Review of clinical cases of internal organ metastases into the skin of the head and neck
K. A. Kretova,
O. S. Nazarko,
E. V. Kopeikina,
O. G. Goncharova,
D. A. Obukhova,
D. V. Morozov,
S. V. Sergeeva,
S. V. Sidorov,
S. P. Shevchenko https://doi.org/10.17650/2222-1468-2023-13-2-75-78
Abstract
Metastases of malignant tumors of the internal organs into the skin rarely occur, on average in 1–10 % of cases. They can be the first manifestation of malignant process in the absence of signs of the main disease or show progression of confirmed cancer. The article presents clinical cases of metastases of renal cell carcinoma and adenocarcinoma into the skin of the head and neck which currently is rare. Skin metastases are variable in their clinical manifestation. In the presented cases, resection of the lesions was required as symptomatic treatment.
About the Authors
K. A. Kretova
Novosibirsk State University
Russian Federation
Russian Federation
Kamilla Armanovna Kretova
1 Pirogova St., Novosibirsk 630090
O. S. Nazarko
Novosibirsk State University
Russian Federation
Russian Federation
1 Pirogova St., Novosibirsk 630090
E. V. Kopeikina
City Clinical Hospital No. 1
Russian Federation
Russian Federation
Bld. 5, 6 Zalessky St., Novosibirsk 630047
O. G. Goncharova
City Clinical Hospital No. 1
Russian Federation
Russian Federation
Bld. 5, 6 Zalessky St., Novosibirsk 630047
D. A. Obukhova
City Clinical Hospital No. 1
Russian Federation
Russian Federation
Bld. 5, 6 Zalessky St., Novosibirsk 630047
D. V. Morozov
City Clinical Hospital No. 1
Russian Federation
Russian Federation
Bld. 5, 6 Zalessky St., Novosibirsk 630047
S. V. Sergeeva
Novosibirsk State University
Russian Federation
Russian Federation
1 Pirogova St., Novosibirsk 630090
S. V. Sidorov
Novosibirsk State University; City Clinical Hospital No. 1
Russian Federation
Russian Federation
1 Pirogova St., Novosibirsk 630090
Bld. 5, 6 Zalessky St., Novosibirsk 630047
S. P. Shevchenko
Novosibirsk State University; City Clinical Hospital No. 1
Russian Federation
Russian Federation
1 Pirogova St., Novosibirsk 630090
Bld. 5, 6 Zalessky St., Novosibirsk 630047
References
1. Hu S.C.S., Chen G.-S., Wu C.-S. et al. Rates of cutaneous metastases from different internal malignancies: experience from a Taiwanese medical center. J Am Acad Dermatol 2009;60(3): 379–87. DOI: 10.1016/j.jaad.2008.10.007
2. Golovakhina D.K., Golovakhin K.N., Zagashvili I.V. Dermatological markers of malignant tumors: skin metastases, precancrosis and paraneoplasia (clinical and diagnostic features). Voennaya medicina = Military Medicine 2015;2:95–101. (In Russ.).
3. Golousenko I.Yu. Skin metastases in malignant tumors of internal organs. Topical issues of dermatovenerology, cosmetology and reproductive health: collection of articles of the Interdisciplinary regional Scientific and Practical Conference of Dermatovenerologists and Cosmetologists (Krasnoyarsk, November 27, 2020). Krasnoyarsk, 2020. Pp. 54–60. (In Russ.).
4. Jour G., Al-Rohil R.N. Cutaneous metastases. Diagn Histopathol 2019;25(3):87–95.
5. Shah S.R., Applebaum D.S., Potenziani S. et al. Cutaneous metastasis to the scalp as the primary presentation of colorectal adenocarcinoma. Dermatol Online J 2017;23(11):13030/qt31p698nz.
6. Errami M., Margulis V., Huerta S. Renal cell carcinoma metastatic to the scalp. Rare Tumors 2016;8(4):139–41. DOI: 10.4081/rt.2016.6400
7. Hussein M.R. Skin metastasis: a pathologist’s perspective. J Cutan Pathol 2010;37(9):e1–20. DOI: 10.1111/j.1600-0560.2009.01469.x
8. Jaros J., Hunt S., Mose E. et al. Cutaneous metastases: a great imitator. Clin Dermatol 2020;38(2):216–22. DOI: 10.1016/j.clindermatol.2019.10.004
9. Strickley J.D., Jenson A.B., Jung J.Y. Cutaneous metastasis. Hematol Oncol Clin North Am 2019;33(1):173–97. DOI: 10.1016/j.hoc.2018.08.008
10. Habermehl G., Ko J. Cutaneous metastases: a review and diagnostic approach to tumors of unknown origin. Arch Pathol Lab Med 2019;143(8):943–57. DOI: 10.5858/arpa.2018-0051-RA
11. Alcaraz I., Cerroni L., Rutten A. et al. Cutaneous metastases from internal malignancies: a clinicopathologic and immunohistochemical review. Am J Dermatopathol 2012;34(4):347–93. DOI: 10.1097/DAD.0b013e31823069cf
Review
For citations:
Kretova K.A., Nazarko O.S., Kopeikina E.V., Goncharova O.G., Obukhova D.A., Morozov D.V., Sergeeva S.V., Sidorov S.V., Shevchenko S.P. Review of clinical cases of internal organ metastases into the skin of the head and neck. Head and Neck Tumors (HNT). 2023;13(2):75-78. (In Russ.) https://doi.org/10.17650/2222-1468-2023-13-2-75-78
Views:
343
Email this article 