TREATMENT OPTIONS FOR LOCOREGIONAL RECURRENCES OF ORAL AND OROPHARYNGEAL MUCOSAL SQUAMOUS CELL CARCINOMA
https://doi.org/10.17650/2222-1468-2014-0-1-24-29
Abstract
The study included 314 patients with recurrent squamous cell carcinoma of the oral cavity and oropharynx after radical treatment. Patients were divided into groups depending on the timing – patients with early recurrence (n = 162), and late recurrence (n = 152 ), and depending on the type of treatment of recurrent tumors: conservative treatment group (n = 56 ), surgical (n = 235) and combined treatment (n = 23) group. A comparative evaluation of the effectiveness of the treatment of these patients based on the results of treatment, survival rates, the frequency and severity of complications. The conservative therapy of recurrent tumors of the oral cavity if surgical treatment is impossible is effective, especially in cases of late recurrent tumors but only surgical or combined treatment may reach the five-year survival rate in patients with recurrent tumor, cancer of the oral cavity and oropharynx.
About the Authors
I. A. Zaderenko
A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia; , Moscow
Russian Federation
Department of Maxillofacial Surgery
Russian Federation
Department of Maxillofacial Surgery
A. Yu. Drobyshev
A.I. Evdokimov Moscow State University of Medicine and Dentistry, Ministry of Health of Russia; , Moscow
Russian Federation
Department of Maxillofacial Surgery
Russian Federation
Department of Maxillofacial Surgery
R. I. Azizyan
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Department of Surgery for Upper Respiratory and Digestive Tract Tumors
Russian Federation
Department of Surgery for Upper Respiratory and Digestive Tract Tumors
S. V. Aliyeva
N.N. Blokhin Russian Cancer Research Center, Russian Academy of Medical Sciences, Moscow
Russian Federation
Department of Surgery for Upper Respiratory and Digestive Tract Tumors, Department of Radiation Oncology
Russian Federation
Department of Surgery for Upper Respiratory and Digestive Tract Tumors, Department of Radiation Oncology
References
1. Матякин Е.Г., Уваров А.А., Матякин Г.Г., Парамонов В.А. Особенно- сти хирургических вмешательств у боль- ных раком полости рта и ротоглотки по- сле радикального курса лучевой терапии. Медицинская радиология 1991;36(4) 33–6.
2. Пачес А.И. Опухоли головы и шеи. М.: Медицина, 2000. 490 с.
3. Liao C.T., Chang J.T., Wang H.M. et al. Salvage therapy in relapsed squamous cell carcinoma of the oral cavity: how and when? Cancer 2008 Jan 1;112(1):94–103.
4. Liu S.A., Wong Y.K., Lin J.C. et al. Impact of recurrence interval on survival of oral cavity squamous cell carcinoma patients after local relapse. Otolaryngol Head Neck Surg 2007;136(1):112–8.
5. Agra I.M., Carvalho A.L., Ulbrich F.S. et al. Prognostic factors in salvage surgery for recurrent oral and oropharyngeal cancer. Head Neck 2006;28(2):107–13.
6. Liao C.T., Chang J.T., Wang H.M. et al. Survival in squamous cell carcinoma of the oral cavity: differences between pT4 N0 and other stage IVA categories. Cancer 2007;110(3):564–71.
Review
For citations:
Zaderenko I.A., Drobyshev A.Yu., Azizyan R.I., Aliyeva S.V. TREATMENT OPTIONS FOR LOCOREGIONAL RECURRENCES OF ORAL AND OROPHARYNGEAL MUCOSAL SQUAMOUS CELL CARCINOMA. Head and Neck Tumors (HNT). 2014;(1):24-29. (In Russ.) https://doi.org/10.17650/2222-1468-2014-0-1-24-29
Views:
800
Email this article 