ANALYSIS OF RELAPSE RATE AND METASTASES OF HIGH DIFFERENTIATED THYROID CANCER

 Analysis of rate of relapses and metastases with well-differentiated thyroid cancer was performed for patients in 2009 to 2013. The study involved 189 patients with thyroid cancer including 98 (51.9 %) patients suffering from papillary thyroid cancer, 77 (40.7 %) patients suffering from follicular thyroid cancer, and 14 (7.4 %) patients suffering from medullary thyroid cancer. 2.04 % of the 98 patients suffering from papillary thyroid cancer manifested a relapse, and lymphogenic metastases of cancer were revealed with 1.0 % of patients. With follicular thyroid cancer (n = 77), lymphogenic metastases were registered in 7.8 % of cases, relapses were revealed in 1.3 % of cases. This analysis demonstrated that observation of patients for 5 years revealed a higher percentage of metastases with patients that suffered from follicular thyroid cancer.

1. Барчук А.С. Рецидивы дифференцированного рака щитовидной железы. Практическая онкология 2007;8(1):35–41. [Barchuk A.S. Relapses of differentiated thyroid cancer. Prakticheskaya onkologiya = Practical Oncology 2007;8(1):35–41 (In Russ.)].

2. Пинский С.Б., Дворниченко В.В., Белобородов В.А. Опухоли щитовидной железы. Иркутск, 1999. [Pinskiy S.B., Dvornichenko V.V., Beloborodov V.A. Thyroid gland tumors. Irkutsk, 1999 (In Russ.)].

3. Hegedus L., Bonnema S.J., Bennedbaek F.N. Management of simple nodular goiter: current status and future perspectives. Endocr Rev 2003;24(1):102–32.

4. Новожилова Е.Н. Показания к повторным операциям при раке щитовидной железы. Онкология на рубеже веков. М., 1999. С. 270–271. [Novozhilova E.N. Indications for repeated surgical operations with thyroid cancer. Oncology at the turn of the century. Moscow, 1999. Pp. 270–271 (In Russ.)].

5. Чиссов В.И., Ольшанский В.О., Трофимова Е.Ю., Новожилова Е.Н. Показания к повторным операциям при раке щитовидной железы. Российский онкологический журнал 1998;1:27–9. [Chissov V.I., Olshanskiy V.O., Trofimova E.Yu., Novozhilova E.N. Indications for repeated surgical operations with thyroid cancer. Rossiyskiy Onkologicheskiy Zhurnal = Russian Journal of Oncology 1998;1:27–9 (In Russ.)].

6. Яйцев С.В. Клинико-эпидемиологическая характеристика, пути профилактики и прогнозирования рака щитовидной железы. Автореф. дис. … д-ра мед. наук. Челябинск, 2000. С. 43. [Yaitsev S.V. Clinical and epidemiological characteristics, methods of prevention and prognosis of thyroid cancer. Author's abstract ... of MD thesis. Chelyabinsk, 2000. P. 43 (In Russ.)].

7. Duren M., Siperstein A.E., Shen W. et al. Value of stimulated serum thyroglobulin levels for detecting persistent or recurrent differentiated thyroid cancer in highand low-risk patients. Surgery 1999;126(1): 13–9.