Role of hyaluronic acid in the prevention and treatment of radiation-induced oropharyngeal mucositis
https://doi.org/10.17650/2222-1468-2019-9-3-29-37
Abstract
One of the earliest and most common adverse events of radiotherapy in patients with oropharyngeal cancers is mucositis. Radiation-induced mucositis significantly impairs the quality of life, patient compliance, and sometimes even long-term treatment outcomes. Currently, there is a wide range of drugs and techniques for the prevention and treatment of this complication. Nevertheless, these methods are not always highly effective and often have their own adverse events; therefore, the search for a universal method still continues. The present review aims to analyze the efficacy of hyaluronic acid in the prevention and treatment of oropharyngeal mucositis.
Supporting agencies: The article was published with the support of RIVIERA BIOTECH.
About the Authors
Yu. V. Alymov
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478
Russian Federation
24 Kashirskoe Shosse, Moscow 115478
А. М. Mudunov
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478
Russian Federation
24 Kashirskoe Shosse, Moscow 115478
S. B. Alieva
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478
Russian Federation
24 Kashirskoe Shosse, Moscow 115478
А. V. Ignatova
Russian Medical Academy of Continuing Professional Education, Ministry of Health of Russia; RUDN University
Russian Federation
Russian Federation
Bld. 1, 2 / 1 Barrikadnaya St., Moscow 125993; 6 Miklukho-Maklaya St., Moscow 117198
R. R. Kaledin
N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia
Russian Federation
24 Kashirskoe Shosse, Moscow 115478
Russian Federation
24 Kashirskoe Shosse, Moscow 115478
А. М. Avanesov
RUDN University; Russian Scientific Center of Roentgenoradiology
Russian Federation
Russian Federation
6 Miklukho-Maklaya St., Moscow 117198; 86 Profsoyuznaya St., Moscow 117997
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For citations:
Alymov Yu.V., Mudunov А.М., Alieva S.B., Ignatova А.V., Kaledin R.R., Avanesov А.М. Role of hyaluronic acid in the prevention and treatment of radiation-induced oropharyngeal mucositis. Head and Neck Tumors (HNT). 2019;9(3):29-37. (In Russ.) https://doi.org/10.17650/2222-1468-2019-9-3-29-37
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