The role of nutritional support in treatment of head and neck tumors: clinical case
https://doi.org/10.17650/2222-1468-2022-12-3-86-94
Abstract
The article presents a clinical observation of treatment of locally advanced squamous cell oropharyngeal carcinoma. The problems of nutritional support of patients during primary chemoradiation treatment are considered. The presented clinical case shows that use of sip feeds can significantly improve nutritional condition in patients with head and neck tumors and improve tolerability and results of antitumor treatment.
About the Authors
A. M. Mudunov
Lapino Clinical Hospital
Russian Federation
Russian Federation
111 1st Uspenskoe Shosse, Lapino Village 143081, Odintsovo Dst., Moscow Region
M. B. Pak
Lapino Clinical Hospital
Russian Federation
Russian Federation
111 1st Uspenskoe Shosse, Lapino Village 143081, Odintsovo Dst., Moscow Region
L. Ya. Wolf
Nutricia LLC
Russian Federation
Russian Federation
Bld. 1 Business center “Riga Land”, 26th km, Baltic Highway, Krasnogorsky Dst., Moscow Region 143421
References
1. Parkin D.M., Whelan S.L., Ferlay J. et al. Cancer incidence in five continents. Vol. 1–8. IARC Cancer Base No. 7. Lyon, France: International Agency for Research on Cancer, 2005.
2. The state of oncological care to the population of Russia in 2019. Ed. by A.D. Kaprin, V.V. Starinsky, A.O. Shakhzadova. Moscow: P.A. Herzen Moscow State Medical Research Institute – branch of the Federal State Budgetary Institution “NMIC of Radiology” of the Ministry of Health of Russia, 2020. 239 p. (In Russ.).
3. Kang W.X., Li W., Huang S.-G. et al. Effects of nutritional intervention in head and neck cancer patients undergoing radiotherapy: a prospective randomized clinical trial. Mol Clin Oncol 2016;5(3):279–82. DOI: 10.3892/mco.2016.943
4. Muscaritoli M., Arends J., Bachmann P. et. al. ESPEN practical guideline: Clinical Nutrition in cancer. Clin Nutr 2021;40(5): 2898–913. DOI: 10.1016/j.clnu.2021.02.005.
5. Bray F., Ferlay J., Soerjomataram I. et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.CA Cancer J Clin 2018;68(6):394–424. DOI: 10.3322/caac.21492
6. Porporato P.E. Understanding cachexia as a cancer metabolism syndrome. Oncogenesis 2016:5(2):e200. DOI: 10.1038/oncsis.2016.3
7. Laviano A., Di Lazzaro L., Koverech A. Nutrition support and clinical outcome in advanced cancer patients. Proc Nutr Soc 2018;77(4):388–93. DOI: 10.1017/S0029665118000459
8. Руководство по клиническому питанию. Под ред. В.М. Луфта. СПб.: Арт-Экспресс, 2016. Guidelines for clinical nutrition. Ed. by V.M. Luft. Saint Petersburg: Art-Express, 2016. (In Russ.).
9. Obukhova O.A. Is nutritional support necessary for patients with oncological diseases? Klinicheskaya onkogematologiya = Clinical Oncohematology 2009;2(4):343–8. (In Russ.).
10. Nutritional support for oncological diseases. Pocket reference book. Moscow: ABC-press; Russian Society of Supportive care in Oncology, 2017. 94 p. (In Russ.).
11. Li T., Lv J., Zhu G. et al. Enteral nutrition to improve nutritional status, treatment tolerance, and outcomes in patients with esophageal cancer undergoing concurrent chemoradiotherapy (CCRT): Results of a prospective, randomized, controlled, multicenter trial (NCT 02399306). J Clin Oncol 2017;35(15).
12. Shachar S.S., Deal A.M., Weinberg M. et al. Skeletal muscle measures as predictors of toxicity, hospitalization, and survival in patients with metastatic breast cancer receiving taxane-based chemotherapy. Clin Cancer Res 2017;23(3):658–65. DOI: 10.1158/1078-0432.CCR-16-0940
13. Doyle S.L., Bennett A.M., Claire L., Donohoe C.L. et al. Establishing computed tomography-defined visceral fat area thresholds for use in obesity-related cancer research. Nutr Res 2013;33(3):171–9. DOI: 10.1016/j.nutres.2012.12.007
14. Langius J.A.E., Bakker S., Rietveld D.H.F. et al. Critical weight loss is a major prognostic indicator for disease-specific survival in patients with head and neck cancer receiving radiotherapy. Br J Cancer 2013;109(5):1093–9. DOI: 10.1038/bjc.2013.458
15. Maňásek V., Bezděk K., Foltys A. et al. The impact of high protein nutritional support on clinical outcomes and treatment costs of patients with colorectal cancer. Klin Onkol Fall 2016;29(5):351–7.
16. Gevorkov A.R., Boyko A.V., Volkova E.E., Shashkov S.V. Prevalence, clinical significance and possible correction of taste and smell abnormalities in patients with oncological diseases. Opuholi golovy i shei = Head and Neck Tumors 2019;9(2):53–65. (In Russ.). DOI: 10.17650/2222-1468-2019-9-2-53-65
17. Moshurov I.P., Savenok E.V., Znatkova N.A. et al. The effect of nutritional support on the chemoradiotherapy of cancer of the oropharyngeal zone, larynx and esophagus. Materials of the IX Congress of Oncologists of Russia, Ufa, June 14–16, 2017. (In Russ.). Available at: https://old.oncology-association.ru/files/Tezisi_Onc-2017_blok.pdf.
18. Wang S., Xie H., Gong Y. et al. The value of L3 skeletal muscle index in evaluating preoperative nutritional risk and long-term prognosis in colorectal cancer patients. Sci Rep 2020;10:8153. DOI: 10.1038/s41598-020-65091-0
19. Andreyev H.J., Norman A.R., Oates J., Cunningham D. Why do patients with weight loss have a worse outcome when undergoing chemotherapy for gastrointestinal malignancies? Eur J Cancer 1998;34(4):503–9. DOI: 10.1016/s0959-8049(97)10090-9 20. Van den Berg M.G., Rasmussen-Conrad E.L., Wei K.H. et al. Comparison of the effect of individual dietary counselling and of standard nutritional care on weight loss in patients with head and neck cancer undergoing radiotherapy. Br J Nutr 2010;104(6):872–7. DOI: 10.1017/S0007114510001315
20. Schindler A., Denaro N., Russi E.G. et al. Dysphagia in head and neck cancer patients treated with radiotherapy and systemic therapies: literature review and consensus. Crit Rev Oncol Hematol 2015;96(2):372e84. DOI: 10.1016/j.critrevonc.2015.06.005 22. Ravasco P., Monteiro-Grillo I., Marques Vidal P., Camilo M.E. Impact of nutrition on outcome: a prospective randomized controlled trial in patients with head and neck cancer undergoing radiotherapy. Head Neck 2005;27(8):659–68. DOI: 10.1002/hed.20221
21. Nayel H., el-Ghoneimy E., el-Haddad S. Impact of nutritional supplementation on treatment delay and morbidity in patients with head and neck tumors treated with irradiation. Nutrition 1992;8(1):13–8.
22. Paccagnella A., Morello M., Da Mosto M.C. et al. Early nutritional intervention improves treatment tolerance and outcomes in head and neck cancer patients undergoing concurrent chemoradiotherapy. Support Care Cancer 2010;18(7):837–45. DOI: 10.1007/s00520-009-0717-0
23. Nugent B., Lewis S., O’Sullivan J.M. Enteral feeding methods for nutritional management in patients with head and neck cancers being treated with radiotherapy and/or chemotherapy. Cochrane Database Syst Rev 2013;2013(1):CD007904. DOI: 10.1002/14651858.CD007904.pub3
24. Arends J., Strasser F., Gonella S. et al. Cancer cachexia in adult patients: ESMO Clinical Practice Guidelines. Practice Guidelines 2021;6(3):100092.
Review
For citations:
Mudunov A.M., Pak M.B., Wolf L.Ya. The role of nutritional support in treatment of head and neck tumors: clinical case. Head and Neck Tumors (HNT). 2022;12(3):86-94. (In Russ.) https://doi.org/10.17650/2222-1468-2022-12-3-86-94
Views:
418
Email this article 