Neoadjuvant target therapy of differentiated thyroid cancer (clinical observation)
https://doi.org/10.17650/2222-1468-2017-7-1-86-90
Abstract
In the article a case of non-resectable differentiated thyroid cancer (DTC) is described. A recurrent thyroid tumor deforms the oropharyngeal lumen and laryngeal vestibule and bears down on the left esophageal wall and trachea. The authors present literature data on Nexavar target therapy and focus on the fact that no cases of combination treatment with target therapy and surgery of non-resectable progressive DTC were described until now. In view of this, this clinical report is unique and dictates a need to determine new Nexavar (Sorafenib) indications for use in a neoadjuvant regimen.
About the Authors
P. A. Isaev
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
S. V. Vasilkov
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
I. S. Pimonova
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
F. E. Sevrukov
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
V. V. Polkin
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
D. Yu. Syomin
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
A. A. Ilyin
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
V. S. Medvedev
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
N. K. Silantyeva
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
T. A. Agababyan
A.F. Tsyb Medical Radiological Research Center – branch of the National Medical Research Radiological Center at the Ministry of Health of Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
Russian Federation
4 Korolyov St., Obninsk 249036, Kaluga Region, Russia
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Review
For citations:
Isaev P.A., Vasilkov S.V., Pimonova I.S., Sevrukov F.E., Polkin V.V., Syomin D.Yu., Ilyin A.A., Medvedev V.S., Silantyeva N.K., Agababyan T.A. Neoadjuvant target therapy of differentiated thyroid cancer (clinical observation). Head and Neck Tumors (HNT). 2017;7(1):86-90. (In Russ.) https://doi.org/10.17650/2222-1468-2017-7-1-86-90
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