(1):8—19. (In Russ.).
28. Sahingur S.E., Yeudall W.A. Chemokine function in periodontal disease and oral cavity cancer. Front Immunol 2015;6:214. DOI: 10.3389/fimmu.2015.00214. PMID: 25999952.
29. Aggarwal B.B., Shishodia S., Sandur S.K. et al. Inflammation and cancer: how hot is the link? Biochemical Pharmacology 2006;72(11):1605—21. DOI: 10.1016/j.bcp.2006.06.029. PMID: 16889756.
30. Bhandari S., Rattan V., Panda N. et al. Oral cancer or peri-implantitis: a clinical dilemma. J Prosthet Dent 2016;115(6):658—61. DOI: 10.1016/j.prosdent.2015.10.022. PMID: 26803178.
31. Javed F., Al-Askar M., Qayyum F. et al. Oral squamous cell carcinoma arising around osseointegrated dental implants. Implant Dent 2012;21(4):280—6. DOI: 10.1097/ID.0b013e31824cde85. PMID: 22814551.
Review
For citations:
Avanesov A.M., Sedov Yu.G., Balashova М.Е. Pathogenesis of chronic inflammatory processes in the maxillofacial area (peri-implantitis and periodontitis) and squamous cell carcinoma: similarities and differences (review). Head and Neck Tumors (HNT). 2019;9(1):79-84. (In Russ.) https://doi.org/10.17650/2222-1468-2019-9-1-79-84
Views:
917
Email this article 